A Visual Guide to Genome Editors
Codon
JUNE 5, 2025
If the same virus invades the cell a second time, the gRNA’s spacer sequence will bind to the matching viral DNA sequence, then be cut by the Cas protein. It was first characterized in 2016 by Feng Zhang’s lab. The core of the CRISPR immune response is a guide RNA (gRNA) that binds to a CRISPR-associated (Cas) protein.
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