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Levers for Biological Progress

Codon

Scientists are already building a model that can, for example, look at which RNA molecules are expressed in a cell at t=0 and predict how those molecules will change at t=1. Even more fundamentally, a virtual cell is a way to encapsulate the current extent of our biological knowledge. Even the humble E.

DNA 133
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New machine learning-based single-cell search engine makes cell annotation faster, more efficient

Broad Institute

Scientists then annotate the cells with this information, a process that can take days or even weeks, depending on the number of cells being labeled, and requires labor-intensive literature and database searches. We wanted to build a tool like that for cell biology. Overall, how can AI help advance cell biology?

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Women in STEM with Juliet Williams

Drug Target Review

I sharpened my focus in my early teen age years when I decided I wanted to harness my interest in human biology to make medicines for people. I studied Natural Sciences at the University of Cambridge, where I was exposed to a range of disciplines from chemistry to physiology, specialising in my last year in biochemistry.

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Cancer metastasis: breakthrough in therapeutic strategies

Drug Target Review

This discovery sheds new light on the intricate mechanisms at play within cancer cells when faced with adverse conditions. When bound to GRP78, ID2 loses its inhibitory function, leading to increased invasiveness of cancer cells.

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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

She has played a key role inbuilding the target identification platform and a proprietary database of transcriptome-wide, functional RNA structures. Rising from Research Scientist to Senior Scientist, I supported early-stage DD efforts within their Protein Science group, based in Cambridge, UK.

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Fast Biology

Codon

At any given moment, thousands of messenger RNAs are being translated into proteins by ribosomes, which are protein-making machines that are, themselves, made from a mixture of proteins and RNA. 3 Part of the beauty of science is that it builds upon itself, one experiment at a time. Hundreds of proteins do this at the same time.

RNA 98
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A research team searches for every gene that helps tumors evade immunotherapy

Broad Institute

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. Along the way, TIDE is showing how careful, systematic science at scale can quickly home in on promising drug targets.

Research 137