Broad Institute

JUNE 18, 2024

Simple test for flu could improve diagnosis and surveillance By Allessandra DiCorato June 18, 2024 Breadcrumb Home Simple test for flu could improve diagnosis and surveillance A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus.

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The Pharma Data

DECEMBER 3, 2020

New Tau Protein is Abnormal in Very Early Alzheimer’s Disease. Investigators with the University of Gothenburg identified new forms of tau protein that become abnormal in the very early stages of Alzheimer’s disease, even before the development of cognitive problems. Kidney Disease Leading Risk Factor for COVID-related Hospitalization.

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Broad Institute

DECEMBER 13, 2023

Related news Researchers map brain cell changes in Alzheimer’s disease Courtesy of the Chen and Macosko labs. The researchers also discovered clues about cellular function and the potential roles of brain structures in disease. Courtesy of the Chen and Macosko labs. Our results underscore the need to study them more deeply.”

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The Pharma Data

DECEMBER 17, 2020

(NASDAQ: REGN ) today announced that the New England Journal of Medicine (NEJM) has published initial clinical data from an ongoing seamless Phase 1/2/3 trial of the antibody cocktail casirivimab and imdevimab in non-hospitalized patients with COVID-19. “The investigational cocktail is now available to indicated high-risk U.S.

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The Pharma Data

MARCH 8, 2021

The companies today reported findings on one secondary objective from the Phase 2a study, showing a reduction in time (days) to negativity of infectious virus isolation in nasopharyngeal swabs from participants with symptomatic SARS-CoV-2 infection, as determined by isolation in Vero cell line culture. This press release features multimedia.

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The Pharma Data

OCTOBER 30, 2020

(NASDAQ: REGN) received today a recommendation from the independent data monitoring committee (IDMC) for the REGN-COV2 antibody cocktail treatment trials for COVID-19 that the current hospitalized patient trial be modified. About the REGN-COV2 Trial in Hospitalized Patients. Cohort 1A: patients not requiring oxygen.

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Broad Institute

MAY 30, 2023

By Andrea Tamayo May 30, 2023 Credit: Allison Dougherty, Broad Communications Isabella Teixeira-Soldano studies single cells to better understand disease progression. Then, I started working in shipping and handling, where I was responsible for shipping testing kits to schools, hospitals, and other places.

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The Pharma Data

JANUARY 13, 2021

Siew Ng, a professor from the Institute of Digestive Disease at the Chinese University of Hong Kong. “Restoration of the missing beneficial bacteria might boost our immunity against SARS-CoV2 virus and hasten recovery from the disease,” she said.

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The Pharma Data

AUGUST 28, 2020

Earlier studies have found the vast majority of children with the virus have mild or no symptoms. But these findings shed light on the unresolved question of how likely children are to spread the virus to others. How severely do they get the virus? Do they pass it on to others? What does the South Korean study say?

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Broad Institute

SEPTEMBER 30, 2024

Today, about a third of Broad’s Terra users are from the public health workforce; in the US, 76 state and local public health labs use the platform for preventing and monitoring infectious disease spread in their communities. This was true in the US and all the more in the Global South, where the burden of infectious disease is the highest.

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The Pharma Data

NOVEMBER 19, 2020

Emily Adhikari, medical director of perinatal infectious diseases at Parkland Hospital in Dallas. “Most women with asymptomatic or mild infection will be relieved to know that their babies are unlikely to be affected by the virus,” Adhikari said. At the start of the pandemic, the U.S. © 2020 HealthDay.

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The Pharma Data

DECEMBER 17, 2020

Among those under 18, the virus is easily spread by close contact with family members who have COVID-19 and at gatherings where people don’t wear masks, but going to school wasn’t linked to positive COVID-19 tests, according to the researchers. “We’ve got to play by the rules. The report was published Dec.

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The Pharma Data

OCTOBER 28, 2020

REGN-COV2 significantly reduced viral load and patient medical visits (hospitalizations, emergency room, urgent care visits and/or physician office/telemedicine visits). In the overall patient group with detectable virus at baseline, the average daily reduction in viral load through day 7 was a 0.36 There was a 1.08

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The Pharma Data

AUGUST 20, 2020

Medical detection dogs Bramble (left) and Lexi during a visit to Kettering General Hospital. Eleven hospitals across the UK are taking part in the study, with scientists hoping at least 3,500 staff will provide “odour samples” Testing has begun to see if medical detection dogs can be trained to smell the disease.

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Nvidia Developer: Drug Discovery

OCTOBER 5, 2021

Recently published in the Proceedings of the National Academy of Sciences , the research develops a deep learning model that determines the best drug combinations for fighting the virus, despite having relatively limited data. These targets play a major role in drug therapy by creating a place for a drug to bind and inhibit disease growth.

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The Pharma Data

AUGUST 11, 2020

It has not received general approval to treat the virus in the US, but has in several European countries and Japan. The request for approval comes nearly two months after a study from the National Institute of Allergy and Infectious Diseases which showed positive results, with the drug effectively blocking the virus from replicating.

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The Pharma Data

JULY 8, 2021

People who receive mRNA COVID-19 vaccines are up to 91 percent less likely to develop the disease than those who are unvaccinated, according to a new nationwide study of eight sites, including Salt Lake City. Only 204 (5%) of the participants eventually tested positive for SARS-CoV-2, the virus that causes COVID-19.

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DrugBank

JUNE 13, 2024

Similarly, for cardiovascular diseases, implantable drug-eluting stents can deliver controlled doses of anti-proliferative drugs directly to the site of arterial blockage, preventing restenosis (re-narrowing) and improving long-term integrity of the vessel.  

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The Pharma Data

AUGUST 3, 2020

Although there is still much that doctors don’t know about how pregnancy can be affected by the virus, pregnant women do not appear to become more unwell than other healthy adults who contract it. Can I pass the virus to my baby during pregnancy? But what do we know about its impact on pregnancy? What did recent UK research find?

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The Pharma Data

JANUARY 11, 2021

The COVID-19 vaccines work by teaching the immune system to protect against the virus, experts said. Neither of the two vaccines approved in the United States — made by Pfizer-BioNTech and Moderna — contains the live virus. Fahad Khalid, chief of hospital medicine at Penn State Health Hershey Medical Center in Hershey, Pa.,

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The Pharma Data

DECEMBER 29, 2020

“It was like she was experiencing a movie, like ‘Kill Bill,'” Dr. Hisam Goueli, a psychiatrist at South Oaks Hospital in N.Y., A British study of mental complications in 153 patients hospitalized with COVID-19 found that 10 people had “new-onset psychosis.” told the Times.

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The Pharma Data

SEPTEMBER 3, 2020

Anyone with any of these should isolate and get tested for the virus. The US Centres for Disease Control already lists nausea or vomiting and diarrhoea among possible Covid-19 symptoms. None of the children in the study was seriously ill or needed to be admitted to hospital. ” Source link.

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The Pharma Data

AUGUST 16, 2021

Vaccination is our most effective means of preventing COVID-19 infection – especially severe disease and hospitalization – and its profound impact on protecting lives is indisputable. We continuously strive to stay at least one step ahead of the virus. today announced that they have submitted Phase 1 data to the U.S.

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The Pharma Data

JULY 12, 2021

The data were presented during the late-breaking clinical trials session at the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID). Headquartered in Miami, Florida, Ridgeback Biotherapeutics LP is a biotechnology company focused on emerging infectious diseases. About Molnupiravir. Source link: [link].

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The Pharma Data

FEBRUARY 23, 2022

. * In the VAT08 Phase 3 primary series trial, two doses of the Sanofi-GSK vaccine in seronegative populations demonstrated: * 100% efficacy against severe COVID-19 disease and hospitalizations * 75% efficacy against moderate or severe COVID-19 disease * 57.9% for efficacy, immunogenicity and safety compared to a placebo.

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NIH Director's Blog: Drug Development

APRIL 2, 2020

With so much information swirling around these days about the coronavirus disease 2019 (COVID-19) pandemic, it would be easy to miss one of the most interesting and significant basic science reports of the past few weeks. ACE2 is the receptor that the virus uses to gain entry. Credit: Adapted from Yan R., Science, 2020.

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The Pharma Data

DECEMBER 21, 2020

(Nasdaq:BCRX) today announced that data from part 1 of a clinical trial of its broad-spectrum antiviral, galidesivir, showed that galidesivir was safe and generally well tolerated in patients infected with SARS-CoV-2, the virus that causes COVID-19. It is in advanced development for the treatment of Marburg virus disease.

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NIH Director's Blog: Drug Development

OCTOBER 27, 2020

Science, 2020 One way to fight COVID-19 is with drugs that directly target SARS-CoV-2, the novel coronavirus that causes the disease. Another promising strategy is drugs that target the proteins within human cells that the virus needs to infect, multiply, and spread. Credit: DE Gordon et al., And the results were quite striking.

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The Pharma Data

DECEMBER 20, 2020

20 , 2020 /PRNewswire/ — The broad spectrum antiviral therapeutic, ‘hzVSF-v13(humanized Virus Suppressing Factor)’ being developed by ImmuneMed , is on track to progress as a treatment for the COVID-19 pneumonia patients. CHUNCHEON, South Korea , Dec. Media Contact.

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The Pharma Data

JUNE 26, 2021

The trial will evaluate the safety and immunogenicity of a monovalent flu vaccine candidate coding for the hemagglutinin protein of the A/H3N2 strain of the influenza virus. In June 2020, the two companies built upon the existing agreement to pursue novel mRNA vaccines to broadly address current and future infectious diseases.

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The Pharma Data

SEPTEMBER 25, 2020

Early tests showed the jab, developed by US biotechnology company Novavax, leads to high levels of virus-fighting antibodies being produced. “It’s a technology that we are more familiar with,” Prof Paul Heath, who is leading the trial at St George’s University Hospitals NHS Foundation Trust, told the BBC.

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The Pharma Data

JANUARY 15, 2021

“People with all kinds of cardiovascular risk factors and disease should definitely get vaccinated to protect themselves and their families from COVID-19,” said Dr. Mitchell Elkind, a professor of neurology and epidemiology at NewYork-Presbyterian Hospital/Columbia University Irving Medical Center in New York City.

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The Pharma Data

AUGUST 9, 2021

With this goal in mind, the team led by ISGlobal researcher Carlota Dobaño followed a cohort of healthcare workers at the Hospital Clinic (SEROCOV study) from the beginning of the pandemic, in order to evaluate the levels of antibodies against different SARS-CoV-2 antigens over time. No reinfections were observed in the cohort.

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The Pharma Data

OCTOBER 22, 2020

Food and Drug Administration (FDA) has approved the antiviral drug Veklury (remdesivir) for the treatment of patients with COVID-19 requiring hospitalization. As an antiviral drug, Veklury works to stop replication of SARS-CoV-2, the virus that causes COVID-19.

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The Pharma Data

JUNE 1, 2022

Scientists who have long studied this molecule’s functions in bacterial infections traced development of extensive lung damage in infected mice to heightened levels of the enzyme triggered by the invading SARS-CoV-2 virus. They used a version of the SARS-CoV-2 virus that other scientists have engineered specifically to cause disease in mice.

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The Pharma Data

OCTOBER 14, 2020

The coronavirus disease 2019 (COVID-19) pandemic has placed the world in a tailspin, which the healthcare industry has responded to in kind with the development and rapid deployment of tests designed to detect infection. Below is an overview of these different tests, including what they can do to identify the disease and their limitations.

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The Pharma Data

OCTOBER 27, 2021

. “The main finding in our study is that the equine hyperimmune globulins antibodies developed against the spike protein of the ancestral SARS-CoV-2 had high neutralizing action against the new variants of the virus, such as the gamma strain. Silva, from the Federal University of Rio de Janeiro, and coordinator of the study.

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