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New tRNA tech aims to rewrite rare disease treatment

Drug Target Review

One company leading the charge in this revolution is Alltrna , whose pioneering work in engineered transfer RNA (tRNA) therapeutics is offering new hope for patients with rare genetic diseases. we are first focused on engineering tRNAs to restore protein production in diseases caused by premature termination codons.

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What single cells are revealing about brain disorders

Drug Target Review

Xenium takes this further with in situ analysis at subcellular resolution, detecting RNA and protein molecules directly within tissues using high-resolution imaging. How AI fits in Artificial intelligence (AI) is also beginning to play a larger role across 10x’s product portfolio.

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Building Korro Bio: A CEO’s Perspective on Innovation and Risk Management

LifeSciVC

Founding Vision: Harnessing RNA Editing for Transformative Medicine Korro Bio’s story began in 2018, co-founded by a remarkable group: Jean-François Formela, M.D. Academic specializing in RNA editing). The ability of modifying RNA enabled us to sidestep many of the potential risks associated with permanent DNA editing.

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The Magic of Fast Feedback Loops

Codon

DNA sequencing and synthesis costs have dropped precipitously, in part, because maintaining Carlson curves became a rallying point for the field. Leveraging transparency to drive competition has worked well in other fields, such as consumer products , economic policy , and cloud services.

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Levers for Biological Progress

Codon

Scientists are already building a model that can, for example, look at which RNA molecules are expressed in a cell at t=0 and predict how those molecules will change at t=1. Synthesizing a single human protein-coding gene costs several hundred dollars and even a simple PCR machine (used for amplifying DNA) costs between $1,500 and $50,000.

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Optical density and absorbance measurements | BMG LABTECH

BMG Labtech

Whether it is determining concentrations of molecules like proteins or DNA, looking at enzyme kinetics for crucial reactions, or measuring something as fundamental as cell growth, you will find references to absorbance or optical density measurements. Optical density is also widely used for many scientific applications.

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Twist Bioscience

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