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Case Study: Two Examples of Successful Automation Integration at Altasciences for Pharmacokinetic Studies

Alta Sciences

Motivated by our success, we are actively working to enhance the automation and optimization of sample dilution and reagent addition for ELISA and ECLIA assays to support large pharmacokinetic clinical trials. Automated workflows ensure higher quality, better efficiency, and consistency across projects of all sizes.

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David Liu receives Breakthrough Prize in Life Sciences

Broad Institute

The organization has honored Liu for the development of the gene editing platforms base editing and prime editing, which can correct the vast majority of known disease-causing genetic variations and have already been used in at least 15 clinical trials, with life-saving results.

Science 144
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Forging a Path Forward for Substance Abuse Potential Studies With the Cross-Company Abuse Liability Council By Beatrice Setnik, PhD

Alta Sciences

We are the leading organization in conducting substance abuse clinical trials, with principal investigators who collectively bring over 50 years of experience in the field of substance abuse, and with a team of physicians who have extensive expertise in identifying participants for substance abuse studies. Tags Clinical Trials Weight 16

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Q&A: One scientist’s bold vision to make on-demand treatments routine for life-threatening rare genetic diseases

Broad Institute

Together, these technologies have entered at least 19 clinical trials, with clinical results from seven of those trials reported so far — all showing that the base edit or prime edit resulted in patient benefit. While doctors are cautious about using the word "cure" so early, it is a triumph for K.J.'s Today, K.J.

Treatment 133
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AC102 Eliminates Tinnitus in Preclinical Study

The Pharma Data

This would be a great relief for patients and doctors who currently have no approved drug treatment available.” Building on those results, AudioCure has now launched a Europe-wide Phase 2 clinical trial aimed at evaluating the drug’s effectiveness in treating both sudden hearing loss and tinnitus in human patients.

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Novartis Fabhalta Boosts Hemoglobin in PNH Patients

The Pharma Data

This marks a significant step forward for both patients and their doctors in choosing a convenient, effective, well-tolerated treatment that can enable them to manage their condition while retaining greater control over their daily routines.”

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The Long Road to End Tuberculosis

Codon

Still, while these developments provide cause for hope, each drug or vaccine faces a variety of challenges, ranging from financial incentives for clinical trials to the difficulty of discovering new antimicrobials that pass safety and efficacy tests. A phase 3 clinical trial for M72/AS01E, funded by the Gates Foundation, began this year.

Vaccine 115