BioPharma Drive: Drug Pricing
JANUARY 30, 2025
Despite high demand for an option like Journavx, doctors fear the drug’s price could be a major hangup for insurers, potentially limiting patients’ ability to access it.
Science Daily: Pharmacology News
JANUARY 30, 2025
U of T Scarborough researchers have directly linked population decline in polar bears living in Western Hudson Bay to shrinking sea ice caused by climate change.
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FDA Law Blog: Drug Discovery
JANUARY 30, 2025
By Mark A. Tobolowsky & Charles G. Raver & James E. Valentine We recently blogged about a new December 2024 draft guidance about accelerated approval (the December 2024 draft guidance). That post largely focused on endpoints as well as the broader context for when accelerated approval is appropriate. However, as we note in that post, the design, timing of initiation, and timely conduct of confirmatory trials are also important considerations in FDAs determination of whether accelerated
Science Daily: Pharmacology News
JANUARY 30, 2025
The antibody targets a stable part of the bird flu virus, ensuring that the immune protection can resist new variants and offer long-term protection against the globally spreading airborne infection.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Chemical Biology and Drug Design
JANUARY 30, 2025
The remarkable therapeutic potential of luteolin against cervical cancer can be ascribed to its profound influence on amino acid and nucleotide metabolism, substantiated by the seamless integration of metabolomics, bioinformatics, and molecular docking techniques in this comprehensive investigation. ABSTRACT The incidence of cervical cancer is high among women globally.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
JANUARY 30, 2025
THURSDAY, Jan. 30, 2025 -- People of color now have less access to prescription opioid painkillers than white patients, an unintended consequence of efforts to stem Americas opioid epidemic.Communities of color have a 40% to 45% lower distribution.
Science Daily: Pharmacology News
JANUARY 30, 2025
A green alga that grows in lakes and rivers could be the next 'superfood' -- helping scientists to tackle global food security challenges while promoting environmental sustainability.
Drugs.com
JANUARY 30, 2025
THURSDAY, Jan. 30, 2025 -- If you have a bag of Wegmans breaded chicken breast nuggets in your freezer, you may want to check the label before your next meal.The U.S. Department of Agricultures Food Safety and Inspection Service (FSIS) has issued a.
Science Daily: Pharmacology News
JANUARY 30, 2025
A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors to new methods for studying complex processes in cells and could pave the way for significant advances in medicine and synthetic biology.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
JANUARY 30, 2025
THURSDAY, Jan. 30, 2025 -- Weight-loss surgery can protect the liver health of patients with obesity and fatty liver disease, a new study reports.Patients had a 72% lower risk of developing serious complications of liver disease after undergoing.
Science Daily: Pharmacology News
JANUARY 30, 2025
Zaps of static electricity might be a wintertime annoyance, but to certain scientists, they represent an untapped source of energy. Using a device called a triboelectric nanogenerator (TENG), mechanical energy can be converted into electrical energy using triboelectric effect static. Many TENGs contain expensive, specially fabricated materials, but one team has instead used inexpensive store-bought tape, plastic and aluminum metal.
Chemical Biology and Drug Design
JANUARY 30, 2025
New 9H purine derivatives were designed and synthesized, and CDK9 inhibitory activity were evaluated. Compound B5 behaved as a highly selective inhibitors of CDK9. ABSTRACT Cyclin-dependent kinase 9 (CDK9) is considered as an important target in the research of antitumor drugs. Taking the CDK2/9 inhibitor CYC065 as the positive control and an in-house library compound ( 64 ) as the lead compound, four classes of 22 target compounds with 9H purine as the core structure were designed to establish
Science Daily: Pharmacology News
JANUARY 30, 2025
Experts from the global Earth science community have pieced together what happened during the massive Sikkim flood to try to help others prepare for similar disasters.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
JANUARY 30, 2025
THURSDAY, Jan. 30, 2025 -- Heavy weed use appears to dull the brains of young adults, particularly affecting their short-term working memory, a new study suggests.MRI scans showed less brain activation in heavy tokers performing tasks that tested.
Science Daily: Pharmacology News
JANUARY 30, 2025
Your parents were right: Scratching an itchy rash really does make it worse. Now we know why, thanks to new research that uncovers how scratching aggravates inflammation and swelling in a mouse model of a type of eczema called allergic contact dermatitis.
Chemical Biology and Drug Design
JANUARY 30, 2025
A pyrazolopyrimidine, 2-((4-methoxyphenyl)amino)-7-(pyridin-2-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile exhibits TLR7 agonistic activity and stimulates an innate immune response in RAW264.7 macrophages. ABSTRACT Compounds containing pyrazolopyrimidine scaffolds were designed and synthesized as toll-like receptor 7 (TLR7) agonists. Thirty-three compounds, including 22 novel compounds, were prepared, and their structures were identified using nuclear magnetic resonance spectroscopy and mass spec
Science Daily: Pharmacology News
JANUARY 30, 2025
Researchers have designed flexible, bat-like wings that boost lift and improve flight performance. This innovation could lead to more efficient drones or energy-harvesting technologies.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
JANUARY 30, 2025
The testing company ended last year with $79 million and told investors it will need to raise money to fund its operations and financial commitments.
Science Daily: Pharmacology News
JANUARY 30, 2025
Studies of sediment cores from the sea floor and the coastal regions surrounding the Aegean Sea show that humans contaminated the environment with lead early on in antiquity. Geoscientists conducted the analyses, which revealed that human activity in the region resulted in lead contamination of the environment approximately 5,200 years ago -- much earlier than previously known.
Drugs.com
JANUARY 30, 2025
THURSDAY, Jan. 30, 2025 -- Seniors whose cholesterol levels spike and plummet year-to-year could be at increased risk of dementia and failing brain health, a new study suggests.Those whose cholesterol fluctuated the most had a 60% increased risk of.
Science Daily: Pharmacology News
JANUARY 30, 2025
Researchers have shown that plumes of wildfire smoke can carry contaminants hundreds of kilometers, leaving a toxic and lingering footprint which has the potential to be re-released into the environment.
BioPharma Drive: Drug Pricing
JANUARY 30, 2025
Robert F. Kennedy Jr., nominated to be health secretary, seemed unfamiliar with the particulars of the massive insurance program he'd oversee in exchanges with senators Thursday.
Science Daily: Pharmacology News
JANUARY 30, 2025
Scientists have discovered a feedback loop in the brain's odor center that seems to put smells and sounds into context. The feedback loop may help animals adjust their behaviors in response to new sensations.
BioPharma Drive: Drug Pricing
JANUARY 30, 2025
The offerings reflect an increase in IPO activity that could continue, as four other biotechs recently outlined plans to go public.
Drugs.com
JANUARY 30, 2025
THURSDAY, Jan. 30, 2025 -- Most community crisis services did not expand following the launch of the 988 Suicide & Crisis Lifeline, potentially blunting the effectiveness of the hotline, a new study says.Walk-in psychiatric services, mobile.
Science Daily: Pharmacology News
JANUARY 30, 2025
Zika virus hijacks the skin of its human host to send out chemical signals that lure more mosquitoes to infect and spread the disease further, new research shows.
BioPharma Drive: Drug Pricing
JANUARY 30, 2025
Julie Kim, currently Takeda’s U.S. head, will replace Weber in June 2026 and become one of the few female CEOs of a top drugmaker.
The Open Targets Blog
JANUARY 30, 2025
This blog post is part of a series that will explore applications and expansions of the Open Targets informatics ecosystem, particularly the Open Targets Platform and Open Targets Genetics through conversations with our users. Sam Wagenaar is a high school senior, who, during his internship last year with the Pachter Lab at the California Institute of Technology (Caltech), developed the gget opentargets module under the mentorship of Laura Luebbert and Joe Rich.
Science Daily: Pharmacology News
JANUARY 30, 2025
Being optimistic about the future may help people save more money, and the effect appears strongest among those with lower incomes, according to new research.
BioPharma Drive: Drug Pricing
JANUARY 30, 2025
Safety concerns and disappointing efficacy results have led Cargo to stop testing the treatment, cut 50% of its workforce and evaluate strategic alternatives.
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