Sun.Mar 16, 2025

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Comprehensive Characterization of Bruton’s Tyrosine KinaseInhibitor Specificity, Potency, and Biological Effects: Insights into Covalent and Noncovalent Mechanistic Signatures

Covalent Modifiers

Antonia C. Darragh, Andrew M. Hanna, Justin H. Lipner, Alastair J. King, Nicole B. Servant, and Mirza Jahic ACS Pharmacol. Transl. Sci. 2025 [link] Uncovering a drugs mechanism of action and possible adverse effects are critical components in drug discovery and development. Moreover, it provides evidence for why some drugs prove more effective than others and how to design better drugs altogether.

FDA 100
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The impact of biosimilars on biologic drug life cycle management

Drug Patent Watch

The Biosimilar Revolution: How It's Changing the Game for Biologic Drug Manufacturers As the pharmaceutical industry continues to evolve, one trend is gaining significant attention: the rise of biosimilars. For those who may be new to this concept, biosimilars are biologic drugs that are highly similar to existing biologic medicines, but at a lower cost.

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Early Detection of Colon Cancer Is Critical for Women

Drugs.com

SUNDAY, March 16, 2025 -- Colon cancer is one of the most dangerous cancers affecting women today. Despite its impact, many women miss early warning signs, mistaking them for everyday digestive issues or menopause. Understanding the risks.

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Healing My Family’s Future

Codon

By Jennifer Lai Remmel We paused outside the unit, hand in hand. “We could go home, you know,” I said, glancing at my husband, Chris. We might have been buying a car or questioning whether to sit through a movie. Instead, after more than a year of planning, weeks of daily injections, transvaginal ultrasounds, and an egg retrieval, we stood at the cusp of starting a family.

DNA 121
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!