Drug Discovery World
SEPTEMBER 13, 2024
News round-up for 9-13 September by DDW Senior Digital Content Editor Diana Spencer. This week, DDW has opened registrations for its webinar ‘ The latest advancements driving neuroscience drug discovery research ’, so our news highlights focus on developments in neuroscience, including a novel drug that has been shown to reduce neuronal death, and a potential disease-modifying treatment for dementia.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Humans could learn a few medical tips from their gorilla cousins, a new study says.Four plants used by wild gorillas in Gabon have antibacterial and antioxidant properties, researcher reported Sept. 11 in the journal PLOS.
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Drug Discovery World
SEPTEMBER 13, 2024
QL Biopharm, a clinical stage biopharmaceutical company developing biologic drugs for the treatment of metabolic diseases, has shared Phase Ic clinical data for its lead drug candidate ZT002. The data was presented at the European Association for the Study of Diabetes (EASD) Annual Meeting 2024, Madrid, Spain. The presentation was titled ‘ZT002, a novel ultra long-acting GLP-1 receptor agonist in adults with overweight or obesity: A randomised, placebo-controlled, multiple ascending dose Phase I
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Initially approved to treat type 2 diabetes, Ozempic and Mounjaro also can help people with type 1 diabetes lose weight and control their blood sugar levels, a new study finds.Overweight or obese type 1 diabetics taking.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
SEPTEMBER 13, 2024
A Dupixent (dupilumab) pivotal study (ADEPT) in bullous pemphigoid (BP) has met the primary and all key secondary endpoints evaluating its investigational use in adults with moderate-to-severe disease. In the study, five times more Dupixent patients achieved sustained disease remission compared to those on placebo. Sustained disease remission was defined as complete clinical remission with completion of oral corticosteroids (OCS) taper by week 16 without relapse and no rescue therapy use during
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Ozempic and its weight-loss cousin, Wegovy, outperform another longstanding weight-loss drug that targets the same hormone associated with blood sugar and appetite, a new study finds.Ozempic and Wegovy (semaglutide).
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Over 5 million Americans could benefit if the U.S. Food and Drug Administration approves the "magic mushroom" psychedelic psilocybin as a treatment for depression, researchers estimate.“While our analysis is a crucial f.
BioPharma Drive: Drug Pricing
SEPTEMBER 13, 2024
During an investor presentation Thursday, executives admitted to being overly optimistic their vaccine could wrest significant market share away from GSK's and Pfizer's products this year.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Boar's Head announced Friday that its Jarratt, Va. deli meat manufacturing plant, found to be the source of a deadly outbreak of listeria infections, will be closed indefinitely.Boar's Head added that it also believes it.
Fierce BioTech
SEPTEMBER 13, 2024
Navigating today’s rapidly evolving clinical trial landscape can be tough. | With intricate protocols and shifting regulatory demands, it’s more difficult than ever to find and keep participants, as well as gather reliable data.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Florida’s six-week abortion ban caused the state’s abortion rate to drop dramatically, new research shows.Abortions in Florida dropped to an estimated 5,630 in May and 5,200 in June, a 30% and 35% decrease from the average.
Science Daily: Pharmacology News
SEPTEMBER 13, 2024
In a new study, researchers have determined through both statistical analysis and in experiments that soil pH is a driver of microbial community composition -- but that the need to address toxicity released during nitrogen cycling ultimately shapes the final microbial community.
Quanticate
SEPTEMBER 13, 2024
With the implementation of technology rapidly increasing, stricter regulatory standards, and growing demand for innovative treatments, the trends within the industry continue to evolve, impacting the future of clinical trials both positively and negatively. In our article, we cover the key trends that have been shaping clinical trials so far in 2024, and those that are predicted to continue into 2025.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13 , 2024 -- In a case that continues to confound scientists, U.S. health officials said Thursday that they still don't know how a Missouri patient caught the bird flu and that the case may just be a rare anomaly. As bird flu.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
SEPTEMBER 13, 2024
Most rechargeable batteries that power portable devices, such as toys, handheld vacuums and e-bikes, use lithium-ion technology. But these batteries can have short lifetimes and may catch fire when damaged. To address stability and safety issues, researchers have designed a lithium-sulfur (Li-S) battery that features an improved iron sulfide cathode.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Smokers who make the decision to quit will see almost immediate health benefits, including a quick drop in their risk for atrial fibrillation, new research shows.“The findings provide a compelling new reason to show c.
Science Daily: Pharmacology News
SEPTEMBER 13, 2024
A new study reveals that plant-derived secondary organic aerosols (SOAs) can act as mediators of plant-plant interactions. This research was conducted through the cooperation of chemical ecologists, plant ecophysiologists and atmospheric physicists.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- One third of cinnamon products tested by Consumer Reports contained elevated levels of lead, the watchdog agency warned Thursday.The finding follows concerns about metals in foods after tainted cinnamon applesauce poisoned.
Science Daily: Pharmacology News
SEPTEMBER 13, 2024
Physicists propose that a mysterious force known as early dark energy could solve two of the biggest puzzles in cosmology and fill in some major gaps in our understanding of how the early universe evolved.
BioPharma Drive: Drug Pricing
SEPTEMBER 13, 2024
Roche has now beat Merck and Bristol Myers to market with its under-the-skin immunotherapy. Elsewhere, Sanofi bought into radiopharmaceuticals and Mene Pangalos joined Biogen's board.
Science Daily: Pharmacology News
SEPTEMBER 13, 2024
The low-energy excited state of thorium-229 (229Th) isotope nucleus has recently gained much attention owing to it being an ideal candidate for ultra-precise nuclear clocks. Building such high-precision clocks requires an acute understanding of the excitation and de-excitation state of the nucleus. In this view, researchers have designed 229Th-doped vacuum ultraviolet (VUV) transparent CaF2 crystals.
Drug Target Review
SEPTEMBER 13, 2024
In the first article in this series, published Wednesday 14 August, we discussed the importance that data quality plays in the effectiveness of data analyses by Machine Learning (ML) and AI. In part two, we looked at the impact that poor data quality can have on ML models. Here, we outline 15 pragmatic guidelines to ensure better data quality in early drug discovery and to identify potential issues with compromised data.
Fierce BioTech
SEPTEMBER 13, 2024
Leveraging Whole-Genome Sequencing for Advanced Drug Discovery pesurya Fri, 09/13/2024 - 11:18 Wed, 10/23/2024 - 11:00 Resource Type Webinar Keren Carss Joseph Maranville Dirk Paul Leeland Ekstrom Geoff Nilsen Duration 60 Minutes Large, deeply characterized patient cohorts are one of the most promising resources today for understanding disease biology and developing new medicines.
Perficient: Drug Development
SEPTEMBER 13, 2024
Technical Challenge The key idea of proposed approach is to create an instance with two databases attached: Sitecore 9 Legacy New Sitecore 10 XM Cloud There could be two potential ways of doing this: Restore backup of XM Cloud database to a legacy XP of the desired version with content databased already attached/restored. That would not works since XP 9.3 neither knows about XM Cloud schema, nor is capable to handle Items as Resource which were invented in XP 10.1.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Fear of a having a low blood sugar crash dissuades many people with type 1 diabetes from getting the exercise they need, a new study finds.However, people were more likely to engage in exercise if their doctor discussed.
Perficient: Drug Development
SEPTEMBER 13, 2024
The greatest wealth is health. Perficient came up with this “wellness at work, wellness in life” initiative to provide basic health care, Eye care and dental care to its employees. Perficient proves its value for People and prioritized the wellness of its people. Perficient joined hands with Kauvery hospital for basic health care, Dr Agarwal’s hospital for eye care and Clove dental for dental care.
Drugs.com
SEPTEMBER 13, 2024
FRIDAY, Sept. 13, 2024 -- Excessive time spent on social media increases children's and teens’ risk of developing an eating disorder, a new study warns.Each additional hour of total screen time or social media use raises the likelihood that a kid o.
Drug Channels
SEPTEMBER 13, 2024
Today’s guest post comes from Rick Fry, VP of Strategic Development at GoodRx. Rick explains why patients and pharmaceutical manufacturers now pay a greater share of prescription costs. He outlines GoodRx's services that address the twin challenges when the patient is the payer and the manufacturer faces intense gross-to-net pressures. To learn more, download the GoodRx case study: GoodRx Integrated Platform Solutions: Patient Navigator + Integrated Copay Card.
New Drug Approvals
SEPTEMBER 13, 2024
ATICAPRANT JNJ-67953964 , WHO 10582 1174130-61-0 BENZAMIDE, 4-(4-(((2S)-2-(3,5-DIMETHYLPHENYL)-1-PYRROLIDINYL)METHYL)PHENOXY)-3-FLUORO- C 26 H 27 FN 2 O 2 , 418.512 4-[4-[[(2 S )-2-(3,5-Dimethylphenyl)-1-pyrrolidinyl]methyl]phenoxy]-3-fluorobenzamide (ACI) ( S )-4-(4-((2-(3,5-Dimethylphenyl)pyrrolidin-1-yl)methyl)phenoxy)-3-fluorobenzamide 4-(4-{[(2 S )-2-(3,5-dimethylphenyl)pyrrolidin-1-yl]methyl}phenoxy)-3-fluorobenzamide Aticaprant CERC 501 JNJ 67953964 JNJ 67953964AAA LY 2456302 S -Aticapran
Fierce BioTech
SEPTEMBER 13, 2024
Highlights From the Final ICH Drug Interactions Guideline pesurya Fri, 09/13/2024 - 11:39 Thu, 10/31/2024 - 11:00 Resource Type Webinar Brian Ogilvie Graham Dyck Duration 60 Minutes The ICH M12 Guideline was finalized on May 21st, 2024, after extensive review of industry and other comments. The Guideline was the culmination of the extensive work by the Expert Working Group.
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