Science Daily: Pharmacology News
FEBRUARY 11, 2025
Scientists have developed new light-sensitive chemicals that can radically improve the treatment of aggressive cancers with minimal side effects. In mouse tests, the new therapy completely eradicated metastatic breast cancer tumors.
Drugs.com
FEBRUARY 11, 2025
TUESDAY, Feb. 11, 2025 -- Ozempic, Wegovy, Saxenda, Trulicity: These and other GLP1-RA diabetes/weight-loss meds can also boost outcomes for folks battling chronic kidney disease, new research shows.Compared to another common class of kidney.
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Science Daily: Pharmacology News
FEBRUARY 11, 2025
An international research team has gained new insights into the burial rituals of Late Ice Age societies in Central Europe. Signs of human remains from the Maszycka Cave in southern Poland being manipulated indicate systematic dissection of the deceased, as well as cannibalism.
Drugs.com
FEBRUARY 11, 2025
TUESDAY, Feb. 11, 2025 -- More than 800,000 U.S. children have what's called "high threshold" peanut allergy, meaning they can tolerate about half a peanut daily before symptoms arise.New research suggests that exposing these kids to tiny but.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
FEBRUARY 11, 2025
Answer seven questions and get an indication of how your relationship is right now. Just in time for Valentine's Day, researchers are publishing a new study that introduces a scientifically validated scale, the 'Valentine's Scale'. The scale measures how satisfied you are in your love relationship.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
FEBRUARY 11, 2025
New research reports, for the first time, the widespread occurrence of biofluorescence in birds-of-paradise. The study, based on specimens collected since the 1800s, finds biofluorescence in 37 of the 45 known birds-of-paradise species and suggests that this special 'glow' is important among males for hierarchy and mating displays.
Drugs.com
FEBRUARY 11, 2025
TUESDAY, Feb. 11, 2025 -- The U.S. Food and Drug Administration is urging all patients with smartphone-compatible diabetes devices to check their phone configurations to ensure all safety alerts are being received.The FDA notice concerns continuous.
Drug Patent Watch
FEBRUARY 11, 2025
The Dark Side of Innovation: How Companies Use Drug Patents to Block Competitors As we celebrate the breakthroughs in medical research and the development of life-saving treatments, it's essential to acknowledge the complex landscape of pharmaceutical innovation. Behind the scenes, companies are employing clever tactics to protect their intellectual property and block competitors from entering the market.
Drugs.com
FEBRUARY 11, 2025
TUESDAY, Feb. 11, 2025 -- During the week of Jan. 26 through Feb. 1, 2025, flu activity remained elevated in the United States, with 43 states reporting high or very high outpatient respiratory illness activity, according to FluView, a weekly.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
FEBRUARY 11, 2025
The acquisition of Anthos Therapeutics could be worth up to $3.1 billion and returns to Novartis a blood thinner it licensed to the Blackstone-backed startup six years ago.
Science Daily: Pharmacology News
FEBRUARY 11, 2025
In 2018, the side of the Anak Krakatau volcano collapsed in a powerful eruption and produced a tsunami that killed hundreds and injured thousands on nearby Java and Sumatra in Indonesia. A new analysis of satellite data showed the mountainside was slipping for years and accelerated before the eruption -- information that could have potentially offered a warning of the collapse.
Drugs.com
FEBRUARY 11, 2025
TUESDAY, Feb. 11, 2025 -- Want to thrive in tough, stressful times? Stay playful.That's the take-home message from a new study of who fared best, in terms of mental resiliency, during the COVID-19 pandemic. The researchers said the findings have.
addgene Blog
FEBRUARY 11, 2025
The versatility of CRISPR allows you to play with DNA in a number of ways, from small edits that change single base pairs, to chromosomal inversions and large deletions. Many of these methods rely on Cas9 or a derivative of Cas9, but the ever-expanding repertoire of CRISPR has brought many other Cas effectors to light.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
FEBRUARY 11, 2025
TUESDAY, Feb. 11, 2025 -- Chronic ills like heart disease, asthma or diabetes afflict a majority of U.S. workers, but 60% of those affected say they've kept their health issue a secret from employers, a new poll finds.More than a third of workers.
Broad Institute
FEBRUARY 11, 2025
Broad Discovery Series: Introducing the immune system, and expanding its cancer-fighting potential By admin February 11, 2025 Breadcrumb Home Broad Discovery Series: Introducing the immune system, and expanding its cancer-fighting potential Lloyd Bod Associate Member Broad Institute Principal investigator Krantz Family Center for Cancer Research Massachusetts General Hospital Assistant Professor of Medicine Harvard Medical School The immune system's immense variety of cells and tissues all play
Drugs.com
FEBRUARY 11, 2025
TUESDAY, Feb. 11, 2025 -- It was a bit safer to go into the water last year: Unprovoked shark attacks worldwide fell by about a third in 2024 compared to the year before, new data show.The United States continues to be the most likely country in.
Broad Institute
FEBRUARY 11, 2025
Mapping mRNA through its life cycle within a cell By Corie Lok February 11, 2025 Breadcrumb Home Mapping mRNA through its life cycle within a cell Xiao Wangs studies of how and where RNA is translated could lead to the development of better RNA therapeutics and vaccines. By Anne Trafton, MIT News February 11, 2025 Credit: Jodi Hilton Xiao Wang is a core institute member at the Broad Institute.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
DS in Pharmatics
FEBRUARY 11, 2025
Learn how to prepare for FDA inspections, engage with inspectors, and respond to findings with expert support from DS InPharmatics.
BMG Labtech
FEBRUARY 11, 2025
What is protein nitration? Nitration can significantly modify the structure and function of proteins in cells. But how can measurements of protein nitration reveal crucial information about biological activity and how do microplate readers contribute?
BioPharma Drive: Drug Pricing
FEBRUARY 11, 2025
The German drugmaker confirmed acquisition talks, but cautioned a deal may not materialize. Elsewhere, Biohaven got priority review on a key drug and Third Harmonic restructured.
Science Daily: Pharmacology News
FEBRUARY 11, 2025
Qubits -- the fundamental units of quantum information -- drive entire tech sectors. Among them, superconducting qubits could be instrumental in building a large-scale quantum computer, but they rely on electrical signals and are difficult to scale. In a breakthrough, a team of physicists has achieved a fully optical readout of superconducting qubits, pushing the technology beyond its current limitations.
Chemical Biology and Drug Design
FEBRUARY 11, 2025
Baicalein inhibited the tumor property of HCC cells through the inactivation of the E2F1/MED7 axis, highlighting its potential clinical application in the treatment of HCC. ABSTRACT Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with poor prognosis. Baicalein, a natural compound, can regulate multiple cellular processes in various cancer types.
Perficient: Drug Development
FEBRUARY 11, 2025
In this blog post, I will guide you through the process of implementing a Spring Expression Language (SpEL) validator in a Spring Boot application. SpEL is a powerful expression language that supports querying and manipulating an object graph at runtime. By the end of this tutorial, you will have a working example of using SpEL for validation in your Spring Boot application.
FDA Law Blog: Biosimilars
FEBRUARY 11, 2025
By Alan M. Kirschenbaum & Sophia R. Gaulkin Drug manufacturers wont be receiving their first invoices for Medicare Part B and Part D inflation rebates until later this year, but rebates have been accruing since first quarter 2023 for Part B rebates and October 2022 for Part D rebates. To help our readers learn more about these rebates before they confront the first invoices, weve prepared a memo summarizing CMS final rule on the two Medicare inflation rebate programs, which was issued on De
FDA Law Blog: Drug Discovery
FEBRUARY 11, 2025
By Mark A. Tobolowsky & Frank J. Sasinowski The rare pediatric disease priority review voucher program remains in its sunsetting state the current authority only allows for granting of such vouchers if the drug was designated as a drug for a rare pediatric disease not later than December 20, 2024, and for which a rare pediatric disease product application is approved not later than September 30, 2026.
FDA Law Blog: Biosimilars
FEBRUARY 11, 2025
By Larry K. Houck One of the most significant issues facing hospitals and other facilities is the diversion of controlled substances meant for patients by physicians, pharmacists, nurses and other trusted healthcare employees. Recent employee diversion of significant controlled substance quantities from hospitals has resulted in large civil monetary settlements, some in the millions of dollars, and costly compliance remediation programs to resolve allegations.
Drug Target Review
FEBRUARY 11, 2025
Drug development: addressing complexity and success rates Drug development is a complex and expensive process, requiring multidisciplinary expertise and high-risk financial investments. The major hurdles that pharmaceutical companies face are long lead times, high costs and a low probability of success (PoS). These hurdles not only delay patient access to innovative treatments but also threaten the economic sustainability of research and development (R&D) and the advancement of medical innov
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