Fri.Jun 06, 2025

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Long-Lasting HIV Prevention Shot Headed Toward Approval

Drugs.com

FRIDAY, June 6, 2025 — A new injection to prevent HIV is expected to be approved by the U.S. Food and Drug Administration (FDA) later this month. If approved, the shot — lenacapavir — would be given twice a year and could be a big.

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Otsuka tops Vera with kidney drug data; Regenxbio sinks on Duchenne update

BioPharma Drive: Drug Pricing

Late-stage results Otsuka presented in IgA nephropathy triggered a sell-off in Vera shares. Elsewhere, investors scrutinized Regenxbio’s Duchenne data and a brain drug study failed.

Drugs 221
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Diabetes Drug, Dapagliflozin, Effective For Fatty Liver Disease

Drugs.com

FRIDAY, June 6, 2025 — A repurposed diabetes drug can be an effective tool against fatty liver disease, a new clinical trial has found. Dapagliflozin helped people reduce fat levels in their liver and avoid liver scarring that comes with the.

Disease 244
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FDA meeting gives window into gene therapy field’s angst

BioPharma Drive: Drug Pricing

Gene therapy experts and advocates warning of the sector’s many challenges found a receptive audience in FDA leadership at a regulatory forum Thursday.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Immunotherapy Effective Against Stomach Cancer

Drugs.com

FRIDAY, June 6, 2025 — Immunotherapy combined with chemo can give people a fighting chance against stomach and esophageal cancers, a new clinical trial says.People treated with durvalumab and chemotherapy were much more likely to go into remission.

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Diabetes Drug Effective For Fatty Liver Disease

Drugs.com

FRIDAY, June 6, 2025 — A repurposed diabetes drug can be an effective tool against fatty liver disease, a new clinical trial has found.Dapagliflozin helped people reduce fat levels in their liver and avoid liver scarring that comes with the c.

Disease 244
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Largest-ever map of the universe reveals 10x more early galaxies than expected

Science Daily: Pharmacology News

An international team of scientists has unveiled the largest and most detailed map of the universe ever created using the James Webb Space Telescope, revealing nearly 800,000 galaxies stretching back to almost the beginning of time. The COSMOS-Web project not only challenges long-held beliefs about galaxy formation in the early universe but also unexpectedly revealed 10 times more galaxies than anticipated along with supermassive black holes Hubble couldn t see.

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There's A Better Clot-Preventing Option Than Aspirin, Researchers Say

Drugs.com

FRIDAY, June 6, 2025 — There’s a better option than daily aspirin to protect heart patients with a stent against dangerous blood clots, a new study found.A class of drugs called P2Y12 inhibitors that includes ticagrelor and clopidogrel could be mor.

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Why radiopharmaceuticals are gaining ground in the fight against cancer

Drug Target Review

In recent years, the field of nuclear medicine has undergone a quiet revolution, particularly in its application to oncology. At the forefront of this transformation is Dr Ebrahim Delpassand, a nuclear medicine physician and the driving force behind RadioMedix (RMX), a radiopharmaceutical company focused on developing targeted diagnostics and therapies.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Freshwater U.S. Fish Carry Parasitic Flatworm That Can Infect Humans

Drugs.com

FRIDAY, June 6, 2025 — Freshwater game fish like bluegill, largemouth bass and black crappie in the U.S. commonly carry parasitic flatworms that can infect humans, a new study warns.More than 90% of popular game fish tested in Southern California c.

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Scientists uncover 230 giant ocean viruses that hijack photosynthesis

Science Daily: Pharmacology News

Scientists have uncovered over 200 new giant viruses lurking in ocean waters that not only help shape marine ecosystems but also manipulate photosynthesis in algae. These massive viruses once nearly invisible to science are now being exposed using powerful supercomputing and a new tool called BEREN. By studying these viruses, researchers hope to predict harmful algal blooms and even explore biotech applications from the novel enzymes found in these viral genomes.

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FDA Authorizes First AI Platform for Breast Cancer Prediction

Drugs.com

FRIDAY, June 6, 2025 -- The U.S. Food and Drug Administration has granted de novo authorization to CLAIRITY BREAST, a first-in-class, image-based platform that can help predict a woman's risk for breast cancer. CLAIRITY BREAST is designed as a.

FDA 165
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Shifting the ADC focus from antibody to payload

Drug Target Review

As antibody-drug conjugates (ADCs) gain traction across oncology and begin to expand into other therapeutic areas, a persistent challenge remains: the design and optimisation of payloads. Across Sygnature Discovery , multidisciplinary teams in Canada and the UK are actively working to address these challenges. With an extensive background in small molecule chemistry, bioconjugation and protein science, these expert teams are leading efforts to place payload development at the centre of ADC innov

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Case Study: Two Examples of Successful Automation Integration at Altasciences for Pharmacokinetic Studies

Alta Sciences

Case Study: Two Examples of Successful Automation Integration at Altasciences for Pharmacokinetic Studies pmjackson Fri, 06/06/2025 - 09:01 By Martin Rougée, Optimization Scientist, Bioanalytical Operations Automation offers several advantages to any industry. For a contract research organization (CRO), it can play an integral role in increasing the quality and speed of drug development while reducing costs, repetitive manual tasks, and human error.

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Teenage 'Night Owls' More Likely To Act Impulsively

Drugs.com

FRIDAY, June 6, 2025 — Teenagers who are night owls appear to be more self-destructively impulsive, a new study says.Teens who prefer to sleep and wake later are more impulsive than “early bird” teenagers, researchers are scheduled to report at the.

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Biocatalytic paths to synthesis of Iptacopan metabolites

Metabolite Tales Blog

Biocatalytic paths to the synthesis of selected metabolites of Iptacopan In a recent paper published in celebration of the 20th birthday of the Swiss Industrial Biocatalysis Consortium, various applications of industrial biocatalysis were described [1]. One example from Novartis highlighted the production of analytical reference standards to access metabolites of Iptacopan (Fabhalta®) to support human ADME studies.

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From Discovery to Discontinuation: How Medical Information Supports Every Stage

thought leadership

The journey from compound discovery to market-ready pharmaceutical product is long, complex, and resource-intensive. Only about 1 in 5,000 drug candidates make it to patients 1 , underscoring the need for robust strategies at every stage of development. Medical Information (MI) services are instrumental Product Lifecycle Management (PLM) —ensuring safety, efficacy, and compliance while driving value and maintaining a patient-centric focus.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Vertex Highlights ALYFTREK® Data and Sweat Chloride Goals at European CF Conference

The Pharma Data

Vertex Showcases Robust Clinical Data Supporting ALYFTREK® and the Critical Role of Sweat Chloride Reduction at 2025 European Cystic Fibrosis Conference New findings reinforce the value of CFTR modulation and the potential of ALYFTREK to enhance health outcomes and quality of life in cystic fibrosis patients Vertex Pharmaceuticals Incorporated, a global biotechnology leader in cystic fibrosis (CF) research and treatment innovation, presented a comprehensive body of new data at the 48th European

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AI and Human Collaboration in UX Design

Perficient: Drug Development

Artificial Intelligence (AI) is rapidly transforming the landscape of User Experience (UX) in digital design. From automating interface elements to delivering personalized content, AI has become a reliable tool for improving the efficiency, adaptability, and relevance of digital experiences. Despite these advancements, the role of human designers remains vital—especially where creativity, empathy, and ethical decision-making are concerned.

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Otsuka’s Sibeprenlimab Shows Significant Proteinuria Reduction in Phase 3 IgAN Trial

The Pharma Data

Otsuka Unveils Promising Phase 3 Results for Sibeprenlimab in IgA Nephropathy, Marking Significant Proteinuria Reduction and Advancing a Novel APRIL-Targeted Therapy Otsuka Pharmaceutical Development & Commercialization, Inc., in collaboration with Otsuka Pharmaceutical Co., Ltd., has announced encouraging interim findings from the pivotal Phase 3 VISIONARY trial evaluating sibeprenlimab in adults with Immunoglobulin A nephropathy (IgAN), a rare and progressive autoimmune kidney disorder.

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Salesforce Health Check Assessment Unlocks ROI

Perficient: Drug Development

How Salesforce Turns from Catalyst to Constraint At a time when agility and efficiency are the new currency of business, your Salesforce org should be your most powerful asset—not a tangled web of technical debt, short-term workarounds, and outdated architecture. Yet many companies are feeling the strain. Customizations are built in silos New functionality gets bolted on without long-term planning Reporting becomes a nightmare Instead of accelerating business, Salesforce becomes something te

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Sanofi Showcases Rare Disease Pipeline Innovations at ISTH

The Pharma Data

Sanofi Highlights Robust Pipeline of Innovations in Rare Blood Disorders at ISTH 2025 Sanofi is poised to take center stage at the 33rd Congress of the International Society on Thrombosis and Haemostasis (ISTH), set to be held in Washington, D.C., from June 21 to 25, 2025. At this premier global meeting focused on thrombosis, hemostasis, and bleeding disorders, Sanofi will present compelling data across 18 scientific abstracts, including five oral presentations.

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Mastering Databricks Jobs API: Build and Orchestrate Complex Data Pipelines

Perficient: Drug Development

In this post, we’ll dive into orchestrating data pipelines with the Databricks Jobs API, empowering you to automate, monitor, and scale workflows seamlessly within the Databricks platform. Why Orchestrate with Databricks Jobs API? When data pipelines become complex involving multiple steps—like running notebooks, updating Delta tables, or training machine learning models—you need a reliable way to automate and manage them with ease.

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JCR Pharmaceuticals Celebrates 50 Years with Unique Global Website Launch

The Pharma Data

JCR Pharmaceuticals Celebrates 50 Years of Innovation with Global Website Launch That Reflects Its Expanding Reach and Human-Centric Mission As JCR Pharmaceuticals commemorates its 50th anniversary, the global specialty biopharmaceutical company is marking this major milestone with the launch of a newly designed global website. More than just a digital upgrade, the website represents the company’s transformation from a pioneering Japanese biotech startup into a global force in the field of

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How to Add Product Badges in Optimizely Configured Commerce Spire

Perficient: Drug Development

This blog is written for developers, merchandisers, or client teams looking to display visual indicators (e.g., “New”, “Sale”, “Non-Returnable”, “Best Seller”) on products within the storefront. In Ecommerce, badges are small visual cues that communicate important product information to customers, such as “New Arrival”, “Sale”, or “Limited Stock”. In Optimizely Configured Commerce (Spire) , product badges can be a powerful way to highlight key promotions or product statuses, thereby improving th

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Pharma Contract Sales Outlook 2025–2030: Multilingual Teams Drive Global Expansion

The Pharma Data

Global Pharmaceutical Contract Sales Outsourcing Market to Reach $24.8 Billion by 2030: Strategic Insights, Regional Trends, and Technological Shifts Reshaping the Landscape The global pharmaceutical contract sales outsourcing (CSO) market is entering a transformative phase, with its value expected to grow from $17.3 billion in 2024 to $24.8 billion by 2030 , reflecting a compound annual growth rate (CAGR) of 6.2%.

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Simplify Cloud-Native Development with Quarkus Extensions

Perficient: Drug Development

The gradients that developers in the modern world experience when building cloud native applications often include the challenge of figuring out the right set of libraries and integrations to use. Quarkus alleviates this pain point and makes this experience a more seamless and faster experience to develop thanks to the rich set of extensions built into the Quarkus ecosystem.

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Moving Beyond Mitigation: Cracking the Maximizer Code to Protect Patient Affordability

Drug Channels

Today’s guest post comes from Logan Melchione, VP of Patient Affordability at Paysign. Logan explores how maximizers have reshaped the patient affordability landscape and pressured pharmaceutical manufacturers to adapt their copay strategies. In this guest post, she outlines her perspective on the limitations of traditional copay solutions, describes Paysign’s data-driven approach to first-fill identification of maximizer impact, and shares how the company reports saving millions while improving

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Strategy for Addressing Specificity Challenges in Quantitation of Etonogestrel in Human Plasma by LC-MS/MS

Alta Sciences

Strategy for Addressing Specificity Challenges in Quantitation of Etonogestrel in Human Plasma by LC-MS/MS iianiro Fri, 06/06/2025 - 09:00 Publication Poster_Altasciences_ASMS_2025_Strategy_for_Addressing_Specificity_Challenges_in_Quantitation_of_Etonogestrel_in_Human_Plasma.

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