Fri.Nov 08, 2024

article thumbnail

Science Reveals Why Cancer Immunotherapies Can Sometimes Harm the Heart

Drugs.com

FRIDAY, Nov. 8, 2024 -- Researchers think they’ve figured out why cancer treatments that harness a person’s immune system to fight a tumor can cause heart damage in rare instances.Further, what they’ve learned sheds light on how this potentially dea.

Science 116
article thumbnail

Chimpanzees perform better on challenging computer tasks when they have an audience

Science Daily: Pharmacology News

When people have an audience watching them, it can change their performance for better or worse. Now, researchers have found that chimpanzees' performance on computer tasks is influenced by the number of people watching them. The findings suggest that this 'audience effect' predates the development of reputation-based human societies, the researchers say.

Research 115
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Complications From Prostate Cancer Therapy Can Be Serious and Long-Term

Drugs.com

THURSDAY, Nov. 7, 2024 -- Men who undergo prostate cancer treatment face a greatly increased risk of life-altering, long-term complications, a new study finds.Surgery for prostate cancers increases a man’s risk of urinary or sexual complications m.

Therapies 111
article thumbnail

Elephant turns a hose into a sophisticated showering tool

Science Daily: Pharmacology News

Tool use isn't unique to humans. Chimpanzees use sticks as tools. Dolphins, crows, and elephants are known for their tool-use abilities, too. Now a report highlights elephants' remarkable skill in using a hose as a flexible shower head. As an unexpected bonus, researchers say they also have evidence that a fellow elephant knows how to turn the water off, perhaps as a kind of 'prank.

Research 114
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

1 in 5 People Could Have Long COVID

Drugs.com

FRIDAY, Nov. 8, 2024 -- More than 1 in 5 Americans likely suffer from long COVID, a new AI-assisted review has found. The analysis suggests that nearly 23% of U.S. adults experience the symptoms of long COVID, according to results published Nov. 8.

105
105
article thumbnail

Deep ocean clues to a million-year-old ice age puzzle revealed in new study

Science Daily: Pharmacology News

A new study challenges theories regarding the origins of a significant transition through the Earth's ice ages. The research provides fresh insights into the ocean's role in climate during the Mid-Pleistocene Transition, an enigmatic interval of change in climate cycles that began about one million years ago.

Research 106

More Trending

article thumbnail

Mitochondria Are Alive

Codon

An opinion essay by Liyam Chitayat The cells within our body are the remnants of an ancient alliance. In a 1967 paper called “ On the Origin of Mitosing Cells ,” American evolutionary biologist Lynn Margulis proposed an idea that, upon first hearing, seems ludicrous. Her paper, in fact, was rejected by 12 different journals before it was published.

DNA 142
article thumbnail

1 in 4 Moms Fall Asleep While Breastfeeding, Putting Babies at Risk for SIDS

Drugs.com

FRIDAY, Nov. 8, 2024 -- A new study finds that a quarter of (no doubt exhausted) breastfeeding moms admit to falling asleep while their baby was feeding, a moment that can raise risks for infant suffocation.That's because whenever a baby falls.

98
article thumbnail

Scarlet Macaw parents 'play favorites,' purposefully neglect younger chicks

Science Daily: Pharmacology News

Researchers have discovered that scarlet macaws purposefully neglect feeding the youngest chicks in most broods, even when resources are plentiful. This results in only one or two chicks being able to fledge -- the process in which parents teach their young to fly and survive on their own -- even though broods may contain up to four chicks.

article thumbnail

Athira exploring strategic alternatives after Alzheimer’s failure

BioPharma Drive: Drug Pricing

On the heels of its most advanced medicine flunking a key study, the drugmaker is looking at the different paths it could take to “maximizing stockholder value.

65
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Childbirth Can Bring Worrying Medical Bills, Even With Insurance

Drugs.com

FRIDAY, Nov. 8, 2024 -- Having a child can cause significant and ongoing financial hardship for new parents, even if they are covered by health insurance, a new study shows.More than half of people with private insurance spent more than $1,000 out.

64
article thumbnail

Tezspire succeeds in chronic rhinosinusitis; Gilead writes down Trodelvy value

BioPharma Drive: Drug Pricing

AstraZeneca and Amgen's drug could have a new use after positive Phase 3 study results. Elsewhere, Jazz set new plans for a narcolepsy drug and CDMO Avid Bioservices agreed to be taken private.

Drugs 61
article thumbnail

Target Ligand Separation and Identification of Isoforsythiaside as a Histone Lysine-Specific Demethylase 1 Covalent Inhibitor Against Breast Cancer Metastasis

Covalent Modifiers

Mengzhen Gu, Xiaoqing Xu, Xiaoping Wang, Yun Wang, Yu Zhao, Xiaoxian Hu, Lu Zhu, Zhenzhong Deng, and Chao Han Journal of Medicinal Chemistry 2024 DOI: 10.1021/acs.jmedchem.4c02277 Histone lysine-specific demethylase 1 (LSD1) is hyperactive in breast cancer, which is associated with the metastasis of the tumor. Current irreversible LSD1 inhibitors are all synthesized by covalently binding to the flavin adenine dinucleotide cofactor, which often have side effects due to the high affinity for a var

article thumbnail

Kalaris to go public via reverse merger with AlloVir

BioPharma Drive: Drug Pricing

After Kalaris and AlloVir combine, the new company will have about $100 million to advance a treatment for age-related macular degeneration.

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Being Born Preterm Tied to Lifelong Harms in Employment, Education

Drugs.com

FRIDAY, Nov. 8, 2024 -- Babies born preterm face a life of lowered prospects, a new study warns.Adults who were preemies are less likely to achieve higher education or snag a high-paying job, researchers reported Nov. 6 in the journal PLOS.

article thumbnail

Qualification of a Veterinary Glucometer for Use in Yucatan Miniature Swine

Alta Sciences

Qualification of a Veterinary Glucometer for Use in Yucatan Miniature Swine lperez Fri, 11/08/2024 - 17:58 Publication Poster_Altasciences_AALAS2024_Qualification_of_a_Veterinary_Glucometer_for_Use_in_Yucatan_Miniature_Swine.

article thumbnail

Why Universal Design for Cognitive Disabilities in Healthcare Matters

Perficient: Drug Development

Promotes Equality and Inclusivity Universal design ensures that all patients, regardless of their cognitive abilities, have equal access to healthcare services. This promotes an inclusive healthcare environment where everyone feels valued and respected. By removing barriers, healthcare providers can offer equitable care to all individuals. Enhances Patient Understanding and Compliance Clear communication and supportive environments help patients with cognitive disabilities understand their healt

article thumbnail

Women Can Incur 'Catastrophic' Bills for Out-of-State Abortions, Study Finds

Drugs.com

FRIDAY, Nov. 8, 2024 -- One piece left out of the abortion debate is the high transportation and medical bills facing women forced to leave their state to obtain the procedure. A new study is the first to give hard numbers on those concerns. It.

97
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

AI Regulations for Financial Services: Federal Reserve

Perficient: Drug Development

Artificial intelligence (AI) is poised to affect every aspect of the world economy and play a significant role in the global financial system, leading financial regulators around the world to take various steps to address the impact of AI on their areas of responsibility. The economic risks of AI to the financial systems include everything from the potential for consumer and institutional fraud to algorithmic discrimination and AI-enabled cybersecurity risks.

article thumbnail

What RFK Jr.’s influence on Trump could mean for pharma

BioPharma Drive: Drug Pricing

Past comments by Robert F. Kennedy Jr. hint at the ideas he might advocate if given a role in the incoming Trump administration.

112
112
article thumbnail

New insights into the Denisovans: New hominin group that interbred with modern day humans

Science Daily: Pharmacology News

Scientists believe individuals of the most recently discovered 'hominin' group (the Denisovans) that interbred with modern day humans passed on some of their genes via multiple, distinct interbreeding events that helped shape early human history. Scientists outline evidence suggesting that several Denisovan populations, who likely had an extensive geographical range from Siberia to Southeast Asia and from Oceania to South America, were adapted to distinct environments.

139
139
article thumbnail

Sexual Victimization Allegations Reported by Administrators in Adult Correctional Facilities

Common Sense for Drug Policy Blog

Sexual Victimization Allegations Reported by Administrators in Adult Correctional Facilities "In 2020, correctional administrators reported 36,264 allegations of sexual victimization in prisons, jails, and other adult correctional facilities (figure 1). This included allegations of inmate-on-inmate nonconsensual sexual acts, inmate-on-inmate abusive sexual contact, inmateon-inmate sexual harassment, staff-on-inmate sexual misconduct, and staff-on-inmate sexual harassment.1 Of all the allegations

52
article thumbnail

Genome-Wide Association Studies (GWAS): A Refreshed Perspective

Broad Institute

Genome-Wide Association Studies (GWAS): A Refreshed Perspective By Maria Nemchuk November 8, 2024 Genome-Wide Association Studies (GWAS): A Refreshed Perspective Alisa Manning Massachusetts General Hospital Harvard Medical School Broad Institute Talks Search - Any - Fall 2024 Spring 2024 Fall 2023 Spring 2023 Fall 2022 Spring 2022 Fall 2021 Spring 2021 Fall 2020 Spring 2020 Fall 2019 Spring 2019 Fall 2018 Spring 2018 Fall 2017 Spring 2017 Fall 2016 Spring 2016 Fall 2015 Summer 2015 Spring 2015 S

article thumbnail

Sexual Victimization Reported by Youth in US Juvenile Correctional Facilities

Common Sense for Drug Policy Blog

Sexual Victimization Reported by Youth in US Juvenile Correctional Facilities "In 2018, 4.0% of youth in juvenile facilities reported sexual victimization that involved force or coercion, either by another youth or by facility staff (not shown in tables). An estimated 1.9% of youth reported sexual victimization involving force or coercion by another youth (table 1).

52
article thumbnail

Sexual Victimization of Youth by Staff in Juvenile Correctional Facilities in the US

Common Sense for Drug Policy Blog

Sexual Victimization of Youth by Staff in Juvenile Correctional Facilities in the US "In 2018, an estimated 2.1% of youth reported that they were sexually victimized by staff through force or coercion. Forced or coerced sexual acts or other sexual activity with facility staff included sexual activity involving physical force, threat of force, or other forms of pressure or coercion, such as being given money, favors, protection, or special treatment or being repeatedly asked to engage in sexual a