Sat.May 10, 2025 - Fri.May 16, 2025

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Boosters and Biologics: Is Space-Based Biomanufacturing Real?

LifeSciVC

By Cody Tranbarger, EIR at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Its an interesting time to be thinking about space. Just a few months ago, SpaceX captivated and inspired the world by catching a reusable rocket booster with mechanical chopsticks for the first time. Meanwhile, humanitys march toward a multi-planetary future continues, with Mars on the itinerary for the 2030s (unless youre on Elon time ).

Science 97
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Genome of near-extinct northern white rhino offers hope for reviving the species

Science Daily: Pharmacology News

The northern white rhinoceros is one of the rarest animals on Earth, with just two females left and no natural way for the species to reproduce. Now, scientists have mapped the entire genome of a northern white rhino. This represents a crucial step toward bringing the critically endangered species back from the edge using advanced reproductive technologies.

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Ubrogepant (Ubrelvy) Effective Against Early Migraine Symptoms

Drugs.com

WEDNESDAY, May 14, 2025 -- Migraines don’t just cause headaches. These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness. What’s more, those non-headache symptoms tend to crop.

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GSK to buy liver disease drug for $1.2B

BioPharma Drive: Drug Pricing

The new acquisition from Boston Pharmaceuticals adds to a wave of dealmaking undertaken by GSK to build its liver disease franchise.

Disease 260
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Synthesis Methods and Therapeutic Journey of Carprofen and Its Derivatives: A Review

Chemical Biology and Drug Design

Although it is currently only used in veterinary therapy, carprofen proves to be a molecule with a versatile therapeutic potential for human pharmacotherapy. Moreover, the molecule is a target in the drug discovery process for the development of new bioactive compounds. ABSTRACT Carprofen, a nonsteroidal anti-inflammatory drug (NSAID) derived from propanoic acid, is known for its analgesic and antipyretic properties.

More Trending

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Alzheimer’s Drug, Leqembi, Can Be Safely Administered In Memory Clinics, Study Says

Drugs.com

THURSDAY, May 15, 2025 — The 2023 approval of the first drug shown to slow the progression of Alzheimer’s disease came with no small amount of concern from skeptics. Lecanemab (Leqembi) modestly slows Alzheimer’s by helping the.

Drugs 275
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Abeona sells speedy drug review voucher for $155M

BioPharma Drive: Drug Pricing

The biotech has quickly turned a cell therapy approval into one of the more lucrative recent sales for a priority review voucher, which companies can use to fast track drug reviews.

Drugs 282
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Current Challenges With Highly Active Antiretroviral Therapy and New Hope and Horizon With CRISPR‐CAS9 Technology for HIV Treatment

Chemical Biology and Drug Design

CRISPR-CAS9 is an innovative gene editing technology to precisely remove or incorporate into the gene of interest; CRISPR-CAS9 shows promising results in HIV treatment. ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR/Cas system) is now the predominant approach for genome editing. Compared to conventional genetic editing methods, CRISPR/Cas technology offers several advantages that were previously unavailable.

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Infant with rare, incurable disease is first to successfully receive personalized gene therapy treatment

Science Daily: Pharmacology News

A research team has developed and safely delivered a personalized gene editing therapy to treat an infant with a life-threatening, incurable genetic disease. The infant, who was diagnosed with the rare condition carbamoyl phosphate synthetase 1 (CPS1) deficiency shortly after birth, has responded positively to the treatment. The process, from diagnosis to treatment, took only six months and marks the first time the technology has been successfully deployed to treat a human patient.

Treatment 285
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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More U.S. Teens Getting Weight-Loss Surgery

Drugs.com

WEDNESDAY, May 14, 2025 More U.S. teenagers are getting weight-loss surgery, despite the discovery of new drugs like Ozempic/Wegovy that help people drop pounds surgery-free, a new study says.Weight loss surgeries for teens increased 15% between 2.

Drugs 243
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Novo to work with Septerna in hunt for oral obesity drugs

BioPharma Drive: Drug Pricing

The research collaboration, under which Septerna will receive more than $200 million in upfront and near-term fees, is the latest deal Novo has struck to expand its obesity pipeline.

Drugs 157
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Computational Drug Repurposing: Approaches and Case Studies

Drug Patent Watch

"Reviving Old Medicines: How AI-Powered Repurposing is Revolutionizing the Pharmaceutical Industry The pharmaceutical industry is on the cusp of a revolution, driven by the power of computational drug repurposing. By leveraging cutting-edge AI and machine learning algorithms, researchers are breathing new life into old medicines, unlocking unprecedented potential for treating a wide range of diseases.

Drugs 88
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Cyberbullying in any form can be traumatizing for kids

Science Daily: Pharmacology News

New research shows that cyberbullying should be classified as an adverse childhood experience due to its strong link to trauma. Even subtle forms -- like exclusion from group chats -- can trigger PTSD-level distress. Nearly 90% of teens experienced some form of cyberbullying, accounting for 32% of the variation in trauma symptoms. Indirect harassment was most common, with more than half reporting hurtful comments, rumors or deliberate exclusion.

Research 225
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Sports, Exercise Protects Mental Health Of Growing Kids

Drugs.com

WEDNESDAY, May 14, 2025 Exercise and sports appear to help kids avoid mental health problems as they grow into young adults, a new study says.Young children who participated in sports teams and physical education classes were less likely to d.

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A bespoke CRISPR therapy suggests a blueprint for treating ‘N-of-1’ diseases

BioPharma Drive: Drug Pricing

A gene editing drug custom-made for a critically ill baby showed that, for some ultra-rare diseases, it’s possible to design and test a new CRISPR medicine in just a few months.

Disease 305
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How AI and LLMs are transforming drug discovery: part 1

Drug Target Review

The integration of artificial intelligence (AI) into scientific workflows represents both tremendous opportunity and significant challenges. I recently discussed the subject with two founders at the cutting-edge of this transformation: Andr Frana of Ergodic and Eli Pollock of Ontologic. We explored the barriers scientists face when adopting AI tools , contrasting approaches to building AI systems for specialised domains, and their visions for how these technologies will reshape scientific work.

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World's largest bat organoid platform paves the way for pandemic preparedness

Science Daily: Pharmacology News

Until now, most research has used either generalized cell samples or organoids made from just one type of tropical fruit bat, and only from a single organ. But a breakthrough has arrived: a research team has now created the world's most comprehensive bat organoid platform. These 'mini-organs' are grown from five common bat species found across Asia and Europe and represent four different organs -- airway, lungs, kidneys, and small intestine.

Research 241
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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RFK Jr. Criticized for Swimming With Grandkids in Bacteria-Filled Creek

Drugs.com

WEDNESDAY, May 14, 2025 U.S. Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. is under fire after posting photos of himself and his grandchildren swimming in a long-polluted creek. The water at Rock Creek Park in Washington, D.C., i.

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Bluebird extends deal deadline; Affimed files for insolvency

BioPharma Drive: Drug Pricing

Shareholders in Bluebird now have a choice of two offers from would-be acquirers Carlyle and SK Capital. Elsewhere, Cytokinetics shared more aficamten data and BridgeBio started a new kind of Attruby trial.

Trials 157
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The Pharmacy Benefit Management Landscape: A Music Industry Analogy

Drug Patent Watch

"The Prescription for Change: How PBM's are Ripping the Rhythm of the Pharmaceutical Industry Imagine a music industry where a single middleman controlled access to every song, dictating who could play them, when, and at what price. That's essentially the world of Pharmacy Benefit Managers (PBMs) in the pharmaceutical industry. In this exclusive article, we delve into the complex web of PBM's and their impact on the pharmacy landscape.

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Why are urban children more prone to allergies?

Science Daily: Pharmacology News

Evidence of a unique T cell may explain why urban children are more prone to allergies than rural children. Differences in the development of the gut microbiome may be an underlying cause.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Drug Effective Against Early Migraine Symptoms

Drugs.com

WEDNESDAY, May 14, 2025 -- Migraines dont just cause headaches.These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness.Whats more, those non-headache symptoms tend to crop up before a ful.

Drugs 223
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FDA delays approval decision for Biohaven rare disease drug

BioPharma Drive: Drug Pricing

Shares of the biotech fell around 15% on news the FDA is not only taking longer to review the drug, but will assemble an outside group of advisers to evaluate it as well.

FDA 245
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PIM for Azure Resources

Perficient: Drug Development

Privileged Identity Management Privileged Identity Management (PIM) is a service in Microsoft Entra ID that enables you to manage, control, and monitor access to important resources in your organization. These resources include those in Microsoft Entra ID, Azure, and other Microsoft Online Services such as Microsoft 365 or Microsoft Intune. This blog has been written to help those who want to set up just-in-time access for Azure resources and provide access to the subscription level only.

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Scientists track down mutation that makes orange cats orange

Science Daily: Pharmacology News

Many an orange cat-affiliated human will vouch for their cat's, let's say, specialness. But now scientists have confirmed that there is, in fact, something unique about ginger-hued domestic felines. In a new study, researchers have discovered the long-posited but elusive genetic mutation that makes orange cats orange -- and it appears to occur in no other mammal.

Research 229
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FDA to Review and Possibly Ban Fluoride Supplements for Kids

Drugs.com

WEDNESDAY, May 14, 2025 The U.S. Food and Drug Administration (FDA) plans to review and possibly remove prescription fluoride supplements for children from the market.The FDA announced Tuesday that it intends to conduct the review by Oct. 31, 2.

FDA 191
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Novo CEO to depart as obesity drugmaker’s challenges rise

BioPharma Drive: Drug Pricing

Lars Fruergaard Jørgensen will step down after eight years helming the Danish drugmaker, shares of which have lost more than half their value over the past 12 months.

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Leniolisib

New Drug Approvals

Leniolisib CAS 1354690-24-6 WeightAverage: 450.466 Monoisotopic: 450.199108558 Chemical FormulaC 21 H 25 F 3 N 6 O 2 CDZ-173-NX CDZ173 CDZ173-NX 1-[(3S)-3-({6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-yl}amino)pyrrolidin-1-yl]propan-1-one FDA APPROVED Joenja , 3/24/2023, To treat activated phosphoinositide 3-kinase delta syndrome Drug Trials Snapshot Leniolisib (INN [3] [4] ), sold under the brand name Joenja , is a medication used for the treatment of acti

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Eldercare robot helps people sit and stand, and catches them if they fall

Science Daily: Pharmacology News

Engineers built E-BAR, a mobile robot designed to physically support the elderly and prevent them from falling as they move around their homes. E-BAR acts as a set of robotic handlebars that follows a person from behind, allowing them to walk independently or lean on the robot's arms for support.