Sat.May 31, 2025 - Fri.Jun 06, 2025

article thumbnail

Fluoride Ban Could Create Cavities For 1 Of Every 3 U.S. Kids

Drugs.com

MONDAY, June 2, 2025 Removing fluoride from the U.S. water supply could result in more than 25 million more decayed teeth in children and teenagers within five years, a new study warns.Thats the equivalent of a decayed tooth for 1 of every 3 kid.

278
278
article thumbnail

Bristol Myers allies with BioNTech on bispecific cancer drug

BioPharma Drive: Drug Pricing

The oncology giant will pay $1.5 billion to co-develop a BioNTech drug that targets the proteins PD1 and VEGF, following Merck, and Pfizer into what’s become a competitive development race.

Drugs 293
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Brain training game offers new hope for drug-free pain management

Science Daily: Pharmacology News

A trial of an interactive game that trains people to alter their brain waves has shown promise as a treatment for nerve pain -- offering hope for a new generation of drug-free treatments.

Drugs 282
article thumbnail

Advancing Covalent Ligand and Drug Discovery beyond Cysteine

Covalent Modifiers

Gibae Kim, R. Justin Grams, and Ku-Lung Hsu Chemical Reviews 2025 DOI: 10.1021/acs.chemrev.5c00001 Targeting intractable proteins remains a key challenge in drug discovery, as these proteins often lack well-defined binding pockets or possess shallow surfaces not readily addressed by traditional drug design. Covalent chemistry has emerged as a powerful solution for accessing protein sites in difficult to ligand regions.

Drugs 130
article thumbnail

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

article thumbnail

Coffee Could Be Key To Aging Gracefully

Drugs.com

WEDNESDAY, June 4, 2025 A morning cup of coffee might do more than momentarily boost your energy and spirits.Full-test java also appears to help women age more gracefully, a new study says.Middle-aged women who regularly drank caffeinated coffee w.

277
277

More Trending

article thumbnail

Being in nature can help people with chronic back pain manage their condition

Science Daily: Pharmacology News

Researchers asked patients, some of whom had experienced lower back pain for up to 40 years, if being in nature helped them coped better with their lower back pain. They found that people able to spend time in their own gardens saw some health and wellbeing benefits. However, those able to immerse themselves in larger green spaces such as forests felt even more positive, as they were able to lose themselves in the environment and focus more on that than their pain levels.

Treatment 279
article thumbnail

Kinetic Modeling of Covalent Inhibition: Effects of Rapidly Fluctuating Intermediate States

Covalent Modifiers

Kyle Ghaby, Benot Roux bioRxiv 2025.05.28.656658; doi: [link] There is increasing interest in the discovery of small-molecule inhibitors that form covalent bonds with their targets for therapeutic applications. Nevertheless, identifying clear rational design principles remains challenging because the action of these molecules cannot be understood as common noncovalent inhibitors.

article thumbnail

Long-Lasting HIV Prevention Shot Headed Toward Approval

Drugs.com

FRIDAY, June 6, 2025 — A new injection to prevent HIV is expected to be approved by the U.S. Food and Drug Administration (FDA) later this month. If approved, the shot — lenacapavir — would be given twice a year and could be a big.

FDA 219
article thumbnail

Cullinan doubles down on bispecifics for autoimmune disease with Genrix deal

BioPharma Drive: Drug Pricing

A deal worth up to $712 million with the China-based biotech gives Cullinan T cell engagers aimed at BCMA and CD19, two targets of interest in inflammatory conditions.

Disease 236
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Tea, berries, dark chocolate and apples could lead to a longer life span, study shows

Science Daily: Pharmacology News

New research has found that those who consume a diverse range of foods rich in flavonoids, such as tea, berries, dark chocolate, and apples, could lower their risk of developing serious health conditions and have the potential to live longer.

Research 284
article thumbnail

How to Choose the Right ELN or LIMS for Early-Stage Drug Discovery

Collaborative Drug

A practical guide to selecting the right ELN or LIMS for early-stage drug discovery, focusing on usability, structure search, and scalability.

Drugs 130
article thumbnail

Pepto Bismol May Not Prevent Traveler’s Diarrhea, New Study Finds

Drugs.com

WEDNESDAY, June 4, 2025 Pepto Bismol is a go-to stomach remedy, but a new study suggests it might not help prevent diarrhea during international travel.The study, led by the U.S. Centers for Disease Control and Prevention (CDC), found that people.

article thumbnail

AstraZeneca drug could help keep a common breast cancer at bay

BioPharma Drive: Drug Pricing

Data presented at ASCO show that swapping in the oral drug camizestrant for an older therapy helped sustain the benefit of initial treatment, potentially opening a novel step in patient care.

Drugs 279
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Research shows how solar arrays can aid grasslands during drought

Science Daily: Pharmacology News

New research shows that the presence of solar panels in Colorado's grasslands may reduce water stress, improve soil moisture levels and -- particularly during dry years -- increase plant growth by about 20% or more compared to open fields.

Research 218
article thumbnail

Why radiopharmaceuticals are gaining ground in the fight against cancer

Drug Target Review

In recent years, the field of nuclear medicine has undergone a quiet revolution, particularly in its application to oncology. At the forefront of this transformation is Dr Ebrahim Delpassand, a nuclear medicine physician and the driving force behind RadioMedix (RMX), a radiopharmaceutical company focused on developing targeted diagnostics and therapies.

article thumbnail

Moderna's New Lower-Dose COVID-19 Vaccine, mNexspike, Approved by FDA

Drugs.com

TUESDAY, June 3, 2025 -- The U.S. Food and Drug Administration has approved a new lower-dose vaccine for active immunization against COVID-19 caused by severe acute respiratory syndrome coronavirus 2. The new vaccine (mNexspike [COVID-19 Vaccine.

Vaccine 255
article thumbnail

Otsuka tops Vera with kidney drug data; Regenxbio sinks on Duchenne update

BioPharma Drive: Drug Pricing

Late-stage results Otsuka presented in IgA nephropathy triggered a sell-off in Vera shares. Elsewhere, investors scrutinized Regenxbio’s Duchenne data and a brain drug study failed.

Drugs 221
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Scientists find immune molecule that supercharges plant growth

Science Daily: Pharmacology News

Scientists have discovered that a molecule known for defending animal immune systems called itaconate also plays a powerful role in plants. Researchers showed that itaconate not only exists in plant cells but actively stimulates growth, such as making corn seedlings grow taller. This surprising crossover between plant and animal biology may unlock new, natural ways to boost agriculture and even improve human health.

Research 176
article thumbnail

Synthetic Lethality in Precision Oncology: Integrating AI-Driven Discovery with Data Management Platforms

Collaborative Drug

A practical guide to selecting the right ELN or LIMS for early-stage drug discovery, focusing on usability, structure search, and scalability.

Drugs 100
article thumbnail

Diabetes Drug, Dapagliflozin, Effective For Fatty Liver Disease

Drugs.com

FRIDAY, June 6, 2025 — A repurposed diabetes drug can be an effective tool against fatty liver disease, a new clinical trial has found. Dapagliflozin helped people reduce fat levels in their liver and avoid liver scarring that comes with the.

Disease 244
article thumbnail

Daiichi Sankyo struck gold with ‘ADC’ cancer drugs. Its new CEO has to figure out what’s next.

BioPharma Drive: Drug Pricing

Enhertu, Datroway and other antibody-drug conjugates developed by Daiichi Sankyo have made the company a leader in a competitive field. Hiroyuki Okuzawa is working to keep it that way.

Drugs 202
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Millions of new solar system objects to be found and 'filmed in technicolor' -- studies predict

Science Daily: Pharmacology News

Astronomers have revealed new research showing that millions of new solar system objects are likely to be detected by a brand-new facility, which is expected to come online later this year.

Research 186
article thumbnail

The Dark Reality of Drug Patent Thickets: Innovation or Exploitation?

Drug Patent Watch

"The Patent Paradox: How Big Pharma's Web of Exclusivity is Suffocating Innovation As the world grapples with the rising costs of healthcare, a hidden culprit is quietly strangling the development of life-saving treatments: the 'patent thicket.' In a system designed to incentivize innovation, these complex webs of exclusive rights are instead fueling a culture of exploitation, where pharmaceutical giants use their patents to stifle competition and reap exorbitant profits.

article thumbnail

Troubled Kids Wait a Half-Day — Or More — In ER To Get Mental Health Care

Drugs.com

WEDNESDAY, June 4, 2025 Troubled children and teenagers are languishing hours in chaotic hospital emergency rooms, waiting for a psychiatric bed to open, a new study says.About 1 in 3 kids who go to an emergency room (ER) amid a mental health c.

Hospitals 214
article thumbnail

FDA to use new review tool on Sarepta’s gene therapy work

BioPharma Drive: Drug Pricing

The company is one of the first to receive a “platform technology designation,” which could speed the review of certain gene therapy applications it later brings to the regulator.

Therapies 201
article thumbnail

Largest-ever map of the universe reveals 10x more early galaxies than expected

Science Daily: Pharmacology News

An international team of scientists has unveiled the largest and most detailed map of the universe ever created using the James Webb Space Telescope, revealing nearly 800,000 galaxies stretching back to almost the beginning of time. The COSMOS-Web project not only challenges long-held beliefs about galaxy formation in the early universe but also unexpectedly revealed 10 times more galaxies than anticipated along with supermassive black holes Hubble couldn t see.

article thumbnail

Precision medicine’s next frontier: unlocking the power of biospecimens

Fierce BioTech

In conversation with Fierce Biotechs Chris Hayden, Austin Read, head of PPD CorEvitas Precision Medicine, Thermo Fisher Scientific, unpacks the evolving landscape of precision therapeutic and di | Austin Read of Thermo Fisher Scientific discusses how combining biospecimens with real-world data is advancing diagnostics, treatment and the future of patient care.

article thumbnail

Immunotherapy Effective Against Stomach Cancer

Drugs.com

FRIDAY, June 6, 2025 — Immunotherapy combined with chemo can give people a fighting chance against stomach and esophageal cancers, a new clinical trial says.People treated with durvalumab and chemotherapy were much more likely to go into remission.

article thumbnail

Vera drug scores in closely watched study in rare kidney disease

BioPharma Drive: Drug Pricing

Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.

Disease 184