Drug Discovery World
JULY 31, 2024
The US Food and Drug Administration (FDA) has granted Fast Track designation to Tonix Pharmaceuticals’ Tonmya (cyclobenzaprine HCl sublingual tablets) for the management of fibromyalgia. Tonmya is a non-opioid, centrally-acting analgesic drug under development for treating fibromyalgia, which is a common chronic pain condition affecting mostly women.
Science Daily: Pharmacology News
JULY 31, 2024
A new large study suggests incidence rates continued to rise in successively younger generations in 17 of the 34 cancer types, including breast, pancreatic, and gastric cancers. Mortality trends also increased in conjunction with the incidence of liver (female only), uterine corpus, gallbladder, testicular, and colorectal cancers.
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Antidote
JULY 30, 2024
In the latest installment of Talk of the Towne, we sat down with Melanie Paris, M.A., MPH, the Senior Director of Strategic Partnerships and Kidney Disease Education at the American Kidney Fund (AKF). In the discussion, we got her insights into the types of kidney disease, treatment disparities, and the importance of clinical research in the field. She also shared many valuable resources for individuals and their loved ones living with kidney disease, which are linked here.
BioPharma Drive: Drug Pricing
JULY 30, 2024
The company is letting go of 150 staffers alongside a decision to officially terminate the high-profile program, which was acquired in 2016.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
JULY 29, 2024
Collaborators SandboxAQ and NVIDIA have reported a breakthrough that allows an 80-fold speed increase in computational chemistry calculations. SandboxAQ leverages Large Quantitative Models (LQMs) and the NVIDIA CUDA-accelerated Density Matrix Renormalization Group (DMRG) algorithm. Combining the CUDA-DMRG algorithm, the NVIDIA Quantum platform, and NVIDIA accelerated computing speeds up calculations more than 80x, compared with traditional 128-core CPU computations.
Science Daily: Pharmacology News
AUGUST 2, 2024
A new study suggests that Earth's natural forces could substantially reduce Antarctica's impact on rising sea levels, but only if carbon emissions are swiftly reduced in the coming decades. By the same token, if emissions continue on the current trajectory, Antarctic ice loss could lead to more future sea level rise than previously thought.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
AUGUST 1, 2024
The drug led to a 38% reduction in the risk of death or complications from a type of heart failure, a finding that compared favorably to available treatments.
Drug Discovery World
AUGUST 1, 2024
Professor Chris Molloy , CEO of Medicines Discovery Catapult (MDC), writes about the state of the UK’s drug discovery sector, exploring economic challenges and what is needed to support the country’s rich life sciences talent. We should all be proud of and inspired by the UK life sciences sector’s rich heritage. 25% of the world’s best-selling medicines have been discovered on British soil.
Science Daily: Pharmacology News
JULY 29, 2024
SARS-CoV-2, the virus responsible for COVID-19, is widespread among wildlife species, according to new research. The virus was detected in six common backyard species, and antibodies indicating prior exposure to the virus were found in five species, with rates of exposure ranging from 40 to 60 percent depending on the species.
Drugs.com
JULY 31, 2024
WEDNESDAY, July 31, 2024 -- The number of people who trust doctors dropped steeply during the COVID-19 pandemic, a new study says.Worse, those who lost their faith in medicine are less likely to get vaccinated against COVID or the flu, researchers.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
AUGUST 2, 2024
Adaptimmune’s Tecelra is the first TCR cell therapy to reach market and, at $727,000, is also the priciest cellular medicine for cancer in the U.S.
Drug Discovery World
JULY 30, 2024
Serna Bio was founded by Rabia Khan , who is also the CEO, to unlock the transcriptome as a drug discovery target. DDW’s Megan Thomas speaks to Khan about the work her team is doing to create the first map of the druggable transcriptome, which involves understanding RNA biology to discover small molecule drugs. MT: Why is the transcriptome important for drug discovery?
Science Daily: Pharmacology News
AUGUST 1, 2024
As they are in many places around the globe, glaciers perched high in the Andes Mountains are shrinking. Now, researchers have uncovered evidence that the high-altitude tropical ice fields are likely smaller than they've been at any time since the last ice age ended 11,700 years ago.
Drugs.com
AUGUST 1, 2024
THURSDAY, Aug. 1, 2024 -- It's long been known that a daily dose of low-dose aspirin helps keep colon cancer at bay.But new research suggests that those who benefit most are folks whose lifestyles up their odds for the disease in the first.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
AUGUST 1, 2024
The biotech cited competitive pressure and “very low” expected sales in Europe for its latest guidance cut, which sent shares down by nearly 20%.
Drug Discovery World
AUGUST 2, 2024
Viking Therapeutics’ dual GLP-1/GIP receptor agonist VK2735 could become a direct competitor to Eli Lilly’s Mounjaro/Zepbound (tirzepatide), predicts data analytics company GlobalData. In February 2024, Viking Therapeutics published Phase IIa results for its VK2735 candidate, which is being investigated both as a weekly subcutaneous injection and as an oral tablet to treat obesity.
Science Daily: Pharmacology News
AUGUST 1, 2024
Researchers have developed a new model to explain the formation of giant planets such as Jupiter, which furnishes deeper insights into the processes of planet formation and could expand our understanding of planetary systems.
Drugs.com
AUGUST 1, 2024
THURSDAY, Aug. 1, 2024 -- Don't use a chemical peel to help rejuvenate your skin unless it's done under the supervision of a trained professional, the U.S. Food and Drug Administration has advised. "FDA is warning consumers not to purchase or use.
Perficient: Drug Development
AUGUST 2, 2024
Imagine a world where your business can effortlessly keep pace with technological advancements and continuously changing customer expectations. The ability to swiftly develop new technology products and applications is crucial to staying competitive. However, relying solely on in-house development capabilities is not always feasible for many organizations.
Drug Discovery World
AUGUST 1, 2024
Six teams have been accepted onto Phase II of the Cancer Tech Accelerator, the entrepreneur training programme from Capital Enterprise dedicated to supporting cutting-edge oncology technology commercialisation. Selected from the 25 teams that took part in Phase I, three of the Phase II project teams will receive a £70,000 grant to continue the development of their technology, while three more Rising Stars will benefit from four months of mentorship and training.
Science Daily: Pharmacology News
JULY 30, 2024
Researchers have found that training successive generations of generative artificial intelligence models on synthetic data gives rise to self-consuming feedback loops.
Drugs.com
AUGUST 2, 2024
FRIDAY, Aug. 2, 2024 -- Mpox cases have soared by 160% in Africa this year, as a lack of both vaccines and treatments hamper efforts to slow the spread of the virus.In a report released by the Africa Centers for Disease Control and Prevention on.
Quanticate
AUGUST 2, 2024
Real-world evidence (RWE) is changing clinical drug development, bridging the gap between controlled clinical trial environments and the complexities of everyday patient experiences. By using Real-World Data (RWD) from various sources like electronic health records (EHRs), insurance claims, and digital health tools, researchers can gather valuable insights into how drugs work in a wide range of populations.
Drug Discovery World
AUGUST 1, 2024
Researchers at Guy’s and St Thomas’, and King’s College London in the UK have found that a bacteria is toxic for head and neck cancer and could lead to better treatments for patients. Fusobacterium is usually associated with the progression of bowel cancer. However, new research published in Cancer Communications shows that in the most common type of head and neck cancer, Fusobacterium actually destroys tumour cells.
Science Daily: Pharmacology News
JULY 31, 2024
A lesser-known cannabinoid that is gaining in popularity Cannabigerol (CBG) effectively reduced anxiety in a clinical trial without the intoxication typically associated with whole plant cannabis. It may even have some memory enhancing effects, according to a new study. For the study, researchers conducted the first human clinical trial investigating the acute effects of CBG on anxiety, stress and mood.
Drugs.com
AUGUST 2, 2024
FRIDAY, Aug. 2, 2024 -- Too many women don’t know a key warning sign of endometrial cancer, the most common cancer of the female reproductive organs, a new study shows.More than one-third (37%) of women surveyed did not know that postmenopausal b.
Drug Patent Watch
JULY 30, 2024
The Power of Patent Licensing: Unlocking Innovation and Access to Medicines Patent licensing agreements have become a crucial tool in the pharmaceutical industry, allowing companies to collaborate and…
Drug Discovery World
AUGUST 1, 2024
DDW Editor Reece Armstrong speaks to Dr Steven Powell , co-founder of Glen Clova Scientific (GCS), about the company’s approach of using virus-like particles (VLPs) to treat conditions such as eczema and asthma, and what the current market looks like for this therapy area. Spun-out of the Univeristy of Dundee in 2022, Glen Clova Scientific is developing a new class of active biologic drugs for chronic inflammatory and autoimmune disorders.
Science Daily: Pharmacology News
JULY 29, 2024
July 22, 2024, was the hottest day on record, according to a NASA analysis of global daily temperature data. July 21 and 23 of this year also exceeded the previous daily record, set in July 2023. These record-breaking temperatures are part of a long-term warming trend driven by human activities, primarily the emission of greenhouse gases.
Drugs.com
JULY 30, 2024
TUESDAY, July 30, 2024 -- People taking compounded versions of Ozempic have been overdosing on the drug, the U.S. Food and Drug Administration warns.These ODs typically are due to miscommunications or miscalculations regarding dosage, the FDA.
Drug Patent Watch
JULY 31, 2024
In the high-stakes world of pharmaceutical development, effective patent portfolio management can mean the difference between blockbuster success and costly […] Source
Drug Discovery World
JULY 31, 2024
The UK Medicines and Healthcare products Regulatory Agency (MHRA) has approved a new indication for semaglutide (Wegovy) to reduce the risk of overweight and obese adults suffering from heart attacks or stroke. The GLP-1 receptor agonist is already approved for use in the treatment of obesity and for weight management, to be used alongside diet, physical activity and behavioural support.
Science Daily: Pharmacology News
JULY 30, 2024
Physicists have been exploring the theoretical possibility of spaceships driven by compressing the four-dimensional spacetime for decades. Although this so-called 'warp drive' originates from the realm of science fiction, it is based on concrete descriptions in general relativity. A new study takes things a step further -- simulating the gravitational waves such a drive might emit if it broke down.
Drugs.com
JULY 29, 2024
MONDAY, July 29, 2024 -- The U.S. Food and Drug Administration on Monday approved a new blood test that can spot colon cancer.In late May, an FDA advisory panel had voted 7-2 that the benefits outweigh the risks when using the Guardant Health's.
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