Remove Immune Response Remove RNA Remove Science
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A Visual Guide to Genome Editors

Codon

The core of the CRISPR immune response is a guide RNA (gRNA) that binds to a CRISPR-associated (Cas) protein. In wild microbes, Cas9 cuts DNA using two separate RNA molecules, called the CRISPR RNA (crRNA) and trans-activating RNA (tracrRNA). Visit our website to get a copy. Join Asimov Press.

DNA 83
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Scientists discover network of cells and genes involved in Crohn’s disease complication

Broad Institute

Cell network In 2023, Xavier’s lab used single-cell RNA sequencing to create the largest known atlas of single cells from routine biopsies of Crohn’s patients. The team thinks these cells and the collagen they produce could be responsible for making the stricture that contracts intestinal tissue. and Harry B.

Disease 111
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Engineers design more powerful RNA vaccines

Science Daily: Pharmacology News

By adding synergistic self-adjuvanting properties to Covid-19 RNA vaccines, researchers showed they could significantly boost the immune response generated in mice.

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Targeted drug treatment leads tumor cells to imitate viral infection

Broad Institute

Reporting in Science , researchers at Massachusetts General Hospital and the Broad Institute of MIT and Harvard have made a surprising discovery about these drugs. They found that mIDH1 inhibitors trick the tumor cells into thinking they are infected with a virus, causing the immune system to mount an antiviral response.

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A Molecular Biologist’s Advice For Life

LifeSciVC

One thread that has run throughout it has been my passion for science as a lens for looking at the world. In particular, I love connecting science to daily life. Pfizer’s recent campaign around “ Science Will Win ” similarly appealed to the ethos of the power of science to help humanity. Remember life’s Central Dogma.

Science 92
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Women in Stem with Dr Christine Schuberth-Wagner

Drug Target Review

Making a little tangle of DNA visible to the eye and understanding that this is the basis of complex organisms, which might be altered in disease, was the defining moment for my future path in life sciences. Communication and networking are key in any career, with science being no exception.

Science 106
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Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

DrugBank

This method was more about serendipity than science. Another promising avenue is the use of technologies like RNA interference and gene editing, which allow scientists to turn off the production of certain proteins altogether. But as molecular biology has advanced, so too has our approach to finding new drugs.