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2025 Merkin Prize in Biomedical Technology awarded to pioneers of CAR T-cell therapy

Broad Institute

The work of June, Levine, Rivire, and Sadelain laid the foundation for a whole new class of treatments. The power of a patients immune system The idea of redirecting a persons own immune system to recognize and kill cancer cells had been around for decades, but how to do it effectively and safely remained a mystery.

Therapies 119
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The Long Road to End Tuberculosis

Codon

In the 1924 novel, The Magic Mountain , Thomas Mann describes a sanatorium patient named Anton Ferge as he undergoes a painful tuberculosis (TB) treatment. Even after microbiologists discovered the bacterium that causes the illness in 1882, it wasn’t until the 1920s that researchers were able to develop a vaccine for TB.

Vaccine 115
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GSK Licenses Shigella Vaccine Candidate to Bharat Biotech

The Pharma Data

GSK Licenses Shigella Vaccine Candidate to Bharat Biotech in Push for Global Health Equity GSK today announced a significant step forward in the battle against Shigella a leading cause of diarrhoeal disease and death in children under five by licensing its Shigella vaccine candidate, altSonflex1-2-3 , to Bharat Biotech International Limited (BBIL).

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FDA takes major step to ease access to CAR-T therapy

BioPharma Drive: Drug Pricing

Alamy Dive Brief: The Food and Drug Administration is easing limitations it imposed around the complex cancer drugs known as CAR-T therapies, removing several onerous requirements as well as loosening restrictions on which facilities can provide treatment.

Therapies 178
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The Ongoing Challenges of Understanding Long COVID and Exploring Innovative Solutions

Perficient: Drug Development

In this comprehensive blog post, we will delve into the epidemiology, incidence, prevalence, costs associated with Long COVID, its impact on various stakeholders, traditional treatment approaches, and innovative solutions that leverage Artificial Intelligence (AI) to combat this ongoing challenge.

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Merck Animal Health Gets EU CVMP Positive Opinion for NUMELVI Tablets for Dogs

The Pharma Data

The European Medicines Agency’s Committee for Veterinary Medicinal Products (CVMP) has issued a positive opinion for NUMELVI™ (atinvicitinib) Tablets for Dogs — a new, first-in-class treatment designed to ease pruritus and control the clinical manifestations associated with allergic dermatitis, including atopic dermatitis in dogs.

Vaccine 40
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mRNA Therapeutics: Revolutionizing Treatment Beyond Vaccines

DrugBank

The COVID-19 pandemic brought mRNA to global prominence by developing highly effective vaccines by Moderna and Pfizer-BioNTech.   The Expanding Role of mRNA in Cancer Therapy One of the most exciting applications of mRNA therapeutics lies in cancer treatment, where leveraging the immune system to target tumors offers a novel approach.

Vaccine 97