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A Visual Guide to Genome Editors

Codon

If the same virus invades the cell a second time, the gRNA’s spacer sequence will bind to the matching viral DNA sequence, then be cut by the Cas protein. .” Despite its association with genome editing, 1 CRISPR didn’t start out as a tool for fighting genetic disease.

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Levers for Biological Progress

Codon

” Nobody really knows without trying it out in the laboratory. I’ve chosen these two because I think they are the linchpin by which we’ll be able to build broadly useful AI models for cell and molecular biology. coli divides about every 20 minutes under optimal conditions. Cutting the size of the E. minutes.

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Issue 07 is Coming on Monday

Codon

Eryney Marrogi walks us through today’s most noteworthy gene delivery vehicles — AAVs, Lentivirus, Lipid Nanoparticles, and Herpes Simplex Virus — explaining the advantages and limitations of each. Why do the 96-well plates used in molecular biology laboratories consist of 96 wells instead of 100 or 200?

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Phages could help to tackle antimicrobial resistance

Drug Target Review

Phage have been of interest to scientists as tools to understand fundamental molecular biology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. He continued: “CBASS cyclases look a lot like cGAS, so they have to be sensing something.

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Q&A With Dr. Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical for Your Gene Therapy Studies

Alta Sciences

PJ: At Altasciences, we have a range of leading-edge platforms that include ligand binding assays (LBA), NAb, TAb, flow cytometry, and ELISpot, as well as on-site molecular biology instrumentation such as Bio-Rad’s ddPCR system, the NanoDropTM One spectrophotometer, and dedicated polymerase chain reaction (PCR) chambers.

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Sosei Heptares’ COVID-19 Program Identifies Potent Broad Spectrum Anti-Viral Small Molecules for Further Development

The Pharma Data

The program is being led by Sosei Heptares and progressed in collaboration with multiple companies including Syngene International, Domainex, Fidelta, o2h Discovery, Piramal, WuXi AppTec and the MRC Laboratory of Molecular Biology.

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A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic

Broad Institute

The project is a collaboration between the Broad and the African Center of Excellence for Genomics of Infectious Diseases (ACEGID) at Redeemer’s University outside Lagos in Nigeria, where Happi is a professor of molecular biology and genomics. Rural clinics use rapid, low-cost tests to detect a few common pathogens.

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