Obstacles and innovations of macrocyclic drug development
Drug Target Review
JANUARY 16, 2025
Food and Drug Administration (FDA) approved drugs, macrocycles are used to combat a range of diseases, including cancer, viral, fungal and bacterial infections, neurodegenerative and autoimmune diseases. Journal of Medicinal Chemistry , 59(6):23122327, 2016. Journal of the American College of Cardiology , 81(16):15531564, 2023.
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