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Screening and introduction of key cell cycle microRNAs deregulated in colorectal cancer by integrated bioinformatics analysis

Chemical Biology and Drug Design

Our data imply that a precise selection of bioinformatics tools can facilitate the identification of miRNAs that impact mRNA translation at different stages of the cell cycle. The ability of these six miRNAs to impact the cell cycle in colorectal cancer may be concluded.

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A Case Study of Addgene Bioinformatics

addgene Blog

Last summer, we posted about our bioinformatics quest , which led us to Seqera Labs , a company that provides open source workflow orchestration software for data pipeline processing (Nextflow), cloud infrastructure, and secure collaboration.

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UK research partners team up to accelerate MND drug discovery

Drug Discovery World

The proposed programme uses bioinformatics approaches and experimental models to validate and de-risk a portfolio of potential MND therapeutic targets. Our plan is to use cutting-edge bioinformatics approaches and a wide range of experimental models to validate and de-risk a portfolio of potential MND therapeutic targets.”

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Optimizing OpenFold Training for Drug Discovery

Nvidia Developer: Drug Discovery

Predicting 3D protein structures from amino acid sequences has been an important long-standing question in bioinformatics. Predicting 3D protein structures from amino acid sequences has been an important long-standing question in bioinformatics. In recent years, deep.

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Clinical Microbiomics makes third acquisition in 18 months

Drug Discovery World

Clinical Microbiomics has acquired DNASense, a Danish microbiome clinical research organisation (CRO) specialised in long-read DNA and RNA sequencing technologies and bioinformatics. The acquisition adds long-read DNA and RNA sequencing technologies to Clinical Microbiomics’ multi-omics technologies for the microbiome field.

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Partners hope to “chart a new era of drug discovery”

Drug Discovery World

A new multi-year strategic partnership between M2GEN and Zephyr AI will leverage clinicogenomic data, bioinformatics, and artificial intelligence to accelerate drug discovery and expanded use cases for oncology treatments.

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ANKRD22 promotes M2 polarization in lung adenocarcinoma macrophages via the glycolytic pathway

Chemical Biology and Drug Design

The expression of ANKRD22 in LUAD and its enriched pathway were analyzed by bioinformatics analysis. Bioinformatics analysis, qRT-PCR, and western blot showed that ANKRD22 was highly expressed in LUAD, which had a positive connection with M2 marker genes. Mitochondrial membrane potential was assessed using the JC-1 probe.