Drug Discovery World

OCTOBER 4, 2024

Biotechnology company LoQus23 Therapeutics has closed its £35 million (c.$43 million) Series A financing. The financing round was led by Forbion, alongside existing investors SV Health Investors’ Dementia Discovery Fund (DDF) and Novartis Venture Fund (NVF). Forbion General Partner Rogier Rooswinkel will join LoQus23’s Board of Directors. LoQus23 was founded in 2019 by Entrepreneurs in Residence at DDF Dr David Reynolds, Dr Caroline Benn, and Dr Ruth McKernan CBE, FMedSci and seeded by SV’s Deme

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Drug Discovery Today

OCTOBER 5, 2024

Irmantas Mogila, a young scientist from Vilnius University (VU) Life Sciences Center (LSC), has joined the ranks of the most talented early-career life science researchers. He was given the prestigious international Birnstiel Award for his outstanding research results in the field of molecular biology.

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Drug Discovery World

SEPTEMBER 30, 2024

Experts from Cancer Research UK Children’s Brain Tumour Centre of Excellence in Cambridge, UK are set to share around £3.2 ($4.2) million to find and test better and less toxic ways to treat children’s brain tumours. The funding announcement comes during Childhood Cancer Awareness Month. Brain tumours are the leading cause of cancer death in children and those that do survive often face life-changing side effects as a result of their treatment.

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Nvidia Developer: Drug Discovery

OCTOBER 2, 2024

A groundbreaking drug-repurposing AI model could bring new hope to doctors and patients trying to treat diseases with limited or no existing treatment options. A groundbreaking drug-repurposing AI model could bring new hope to doctors and patients trying to treat diseases with limited or no existing treatment options. Called TxGNN, this zero-shot tool helps doctors find new uses for existing drugs for conditions that might otherwise go untreated.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Science Daily: Pharmacology News

OCTOBER 3, 2024

Comamonadacae is a family of bacteria often found growing on plastics in water. New study finds a bacterium in this family can break down the plastic for food. Researchers also identified the enzyme the bacterium use to degrade plastic. The discovery opens new possibilities for developing bacteria-based engineering solutions to help clean up difficult-to-remove plastic waste.

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Engineering Research 126

BioPharma Drive: Drug Pricing

OCTOBER 1, 2024

The company’s official launch comes five months after major investors such as Atlas Venture and Bain Capital filed a Shanghai stock exchange filing for a biotech named “Hercules CM NewCo.

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Drugs 124

Drugs.com

OCTOBER 3, 2024

THURSDAY, Oct. 3, 2024, HealthDay News -- The Southern Hemisphere's flu season is winding down, and new data shows this year's flu shot was 34.5% effective in keeping folks there who got influenza from needing hospital care. Most (68.3%) of those.

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Science Daily: Pharmacology News

OCTOBER 2, 2024

Dolphins are extremely playful, but little is known about how they -- and other marine mammals -- communicate during playtime. New research shows that bottlenose dolphins (Tursiops truncates) use the 'open mouth' facial expression -- analogous to a smile -- to communicate during social play. The dolphins almost always use the facial expression when they are in their playmate's field of view, and when playmates perceived a 'smile,' they responded in kind 33% of the time.

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BioPharma Drive: Drug Pricing

SEPTEMBER 30, 2024

The Swiss pharma is paying Regor Therapeutics $850 million to buy a pair of prospects it sees as potential successors to blockbuster medicines from Pfizer and Eli Lilly.

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Drug Discovery World

OCTOBER 3, 2024

The US Food and Drug Administration (FDA) has announced seven new clinical trial grants awarded under the Orphan Products Grants Program for clinical trials to address the unmet needs of people affected by rare diseases. In total, clinical researchers will receive approximately $17.2 million over the next four years. Newly funded projects: Palvella Therapeutics received $2.6 million to fund a Phase III study of PTX-022 (Sirolimus) for the treatment of microcystic lymphatic malformations.

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Clinical Trials

Drug Discovery Today

OCTOBER 3, 2024

Kate Shaw, founder and CEO of Innovative Trials, a global clinical trial patient recruitment and retention company, has been crowned a top ‘Woman in Pharma’ at the Pharma Industry Awards UK. She was given the award at a ceremony in Birmingham on Wednesday 18th September.

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Trials Clinical Trials 113

Drugs.com

OCTOBER 3, 2024

THURSDAY, Oct. 3, 2024 -- Americans who turn to online pharmacies to find cheaper versions of expensive prescription medications, especially opioids, may instead be buying themselves dangerous drugs that could trigger an overdose, U.S. health.

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Online Pharmacies Pharmacy Drugs 109

Science Daily: Pharmacology News

OCTOBER 2, 2024

U.S. tropical cyclones, including hurricanes, indirectly cause thousands of deaths for nearly 15 years after a storm. Researchers estimate an average U.S. tropical cyclone indirectly causes 7,000 to 11,000 excess deaths. All told, they estimate tropical storms since 1930 have contributed to between 3.6 million and 5.2 million deaths in the U.S. -- more than all deaths nationwide from motor vehicle accidents, infectious diseases, or battle deaths in wars during the same period.

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addgene Blog

OCTOBER 3, 2024

If the fall colors are inspiring you to paint your cells in equally vivid colors, you'll want to check out the 34 new preps available in the Addgene viral vector repository! This includes the first Addgene prep packaged in the AAV9-X1.1 serotype.

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Packaging 103

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drug Discovery World

OCTOBER 3, 2024

This article is sponsored by SGS. Join SGS’s Health Science team at booth 5D82 to explore their integrated drug development solutions, from analytical testing to clinical research, formulation and manufacturing development. SGS is excited to announce its participation as an exhibitor where it will present its extensive range of quality and compliance services for the health science industry.

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Drug Discovery Today

OCTOBER 2, 2024

Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer’s disease, and improve symptoms of neurodegeneration in mice.

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Drugs.com

OCTOBER 2, 2024

WEDNESDAY, Oct. 2, 2024 -- Scientists say they've discovered a protein that seems crucial to the onset of age-related macular degeneration (AMD), a common cause of blindness in older people.The research is in its very early stages, but it might.

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Research 111

Science Daily: Pharmacology News

OCTOBER 1, 2024

A research team systematically analyzed 40 empirical studies, the majority of which had found that outdoor air pollution is associated with differences in children's brains. These differences include volumes of white matter, which is associated with cognitive function, connections throughout the brain and even early markers for Alzheimer's.

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Research 111

BioPharma Drive: Drug Pricing

OCTOBER 3, 2024

Removal of Lilly’s in-demand drugs from the FDA’s shortage list ramps up pressure on the companies selling compounded versions.

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Drug Discovery World

OCTOBER 3, 2024

New data from the Phase III BouNDless trial and its ongoing open-label extension (OLE) support the long-term efficacy of ND0612 in people with Parkinson’s disease (PD) experiencing motor fluctuations. The new clinical trial data was shared at the 2024 International Congress of Parkinson’s Disease and Movement Disorders (MDS). ND0612 is being studied as a 24-hour, continuous, subcutaneous (SC) infusion of liquid levodopa/carbidopa (LD/CD).

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Drug Patent Watch

OCTOBER 1, 2024

In the complex world of intellectual property and pharmaceutical development, understanding the intricacies of patent term extension (PTE) is crucial for innovators and businesses alike. One of the most critical aspects of PTE is calculating the regulatory review period, which can significantly impact the lifespan and profitability of a patented product.

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Drugs.com

OCTOBER 1, 2024

TUESDAY, Oct. 1, 2024 -- A new law just passed in California makes it the first state to tell public schools they may no longer serve foods that contain six artificial dyes linked to health and behavior problems among children.Gov. Gavin Newsom.

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Science Daily: Pharmacology News

OCTOBER 3, 2024

The extinction of hundreds of bird species caused by humans over the last 130,000 years has led to substantial reductions in avian functional diversity -- a measure of the range of different roles and functions that birds undertake within the environment -- and resulted in the loss of approximately 3 billion years of unique evolutionary history, according to a new study.

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Broad Institute

SEPTEMBER 30, 2024

Q&A: How Terra became a backbone of public health pathogen surveillance By Allessandra DiCorato September 30, 2024 Breadcrumb Home Q&A: How Terra became a backbone of public health pathogen surveillance Bronwyn MacInnis and Daniel Park reflect on how Terra, a scalable and secure open-source platform for biomedical data management and analysis, is making genomics accessible to public health labs.

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Drug Discovery World

OCTOBER 3, 2024

Bayer AG and Asklepios BioPharmaceutical (AskBio) have announced a new strategic collaboration with Belief BioMed (BBM) to explore the potential for new gene therapies. Under the terms of the contract, the companies will combine efforts and experience in gene therapy technology to explore potential therapies in diseases that may be treatable using a liver-targeted approach.

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Drug Patent Watch

OCTOBER 1, 2024

Have you ever wondered why some medications seem to cost an arm and a leg, while others are surprisingly affordable? The answer often lies in the complex world of drug patents. Let’s dive into the fascinating realm of pharmaceutical intellectual property and explore when drug patents expire. Drug patents are a crucial aspect of the pharmaceutical industry.

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Pharmaceuticals Drugs 97

Drugs.com

OCTOBER 1, 2024

TUESDAY, Oct. 1, 2024 -- Food left in the stomach or stool left in the bowel can impede a doctor's ability to successfully perform an endoscopy or colonoscopy.Now, research finds this scenario is more likely if the patient is taking popular new.

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Science Daily: Pharmacology News

OCTOBER 3, 2024

According to a new study, colonies of ants began farming fungi when an asteroid struck Earth 66 million years ago. This asteroid impact caused a global mass extinction but also created ideal conditions for fungi to thrive. Innovative ants began cultivating the fungi, creating an evolutionary partnership that became even more tightly intertwined 27 million years ago and continues to this day.

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Quanticate

SEPTEMBER 30, 2024

In any clinical trial conduct, recording and storing data in a controlled, consistent, and reproducible manner for data retrieval and analysis is a necessity for regulatory compliance and clinical study success.

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Drug Discovery World

OCTOBER 2, 2024

The Cystic Fibrosis Antimicrobial Resistance (CF AMR) Syndicate has announced the first cohort of drug discovery projects to receive its Collaborative Discovery Programme (CDP) funding. The £3 ($3.9) million programme, funded by LifeArc, will support six early-stage novel antimicrobial projects over two years to accelerate new treatments for lung infections in people with CF.

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Drug Patent Watch

OCTOBER 1, 2024

In the world of healthcare, few topics spark as much debate and confusion as prescription drug pricing. Have you ever wondered why that little pill in your medicine cabinet costs so much? Let’s dive into the intricate world of pharmaceutical economics and uncover the factors that determine the price tags on our prescriptions.

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Drugs.com

OCTOBER 3, 2024

THURSDAY, Oct. 3, 2024 -- Japanese researchers have successfully used a transplant of human stem cells to close a hole in a key part of a monkey's retina. They say the achievement could pave the way for better treatment of small gaps that form in.

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Science Daily: Pharmacology News

OCTOBER 3, 2024

Government subsidies for business practices and processes should be approached with caution, even when they seem to be environmentally friendly, writes a group of scientists and economists. They argue that subsidies can alter market pressures, leading to unintended consequences that not only perpetuate harmful subsidies over time but also diminish the overall effectiveness of those intended to promote environmental sustainability.

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BioPharma Drive: Drug Pricing

OCTOBER 2, 2024

Biosimilar competition to aging blockbusters will erode a large chunk of the pharma giant’s top line over the next few years.

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