Science Daily: Pharmacology News

JANUARY 17, 2025

Astrophysicists have imaged a large number of exocomet belts around nearby stars, and the tiny pebbles within them. The crystal-clear images show light being emitted from these millimeter-sized pebbles within the belts that orbit 74 nearby stars of a wide variety of ages -- from those that are just emerging from birth to those in more mature systems like our own Solar System.

121

121

Drugs.com

JANUARY 17, 2025

FRIDAY, Jan. 17, 2025 -- Women past menopause can protect themselves from future fractures through infrequent, cheap IV infusions of a bone-strengthening drug. Women 50 to 60 who got two IV infusions of zoledronate (Reclast) within five years had a.

Drugs 111

Drugs 111

BioPharma Drive: Drug Pricing

JANUARY 16, 2025

Pharma dealmaking for drugs invented in China is putting pressure on U.S. biotechs to compete harder, according to investors and executives interviewed by BioPharma Dive at the J.P. Morgan Healthcare Conference.

Drugs 144

Drugs 144

Science Daily: Pharmacology News

JANUARY 16, 2025

Increasingly common since 1980, persistent multi-year droughts will continue to advance with the warming climate, warns a new study. This publicly available forty-year global quantitative inventory seeks to inform policy regarding the environmental impact of human-induced climate change. It also detected previously 'overlooked' events.

140

140

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Drugs.com

JANUARY 16, 2025

THURSDAY, Jan. 16, 2025 -- Cutting-edge targeted therapies are pushing back the line between life and death for cancer patients.However, these targeted cancer drugs frequently arent benefitting members of ethnic and racial minorities in the U.S., a.

Drugs 116

Drugs Therapies 116

Chemical Biology and Drug Design

JANUARY 20, 2025

A depression database was first constructed, and simvastatin was used as an input to predict potential targets using machine/deep learning methods. Interestingly, the P2X7/NLRP3 pathway was predicted as a potential target for simvastatin. Subsequent Animal experiment's results confirmed this predict. ABSTRACT Depression is a mental health disorder and is the fourth most prevalent disease.

Treatment 100

Treatment Disease Research 100

BioPharma Drive: Drug Pricing

JANUARY 16, 2025

AbbVie's CEO hinted his company may be less willing to invest in psychiatry after a costly setback, while Lilly explained what it got wrong forecasting GLP-1 drug demand.

Drugs 121

Drugs 121

Science Daily: Pharmacology News

JANUARY 15, 2025

The Atlantic Meridional Overturning Circulation (AMOC) has not slowed down since the mid-20th century based on the North Atlantic air-sea heat fluxes over that time. This finding contrasts with studies that have estimated a decline in the AMOC, likely because previous studies rely on sea surface temperature measurements to understand how the AMOC has changed.

138

138

Chemical Biology and Drug Design

JANUARY 20, 2025

Peptidedrug conjugates (PDCs) were produced by combining a cancer selective cell-penetrating peptide (PDIP) with camptothecin (CPT). The PDCs crossed membranes and cleavable PDCs killed melanoma cells with nanomolar potency. ABSTRACT Drug targeting strategies, such as peptidedrug conjugates (PDCs), have arisen to combat the issue of off-target toxicity that is commonly associated with chemotherapeutic small molecule drugs.

Small Molecule 100

Small Molecule Drugs International Therapies 100

PPD

JANUARY 15, 2025

As clinical trials become increasingly complex, particularly in decentralized trials and rare disease studies, sponsors experience increased challenges in site selection, forecasting and resourcing, and patient recruitment and enrollment. Advanced artificial intelligence (AI) and machine learning solutions are revolutionizing critical challenge areas.

Clinical Trials 52

Clinical Trials Trials Clinical Research Drug Development 52

Advertisement

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

BioPharma Drive: Drug Pricing

JANUARY 16, 2025

Roche's core research spans five large areas. Boris Zaïtra, who now leads corporate business development, is confident his team of dealmakers can juggle them.

Research 120

Research 120

Science Daily: Pharmacology News

JANUARY 15, 2025

New proteins not found in nature have now been designed to counteract certain highly poisonous components of snake venom. The deep learning, computational methods for developing these toxin-neutralizing proteins offer hope for creating safer, more cost-effective and more readily available therapeutics than those currently in use. Each year more than 2 million people suffer snakebites.

115

115

Drugs.com

JANUARY 20, 2025

MONDAY, Jan. 20, 2025 -- Many more Americans are turning to ketamine for kicks, a new study reports.Recreational use of the anesthetic drug among U.S. adults increased 40% between 2021 and 2022, researchers say.That follows a nearly 82% increase in.

Research 111

Research Drugs 111

addgene Blog

JANUARY 21, 2025

One of the most pivotal decisions many PhDs face when transitioning from academia to industry is whether to stay hands-on in the lab or pivot to a managerial role. For those contemplating the leap into management, the journey can be as exciting as it is challenging.

Science 52

Science 52

Advertisement

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

DS in Pharmatics

JANUARY 20, 2025

In 2023, a small pharmaceutical company faced a critical Refusal-to-File (RTF) decision from the FDA for their New Drug Application (NDA). The letter outlined numerous deficiencies, including incomplete stability data, poorly organized information, and inconsistencies in the Chemistry, Manufacturing, and Controls (CMC) section.

Pharmaceutical Companies 52

Pharmaceutical Companies FDA Pharmaceuticals Drugs 52

BioPharma Drive: Drug Pricing

JANUARY 17, 2025

Novo sells semaglutide as Ozempic and Rybelsus for diabetes and as Wegovy for obesity. In price talks, CMS will treat the different forms as a single product.

Production 109

Production Drugs 109

Science Daily: Pharmacology News

JANUARY 15, 2025

Researchers have identified nine mutations in a bird flu strain from a person in Texas. Bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.

Disease 124

Disease Research 124

Drugs.com

JANUARY 15, 2025

WEDNESDAY, Jan. 15, 2025 -- The U.S Food and Drug Administration has amended its color additive regulations to no longer allow the use of Federal Food, Drug, and Cosmetic Act (FD&C Act) Red No. 3 in food and ingested drugs.FD&C Red No. 3 is.

FDA 105

FDA Regulations Drugs 105

Advertisement

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Conversations in Drug Development Trends

JANUARY 21, 2025

Jayaprakash Kotha, MBBS, PhD, ASCP (SH), Vice President, Bioanalytical Laboratory Satish Kumar, MBB, Head of Process Improvement Continuous Innovation is a Cornerstone of Bioanalysis Approximately 80% of drugs that begin the research process fail to reach approval. What is one contributing factor that sets the 20% that do apart from the rest? Rigorous procedures to ensure that drugs are effective and safe.

Clinical Trials 52

Clinical Trials Laboratories Trials Drug Development 52

Drug Patent Watch

JANUARY 21, 2025

Breaking Down Barriers to Affordable Healthcare: The Power of Biosimilars As we navigate the complex landscape of modern healthcare, one thing is clear: the cost of prescription medications is a significant burden for many patients. The rising cost of brand-name medications has left millions of people struggling to afford the treatments they need to manage their conditions.

Biosimilars 52

Biosimilars Government Treatment Pharmaceuticals 52

BioPharma Drive: Drug Pricing

JANUARY 21, 2025

Moderna has been testing an mRNA candidate for influenza viruses like the H5 and H7 strains that are seen as pandemic threats. Others, including GSK and Pfizer, are also at work on similar shots.

Government 78

Government Vaccine Virus 78

Science Daily: Pharmacology News

JANUARY 15, 2025

A research team identified the brain's food-specific memory system and its direct role in overeating and diet-induced obesity. They found a specific population of neurons in the mouse brain that encode memories for sugar and fat, profoundly impacting food intake and body weight.

Research 121

Research 121

Drugs.com

JANUARY 17, 2025

FRIDAY, Jan. 17, 2025 -- The U.S. Centers for Disease Control and Prevention (CDC) confirmed another human H5N1 avian flu case -- otherwise known as bird flu -- in California on Thursday, bringing the nationwide total of cases to 67.California has.

Disease 105

Disease 105

Alta Sciences

JANUARY 20, 2025

The College on Problems of Drug Dependence (CPDD) iianiro Mon, 01/20/2025 - 22:06 Image CPDD_GettyImages-1047897858.

Drugs 40

Drugs 40

Drug Patent Watch

JANUARY 21, 2025

Mastering the Art of Drug Patent Portfolio Management As a pharmaceutical professional, you know how crucial it is to navigate the complex landscape of drug patents. With billions of dollars on the line, effective patent portfolio management can make all the difference between success and failure. But what does it take to excel in this field? In our latest blog post, we dive into the best practices for drug patent portfolio management.

Drugs 52

Drugs Pharmaceutical Companies Pharmaceuticals Marketing 52

BioPharma Drive: Drug Pricing

JANUARY 15, 2025

The review, which was spurred by controversy over the FDA's Aduhelm approval, recommends two main changes in agency procedures.

FDA 67

FDA 67

Drugs.com

JANUARY 17, 2025

FRIDAY, Jan. 17, 2025 -- Suffering from low back pain?Addressing your unhealthy lifestyle habits could help ease your pain better than traditional care, a new study says.Back pain sufferers who got lifestyle coaching functioned better and had.

105

105

Alta Sciences

JANUARY 20, 2025

Contract Pharma iianiro Mon, 01/20/2025 - 22:30 Image Contract_Pharma_GettyImages-624289078.

40

40

Zobio

JANUARY 16, 2025

Developing small-molecule drugs for hard-to-drug targets remains one of the toughest challenges in modern drug discovery. Targets like cytokines, transcription factors, and scaffolding proteins often lack well-defined binding pockets. Het bericht Tackling the Hard-to-Drug Frontier: The Power of Complementary Screening Modalities verscheen eerst op ZoBio - Drug Discovery Technology.

Small Molecule 40

Small Molecule Drugs 40

BioPharma Drive: Drug Pricing

JANUARY 15, 2025

While Biogen has made an opportunistic bid for partner Sage, its top executive seemed to play down the urgency for his company to go after larger deals.

67

67

Science Daily: Pharmacology News

JANUARY 15, 2025

New research has revealed that the nervous system circuitry that controls arm movement in octopuses is segmented, giving these extraordinary creatures precise control across all eight arms and hundreds of suckers to explore their environment, grasp objects, and capture prey.

Research 119

Research 119

Drugs.com

JANUARY 21, 2025

TUESDAY, Jan. 21, 2025 -- Popular GLP-1 medications for weight loss and diabetes may have unexpected benefits for reducing risks for conditions such as substance abuse, psychosis, infections and even dementia. But these drugs also come with risks.

Drugs 101

Drugs 101

Alta Sciences

JANUARY 20, 2025

17th Annual Outsourcing in Clinical Trials New England (OCT NE) iianiro Mon, 01/20/2025 - 22:43 Image OCT New_England.

Clinical Trials 40

Clinical Trials Trials 40