Drug Target Review

JUNE 30, 2025

“I was increasingly drawn to understanding the underlying biology of disease at a molecular level – the ‘why’ – and how we might harness science to create better medicines for patients,” Lepore says. “This contrasts with the historical approach of studying each protein one at a time,” says Lepore.

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Drug Target Review

JUNE 28, 2025

Amelie Croset, Senior Director of Alliances and Partnering at the therapeutics company Molecular Partners, spoke with Drug Target Review about the science behind the presentation posters, its therapeutic potential and what is next for the platform. ” From there, things moved fast. ” And what a year to make the switch. .

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Science Engineering Treatment Clinical Development 52

Science Daily: Pharmacology News

JULY 2, 2025

A cutting-edge gene therapy has significantly restored hearing in children and adults with congenital deafness, showing dramatic results just one month after a single injection. Researchers used a virus to deliver a healthy copy of the OTOF gene into the inner ear, improving auditory function across all ten participants in the study.

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Virus Therapies Research 279

Science Daily: Pharmacology News

JUNE 19, 2025

Researchers from MIT and Scripps have unveiled a promising new HIV vaccine approach that generates a powerful immune response with just one dose. By combining two immune-boosting adjuvants alum and SMNP the vaccine lingers in lymph nodes for nearly a month, encouraging the body to produce a vast array of antibodies.

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Vaccine Immune Response Disease Research 230

BioPharma Drive: Drug Pricing

JULY 8, 2025

As a drugmaking science, targeted protein degradation has matured since 2001 , when scientists Craig Crews, Ray Deshaies and others published a foundational paper on one type of protein-degrading molecule, dubbed proteolysis-targeting chimera, or PROTAC.

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Targeted Protein Degradation Small Molecule Disease Therapies 142

Drug Target Review

JULY 8, 2025

Her team sits right at the edge of innovation, where discovery science meets clinical execution. Whether developing next-gen ADCs or applying multiomics data to rethink response prediction, the OED group aims to accelerate progress and ensure promising science gets the chance to make a difference for patients, sooner rather than later.

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The Pharma Data

JUNE 18, 2025

Sebastian Arana, Head of Process Solutions within Merck’s Life Science business sector, highlighted the strategic alignment between Merck’s capabilities and Neoclease’s vision. By offering this infrastructure, Merck helps grant winners like Neoclease focus on what they do best: advancing innovative science.

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Science Therapies Disease Treatment 40

The Pharma Data

JUNE 24, 2025

By integrating USP’s trusted reference materials with Bio-Techne’s Maurice system, therapy developers now have a complete analytical solution that promotes speed, accuracy, and regulatory confidence,” said Will Geist, President of Bio-Techne’s Protein Sciences Segment. “We Senior Vice President of Global Biologics at USP.

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The Pharma Data

JUNE 18, 2025

As our science has advanced, so has the need for tighter alignment across Research and Development to ensure that we continue to scale our impact and transform the lives of patients across a growing number of diseases,” Greenstreet stated. This momentum, she noted, requires even more synergy between the research and development functions. “As

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RNA Clinical Development Science Disease 40

Drug Target Review

JULY 1, 2025

Clinical trials are expensive, slow and often limited by outdated design constraints. Placebo arms, in particular, create ethical and logistical hurdles, especially in areas like rare disease and oncology. Digital twins offer a way forward.

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Clinical Trials Trials FDA Disease 99

The Pharma Data

JUNE 25, 2025

By integrating Regulus’ expertise in microRNA science with its own deep capabilities in clinical development, regulatory affairs, and commercialization, Novartis is well-positioned to accelerate farabursen’s clinical path and potentially bring a first-in-class treatment to ADPKD patients.

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RNA Clinical Trials Disease Small Molecule 52

The Pharma Data

JUNE 25, 2025

With a robust portfolio including SPINRAZA and other innovations in neuromuscular disorders, the company remains committed to addressing unmet medical needs through advanced science and strategic collaboration.Ionis is a pioneer in antisense technology and RNA-targeted therapeutics.

Therapies 52

Therapies Trials RNA Treatment 52

Drug Target Review

JULY 11, 2025

From maths and physics to molecular biology Schnall-Levin did not begin in the life sciences. “I I took a couple of other software startup opportunities,” he adds, “but I realised I missed the genomics and science. I did physics and math as an undergraduate,” he explains. I started looking around and getting interested in biology.

Molecular Biology 69

Molecular Biology Disease Therapies Bioinformatics 69

Drug Target Review

JUNE 16, 2025

Stefan has held pivotal roles at leading life science companies including Roche and Siemens Healthineers. In addition to nearly twenty publications and patents, he also holds an Executive MBA from the University of St Gallen, Switzerland.

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Drugs Organic Chemistry Laboratories Pharmaceuticals 52

The Pharma Data

JUNE 22, 2025

However, NXT007 takes the science a step further with refined molecular engineering aimed at achieving enhanced efficacy, longer dosing intervals, and a more predictable bleeding protection profile.

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Clinical Trials Therapies Treatment Trials 40

The Pharma Data

JUNE 18, 2025

“Our continued progress in the exploration of this potential first-in-class B7-H3 antibody-drug conjugate in collaboration with Daiichi Sankyo speaks to our pursuit of novel science in the hopes of making a difference for patients in need of new options.”

Trials 40

Trials Therapies Clinical Trials Treatment 40

The Pharma Data

JULY 2, 2025

This is made possible through the company’s proprietary formulation science, including the strategic use of over 24 optimized excipient combinations that significantly reduce viscosity by up to 90% without sacrificing product integrity. WuXiHigh™ 2.0: Pushing the Boundaries With WuXiHigh™ 2.0, Source link

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Science Daily: Pharmacology News

JUNE 26, 2025

Imagine detecting a single trillionth of a gram of a molecule—like an amino acid—using just electricity and a chip smaller than your fingernail. That’s the power of a new quantum-enabled biosensor developed at EPFL.

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Disease 172

The Pharma Data

JUNE 24, 2025

A Flexible Capital Structure to Advance Revolutionary Science Under the terms of the agreement, Royalty Pharma will provide Revolution Medicines with up to $2 billion in non-dilutive and minimally dilutive capital. The funding structure consists of two primary components: a synthetic royalty deal valued at up to $1.25

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Drug Development Clinical Trials Therapies Drugs 40

Drug Target Review

JULY 7, 2025

Importantly, this roadmap complements earlier FDA initiatives supporting the use of NAMs, 8 signalling a sustained federal commitment to reducing animal use in science without compromising patient safety. To overcome these hurdles, stakeholders must invest in collaborative research, transparent data sharing and regulatory science.

Drug Research 52

Drug Research Research Animal Testing Drugs 52

Science Daily: Pharmacology News

MAY 14, 2025

The northern white rhinoceros is one of the rarest animals on Earth, with just two females left and no natural way for the species to reproduce. Now, scientists have mapped the entire genome of a northern white rhino.

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Drug Target Review

JUNE 26, 2025

In the rapidly evolving landscape of life sciences, the communication gap between laboratory scientists and data scientists remains a significant challenge. I understand what happens in the lab, which helps on the data science side because I can better appreciate the work that goes into collecting the data.

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Laboratories Science Molecular Biology Bioinformatics 52

Science Daily: Pharmacology News

MARCH 24, 2025

Maintaining a healthy diet rich in plant-based foods, with low to moderate intake of healthy animal-based foods and lower intake of ultra-processed foods, was linked to a higher likelihood of healthy aging -- defined as reaching age 70 free of major chronic diseases and with cognitive, physical, and mental health maintained, according to a new study. (..)

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Disease 304

Broad Institute

JUNE 24, 2025

To learn more, we spoke with Liu, who is the Richard Merkin Professor and director of the Merkin Institute for Transformative Technologies in Healthcare at the Broad, the Thomas Dudley Cabot Professor of the Natural Sciences at Harvard University, and a Howard Hughes Medical Institute (HHMI) investigator. Tell us about baby K.J.

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Treatment Disease DNA Clinical Trials 133

The Pharma Data

JULY 2, 2025

Through its mission “to sincerely care for each individual life and solve their unmet medical needs with a wealth of ideas and solid science,” Asahi Kasei Pharma delivers innovative pharmaceutical solutions that improve health and enhance quality of life. Source link

Trials 40

Trials Clinical Trials Pharmaceuticals Treatment 40

BioPharma Drive: Drug Pricing

JUNE 4, 2025

Doctors also wrestled with how best to use new bispecific antibodies, and expressed concern about looming cuts to science funding. Breast cancer study results impressed at this year’s meeting, but raised new questions.

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Doctors Science Drugs 176

Alta Sciences

JULY 3, 2025

Beyond the science, what’s exciting is how this technology opens doors. We enjoyed connecting with so many forward-thinking minds at CPHI and sharing how this kind of innovation is shaping the future of formulation science. Better bioavailability means better outcomes, and potentially, faster paths through development. The response?

Small Molecule 52

Small Molecule Drug Development Pharmaceuticals Science 52

The Pharma Data

JUNE 20, 2025

Beyond the clear clinical benefits demonstrated thus far, zimislecel represents a broader shift in the therapeutic landscape — one that leverages regenerative medicine, cellular engineering, and stem cell science to solve previously intractable medical challenges.

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Therapies Treatment Trials Production 40

Fierce BioTech

JUNE 30, 2025

We’re in the midst of a paradigm shift in biomarker science. | The right biomarker signature can de-risk trials, guide decisions, and survive real-world complexity. Here’s how.

Drug Development 52

Drug Development Science Trials Drugs 52

Science Daily: Pharmacology News

JULY 12, 2025

Scientists at ETH Zurich have broken new ground by generating over 400 types of nerve cells from stem cells in the lab, far surpassing previous efforts that produced only a few dozen.

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Research Regulations Therapies Disease 259

Science Daily: Pharmacology News

JANUARY 2, 2025

Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement.

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Therapies Research 292

Science Daily: Pharmacology News

FEBRUARY 10, 2025

Short snouts and a flat profile -- within a span of 100 years, humans have significantly changed the shape of the skulls of German domestic pigs. This is likely down to new breeding practices introduced at the beginning of the 20th century.

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Drug Target Review

JULY 10, 2025

Prior to Flatiron, Josh was at MIT studying computer science and working with researchers at Massachusetts General Hospital to use ML and NLP to predict patient response to cardiac resynchronisation therapy. Sometimes, it comes from solving the hardest, most overlooked problems – one molecule at a time.

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Metabolic Stability Drugs Drug Development Small Molecule 72

Science Daily: Pharmacology News

MAY 14, 2025

Apples-to-apples comparisons in the distant universe are hard to come by. Whether the subject is dwarf galaxies, supermassive black holes, or 'hot Jupiters,' astronomers can spend months or years searching for comparable objects and formations to study. And it is rarer still when those objects are side-by-side.

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Science Daily: Pharmacology News

MAY 14, 2025

Archaeopteryx is the fossil that clearly demonstrated Darwin's views. It's the oldest known fossil bird, and it helps show that all birds -- including the ones alive today -- emerged from dinosaurs. And while the first Archaeopteryx fossil was found more than 160 years ago, scientists are continuing to learn new things about this ancient animal.

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The Pharma Data

JUNE 15, 2025

The strong data presented today further exemplify their ability to translate cutting-edge science into effective, patient-centric therapeutic strategies. Genmab, together with its collaborators, is committed to improving outcomes for patients with hematologic malignancies through innovative medicines. Source link

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Therapies Treatment Trials Disease 40

Science Daily: Pharmacology News

JULY 1, 2025

Illinois engineers fused ultrafast imaging with smart algorithms to peek at living brain chemistry, turning routine MRIs into metabolic microscopes. The system distinguishes healthy regions, grades tumors, and forecasts MS flare-ups long before structural MRI can. Precision-medicine neurology just moved closer to reality.

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