Drug Discovery World

APRIL 30, 2024

Download this exclusive eBook to learn more about: The range of applications for mAbs The latest advances in protein and antibody engineering Clinical innovation in mAb development The future potential for therapeutic antibodies The post Drug discovery and the impact of mAbs appeared first on Drug Discovery World (DDW).

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Drug Discovery World

JANUARY 23, 2024

The world’s most comprehensive database for understanding microbial distribution and function in the ocean has been released, opening up new opportunities for drug discovery. The post World’s largest catalogue of ocean DNA could boost drug discovery appeared first on Drug Discovery World (DDW).

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Drug Discovery World

MAY 7, 2024

Traditional drug discovery is time-consuming and expensive, and numerous industry studies are showing a year-on-year decrease in return on investment from R&D efforts across the board. What evidence is there showing that the AI-AAM method is effective in identifying drug candidates? Secure your free place today.

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Drug Discovery World

APRIL 4, 2024

It is a next-generation, full-spectrum drug candidate that contains highly diverse microbial ecosystems and key functional groups that restore and fortify the microbiome. Diana Spencer, Senior Digital Content Editor, DDW The post Microbiome drug to be tested in IBS clinical trial appeared first on Drug Discovery World (DDW).

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Drug Discovery World

MAY 17, 2024

From a weight loss drug that prevents heart attacks and a gene therapy that restores hearing, to a vaccine that can treat viruses that don’t exist yet, our chosen news stories this week all represent potential breakthroughs in their respective fields. News round-up for 13-16 May by DDW Senior Digital Content Editor Diana Spencer.

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Drug Discovery World

MAY 14, 2024

This fantastic drug really is a gamechanger,” study lead Professor John Deanfield from University College London, UK, told The Guardian. Drug has potential benefits to society Semaglutide is a GLP-1 drug from Novo Nordisk, primarily prescribed for adults with type 2 diabetes (Ozempic) but it is also approved for weight loss as Wegovy.

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Drug Discovery World

MAY 3, 2024

The ongoing innovation and development in the drug discovery sector relies on a number of moving parts, one of which is financial support and backing. The post This week in drug discovery (29 April – 3 May) appeared first on Drug Discovery World (DDW).

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DrugBaron

FEBRUARY 16, 2024

But not everyone in drug development is playing this game. No wonder investing in drug development is so hard! The single most important skill for investing in drug development, or managing a portfolio of assets in a company, is recognizing when the “switch point” comes for each asset. And that is easier said than done.

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Drug Discovery World

APRIL 22, 2024

The discovery of two genes responsible for sensing the environment and adapting cell shape could offer potential new drug targets to stop cancer from metastasising. These genes are good candidates for drug discovery as they have a structure similar to other proteins for which drugs are already in pre-clinical development.

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Drug Discovery World

AUGUST 9, 2023

Join DDW for this exclusive free event, Are in vitro metabolism and drug-drug interaction studies critical for an investigational new drug application? In vitro ADME and drug-drug interaction (DDI) investigations are early activities in the drug development process that are critical for framing downstream decision making.

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Drug Discovery World

MAY 8, 2024

“Our study indicates that cytisinicline might be an option to fill this gap and help adult vapers to stop using e-cigarettes.” The team tested cytisinicline for vaping because the drug binds to nicotine receptors on brain cells. Study drug compliance was high; 72.7% versus 13.2%, respectively (OR, 2.0; [95% CI, 0.82-5.32]).

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Drug Discovery World

APRIL 25, 2024

This is the latest episode of the free DDW narrated podcast, titled “A look behind the scenes of the drug discovery industry” which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. You can also find The Drug Discovery World Podcast on Spotify , Google Play and Apple Podcasts.

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Drug Discovery World

APRIL 23, 2024

Traditional drug discovery is time-consuming, and expensive, and numerous industry studies are showing a year-on-year decrease in return on investment from R&D efforts across the board. What evidence is there showing that the AI-AAM method is effective in identifying drug candidates? Secure your free place today.

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Drug Discovery World

MARCH 11, 2024

The US Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) to iOnctura for its autotaxin inhibitor cambritaxestat for the treatment of pancreatic cancer. The post Orphan Drug Designation for first-in-class autotaxin cancer therapy appeared first on Drug Discovery World (DDW).

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Drug Discovery World

APRIL 2, 2024

The post Case Study: Streamline preclinical drug discovery appeared first on Drug Discovery World (DDW). Download now.

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Drug Discovery World

DECEMBER 7, 2023

A potential schizophrenia treatment, discovered at Vanderbilt University in Tennessee in the US, has been cleared by the US Food and Drug Administration for use in Phase I clinical trials. It was discovered in the labs of Craig Lindsley, Director of the Warren Center for Neuroscience Drug Discovery (WCNDD) and Director Emeritus Jeffrey Conn.

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Drug Discovery World

DECEMBER 14, 2023

With leading academic institutions and significant recent investment, Glasgow is shaping up to be an important centre for drug discovery and development in the UK. Discoveries in these areas will identify new treatments which will become the cancer drugs of the future.” DDW’s Diana Spencer explores the city’s unique ecosystem.

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Drug Discovery World

MARCH 21, 2024

This is the latest episode of the free DDW narrated podcast, titled “Flow cytometry for drug discovery research” which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: Flow cytometry technologies and cancer associated fibroblasts and Leveraging flow cytometry in drug discovery.

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Drug Discovery World

APRIL 23, 2024

Michael Wyand, PhD, Chief Executive Officer/Director, Oxeia Biopharmaceuticals explains why there’s a need for new drugs to treat traumatic brain injuries. Tremendous strides have been made with other diseases, yet there are still no FDA-approved drug therapies for TBI. It’s an exciting time in the field of concussion drug development.

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Drug Discovery World

APRIL 17, 2024

The partnership offers ELRIG’s drug discovery community access to career opportunities and provides organisations of all sizes with SRG’s talent solutions to help grow the life science sector. Sanj Kumar, CEO, ELRIG UK, said: “ELRIG and SRG have a shared ambition to advance the careers of early-stage professionals in drug discovery.

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Drug Discovery World

APRIL 23, 2024

The Birmingham Drug Discovery Hub (BDDH) has been set up to help University of Birmingham researchers to overcome the ‘valley of death’, where projects fail due to the funding gap between original research and commercial investment. The hub has attracted more than £4 ($4.9) investment from the University’s Dynamic Investment Fund (DIF).

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Drug Discovery World

APRIL 30, 2024

Traditional drug discovery is time-consuming, and expensive, and numerous industry studies are showing a year-on-year decrease in return on investment from R&D efforts across the board. What evidence is there showing that the AI-AAM method is effective in identifying drug candidates? appeared first on Drug Discovery World (DDW).

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Drug Patent Watch

APRIL 23, 2024

Drug repurposing, or identifying new therapeutic uses for existing drugs, is gaining significant momentum as a promising approach to accelerate drug development and reduce costs. This book chapter provides a… Source

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Drug Patent Watch

MAY 15, 2024

Annual Drug Patent Expirations for INOMAX Inomax is a drug marketed by Mallinckrodt Hosp and is included in one NDA. It is available from one supplier. There are fifteen patents… Source

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BioPharma Drive: Drug Pricing

MAY 16, 2024

While results indicated the drug works as intended, it didn’t have enough of an effect on a protein that’s become integral to many ALS research programs.

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BioPharma Drive: Drug Pricing

MAY 8, 2024

Intellectual property is the foundation of the drug industry’s business model. This database will track key patent expiry dates for 30 top-selling medicines.

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Broad Institute

MARCH 8, 2024

Machine Learning in Drug Discovery By Rose Circeo March 8, 2024 Breadcrumb Home Machine Learning in Drug Discovery Symposium Machine Learning in Drug Discovery The next Machine Learning in Drug Discovery Symposium will take place in Fall 2024. Check back soon for dates and registration.

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Nvidia Developer: Drug Discovery

FEBRUARY 14, 2024

The quest for new, effective treatments for diseases that remain stubbornly resistant to current therapies is at the heart of drug discovery. The quest for new, effective treatments for diseases that remain stubbornly resistant to current therapies is at the heart of drug discovery. This traditionally. This post explores how Receptor.ai

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Drugs.com

MAY 17, 2024

Justice Department on Thursday moved to reclassify marijuana as a less dangerous drug, setting the stage for a significant shift in the nation's drug policy.In FRIDAY, May 17, 2024 -- The U.S. a proposed rule sent to the federal register, officials.

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Drug Patent Watch

MAY 17, 2024

Annual Drug Patent Expirations for TYMLOS Tymlos is a drug marketed by Radius and is included in one NDA. It is available from one supplier. There are eight patents protecting… Source

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Drugs.com

MAY 17, 2024

Food and Drug Administration on Thursday approved a new drug to treat patients with an advanced form of deadly lung cancer. FRIDAY, MAY 17, 2024 -- The U.S. Importantly, tarlatamab (Imdelltra) is only for patients who have exhausted all other.

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Drug Patent Watch

APRIL 11, 2024

A paper presented at the 2nd International Conference on Systems Medicine, AI, and Drug Repurposing proposes a novel approach to overcoming the financial barriers associated with repurposing generic drugs through… Source

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Drug Patent Watch

APRIL 21, 2024

Annual Drug Patent Expirations for SOOLANTRA Soolantra is a drug marketed by Galderma Labs Lp and is included in one NDA. It is available from three suppliers. There are twelve… Source

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Drug Patent Watch

MAY 18, 2024

Annual Drug Patent Expirations for ULESFIA Ulesfia is a drug marketed by Shionogi Inc and is included in one NDA. There is one patent protecting this drug and one Paragraph… Source

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Science Daily: Pharmacology News

APRIL 24, 2024

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a new study.

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Drugs.com

APRIL 15, 2024

MONDAY, April 15, 2024 -- Americans are facing more shortages of the drugs they need for medical care than ever before, a national pharmacy database shows.The American Society of Health-System Pharmacists (ASHSP) and the University of Utah Drug.

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Cytel

MAY 7, 2024

Market exclusivity for orphan drugs traces back to the early 1980s in the United States, with the landmark Orphan Drug Act of 1983. Here we explore the evolution and impact of market exclusivity policies in the EU and US, highlighting their role in fostering innovation and accessibility in rare disease treatment.

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