BioPharma Drive: Drug Pricing

JUNE 1, 2025

Data presented at ASCO show that swapping in the oral drug camizestrant for an older therapy helped sustain the benefit of initial treatment, potentially opening a novel step in patient care.

Drugs 279

Drugs Therapies Treatment 279

Drugs.com

MAY 15, 2025

THURSDAY, May 15, 2025 — The 2023 approval of the first drug shown to slow the progression of Alzheimer’s disease came with no small amount of concern from skeptics. Lecanemab (Leqembi) modestly slows Alzheimer’s by helping the.

Drugs 275

Drugs Disease 275

Collaborative Drug

DECEMBER 6, 2024

We recently hosted an insightful webinar featuring the team from Congruence Therapeutics , who shared how they're using CDD Vault alongside their proprietary systems to manage complex drug discovery data.

Computational Chemistry 246

Computational Chemistry Drugs 246

Drugs.com

JUNE 11, 2025

WEDNESDAY, June 11, 2025 — Real-world results for blockbuster weight-loss meds like Ozempic, Wegovy and Zepbound aren’t as impressive as those promised by the drugs’ clinical trials, a new study says. People taking such GLP-1.

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Clinical Trials Drugs Trials 279

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — A repurposed diabetes drug can be an effective tool against fatty liver disease, a new clinical trial has found.Dapagliflozin helped people reduce fat levels in their liver and avoid liver scarring that comes with the c.

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Disease Clinical Trials Drugs Trials 244

BioPharma Drive: Drug Pricing

JUNE 6, 2025

Elsewhere, investors scrutinized Regenxbio’s Duchenne data and a brain drug study failed. Late-stage results Otsuka presented in IgA nephropathy triggered a sell-off in Vera shares.

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Drugs 221

BioPharma Drive: Drug Pricing

JUNE 2, 2025

Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.

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Disease Drugs Drug Research Research 184

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 An experimental drug might help people with uncontrolled high blood pressure, according to early clinical trial results.People taking lorundrostat experienced twice the decline in their systolic blood pressure than people t.

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Clinical Trials Drugs Trials 205

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — Texas has moved to fund research into ibogaine, a psychedelic drug that may help treat addiction, depression, and brain injuries. Greg Abbott signed a bill last week approving $50 million in state funds for.

Drug Research 251

Drug Research Research Drugs 251

Drugs.com

JUNE 11, 2025

Food and Drug Administration (FDA) says it plans to use artificial intelligence (AI) to help speed the approval of new drugs and medical devices. WEDNESDAY, June 11, 2025 — The U.S. That's one of several priorities federal officials detailed.

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FDA Drugs 165

Covalent Modifiers

JUNE 5, 2025

5c00001 Targeting intractable proteins remains a key challenge in drug discovery, as these proteins often lack well-defined binding pockets or possess shallow surfaces not readily addressed by traditional drug design. Justin Grams, and Ku-Lung Hsu Chemical Reviews 2025 DOI: 10.1021/acs.chemrev.5c00001

Drugs 130

Drugs 130

BioPharma Drive: Drug Pricing

MAY 12, 2025

The biotech has quickly turned a cell therapy approval into one of the more lucrative recent sales for a priority review voucher, which companies can use to fast track drug reviews.

Drugs 282

Drugs Therapies 282

BioPharma Drive: Drug Pricing

JUNE 4, 2025

Enhertu, Datroway and other antibody-drug conjugates developed by Daiichi Sankyo have made the company a leader in a competitive field. Hiroyuki Okuzawa is working to keep it that way.

Drugs 202

Drugs 202

Chemical Biology and Drug Design

JANUARY 20, 2025

ABSTRACT Drug targeting strategies, such as peptidedrug conjugates (PDCs), have arisen to combat the issue of off-target toxicity that is commonly associated with chemotherapeutic small molecule drugs. The PDCs crossed membranes and cleavable PDCs killed melanoma cells with nanomolar potency.

Small Molecule 187

Small Molecule Drugs International Therapies 187

BioPharma Drive: Drug Pricing

JUNE 11, 2025

Insmed shares rocketed on results for a pulmonary arterial hypertension drug that exceeded Wall Street expectations. Elsewhere, Recursion is laying off 20% of its workforce and Gilead halted several HIV studies.

Drugs 157

Drugs 157

Covalent Modifiers

JANUARY 9, 2025

4c00745 The term undruggable refers to proteins or other biological targets that have been historically challenging to target with conventional drugs or therapeutic strategies because of their structural, functional, or dynamic properties. Thus, investigating methods to achieve such drugging is an important challenge in medicinal chemistry.

Drugs 162

Drugs Therapies Treatment Disease 162

BioPharma Drive: Drug Pricing

MAY 5, 2025

While updated study results confirmed the drug lowers a target protein, the therapy's effect on clinical outcomes was less clear-cut.

Drugs 175

Drugs Therapies 175

BioPharma Drive: Drug Pricing

MAY 21, 2025

Founded in 2021, ReproNovo has licensed rights to two drugs from Mereo BioPharma and ObsEva that it thinks could address fertility issues in men and women.

Licensing 144

Licensing Licensing Drugs 144

BioPharma Drive: Drug Pricing

JUNE 2, 2025

Genetic research is driving progress in kidney disease drug discovery.

Disease 147

Disease Drug Development Drugs Research 147

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 -- Migraines dont just cause headaches.These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness.Whats more, those non-headache symptoms tend to crop up before a ful.

Drugs 223

Drugs 223

BioPharma Drive: Drug Pricing

MAY 14, 2025

The new acquisition from Boston Pharmaceuticals adds to a wave of dealmaking undertaken by GSK to build its liver disease franchise.

Disease 260

Disease Pharmaceuticals Drugs 260

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 — An experimental drug might help people with uncontrolled high blood pressure, according to early clinical trial results. People taking lorundrostat experienced twice the decline in their systolic blood pressure than.

Clinical Trials 173

Clinical Trials Drugs Trials 173

Collaborative Drug

JUNE 11, 2025

Compare top scientific data platforms for AI-driven drug discovery. Evaluate CDD Vault, Dotmatics, Benchling & more for chemistry and biologics workflows.

Drugs 130

Drugs 130

BioPharma Drive: Drug Pricing

OCTOBER 17, 2024

Vyalev’s clearance is the second victory for AbbVie in Parkinson’s this year, following an April readout for a drug acquired through its Cerevel buyout.

Drugs 339

Drugs 339

BioPharma Drive: Drug Pricing

SEPTEMBER 8, 2024

Study results provide much-anticipated details to Summit’s claim earlier this year that its drug “decisively beat” Merck’s dominant immunotherapy.

Drugs 339

Drugs 339

Covalent Modifiers

MAY 23, 2025

Collectively, a novel serine-targeting covalent inhibitor against hCES2A was developed, offering a promising candidate for treating drug-induced diarrhea and ulcerative colitis. In vivo tests showed that 9d significantly alleviates irinotecan-induced diarrhea and dextran sulfate sodium-induced colitis.

Drugs 147

Drugs 147

Covalent Modifiers

MAY 28, 2025

However, the inherent targeted covalent inhibitor (TCI) adverse off-target reactivity risk requires a mitigation strategy early during drug discovery. Drug induced liver injury was assessed in primary human hepatocyte spheroids. The mitigation strategy was applied to compound 35, a potent irreversible inhibitor to KRASG12C.

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Drugs Treatment Research Marketing 130

Chemical Biology and Drug Design

FEBRUARY 6, 2025

Analysis of prevalence of ring, nonring, sp 3 -, and sp 2 -hybridized oxygen in approved drugs. This work presents a comprehensive analysis of oxygen atoms in approved drugs, aiming to streamline drug design and discovery efforts. In approved drugs, majority of oxygen atoms are present within 4 from the COM of the molecule.

FDA Approval 100

FDA Approval FDA Small Molecule Pharmacokinetics 100

Science Daily: Pharmacology News

MARCH 18, 2025

A new study has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice, following from human studies.

Drugs 302

Drugs Research 302

Drugs.com

MARCH 6, 2025

THURSDAY, March 6, 2025 -- GLP-1 drugs like Ozempic can help kidney transplant patients avoid organ failure and live longer, a new study suggests.The drugs help manage patients type 2 diabetes and promote weight loss, both of which improve the c.

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Drugs 297

BioPharma Drive: Drug Pricing

JANUARY 30, 2025

Despite high demand for an option like Journavx, doctors fear the drug’s price could be a major hangup for insurers, potentially limiting patients’ ability to access it.

FDA Approval 359

FDA Approval Doctors Research FDA 359

Science Daily: Pharmacology News

JANUARY 6, 2025

Canine hookworms are becoming increasingly resistant to drugs across Australia, according to new research. Scientists have identified widespread resistance to benzimidazole-based dewormers which are commonly used to treat gastrointestinal parasites in dogs.

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Drugs Research 321

BioPharma Drive: Drug Pricing

SEPTEMBER 4, 2024

But the steady expansion of their use has slowed and, despite much trying, pharmaceutical companies have largely failed to top the drugs’ successes. Over the past 10 years, PD1-blocking medicines have transformed cancer care.

Pharmaceutical Companies 350

Pharmaceutical Companies Drugs Pharmaceuticals 350

Drugs.com

JUNE 12, 2025

Food and Drug Administration (FDA) has approved a monoclonal. THURSDAY, June 12, 2025 — A newly approved shot could soon help protect babies from respiratory syncytial virus (RSV), the top cause of hospitalization in U.S.

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Virus Hospitals FDA Drugs 289

Science Daily: Pharmacology News

MARCH 19, 2025

An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a new study.

Clinical Trials 319

Clinical Trials Drugs Trials Treatment 319

BioPharma Drive: Drug Pricing

SEPTEMBER 26, 2024

In testing, Cobenfy eased schizophrenia symptoms without some of the disruptive side effects typical of existing drugs. The results have been met with excitement, as well as caution.

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FDA Drugs 332