Drug Discovery World

MARCH 27, 2024

Their research, published in the journal Cancer Discovery , reveals the role of epigenetics in controlling how cancer cells can become dormant – and suggests a strategy to target it before the cells wake up. They also found that in people with low expression of these enzymes, their cancer had a lower risk of coming back years later.

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Drug Discovery World

SEPTEMBER 12, 2024

With an initial investment of £28 million in resources and funding, LifeArc and Cancer Research UK have launched a new initiative to develop medicines exclusively for children’s and young people’s cancers. C-Further will bring together researchers, clinicians, scientists and industry to provide support, finance and expertise.

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Drug Discovery World

JULY 5, 2024

The Division of Clinical Neuroscience at Oslo University Hospital (OUS) and the Swedish drug development company TikoMed have signed a research collaboration agreement focused on amyotrophic lateral sclerosis (ALS).

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Drug Discovery World

SEPTEMBER 16, 2024

What you will learn: Where are the breakthroughs in neuroscience research? The post Webinar on driving neuroscience drug discovery research appeared first on Drug Discovery World (DDW). How are advanced technologies proving beneficial to drug discovery and development? A Q&A session follows the webinar presentations.

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Drug Discovery World

SEPTEMBER 4, 2024

Cancer Research Horizons and AstraZeneca have signed a five-year renewal of the Functional Genomics Centre, a facility dedicated to advancing drug discovery with genome-altering technologies such as CRISPR. It helps us tap into previously unknown biology and advances our understanding of cancer resistance mechanisms.

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Drug Discovery World

SEPTEMBER 11, 2024

The Institute recently partnered with Automata to introduce high-throughput automation for their human cell model research programme.

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Drug Discovery World

JULY 11, 2024

I have always been looking to apply the research from my academic group for patient benefit, and it is incredibly exciting and satisfying to be part of the team that is driving this work towards the clinic at Curve. MT: What industry-wide drug discovery breakthrough has most impacted your research?

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Drug Discovery World

JANUARY 12, 2024

Researchers in the US have discovered that a type of immune cell in the human body known to be important for allergy and other immune responses can also attack cancer. In previous research focused on mouse cells, ILC2s had not consistently shown promise when tested for their cancer-killing abilities.

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Drug Discovery World

AUGUST 25, 2023

DDW’s Megan Thomas looks at a day in the life of Giusy Di Conza , Head of Research at iOnctura. GDC : I’m Head of Research for a young, dynamic biotech called iOnctura. We are pioneering research into new biological mechanisms for established drug targets.

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Drug Discovery World

SEPTEMBER 30, 2024

What you will learn: Where are the breakthroughs in neuroscience research? The post Last chance to register: Driving neuroscience drug discovery research appeared first on Drug Discovery World (DDW). How are advanced technologies proving beneficial to drug discovery and development? A Q&A session follows the webinar presentations.

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Drug Discovery World

APRIL 30, 2024

The centres will bring together scientists and rare disease clinical specialists from across the UK; encouraging new collaborations across different research disciplines and providing improved access to facilities and training. However, rare disease research can be fragmented. The £9.4 ($11.7) The new £9.4 ($11.7)

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Drug Discovery World

FEBRUARY 2, 2024

Head of clinical trials at the University College London (UCL) Dementia Research Centre, Dr Cath Mummery, has been announced as the Director of a new network of dementia trial sites across the country. The post UK dementia research gets £49.9 The UK government has authorised £49.9 ($63.4)

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Drug Discovery World

JUNE 6, 2024

The research, led by the Case Western Reserve University in Ohio and reported in The Guardian , also found patients were half as likely to die over 15 years compared with patients not taking a GLP-1 receptor agonist (RA).

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Drug Discovery World

SEPTEMBER 10, 2024

This state-of-the-art facility not only expands laboratory space in the heart of London and strengthens collaboration between the Crick Institute and MSD, but it also creates an environment where pioneering research can thrive, driving both economic growth and transformative advances in healthcare.”

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Drug Discovery World

JULY 21, 2023

Cancer Research Horizons has signed a collaboration agreement to license the entire Twist Biopharma Solutions Library of Libraries. The post Partnership could enhance antibody discovery for cancer research appeared first on Drug Discovery World (DDW).

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Drug Discovery World

FEBRUARY 12, 2024

The Engineering Biology Mission Award was given by UK Research and Innovation (UKRI). The research team will focus its efforts on two of these challenges: the identification of cellular production bottlenecks and cellular stresses; and the membrane environment that surround the proteins. The post UK university partnership wins £1.8m

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Drug Discovery World

SEPTEMBER 11, 2024

What you will learn: Where are the breakthroughs in neuroscience research? The post The latest advancements driving neuroscience drug discovery research appeared first on Drug Discovery World (DDW). How are advanced technologies proving beneficial to drug discovery and development? A Q&A session follows the webinar presentations.

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Drug Discovery World

AUGUST 29, 2024

The US Parkinson’s Foundation has invested nearly $3 million for 33 grants to accelerate Parkinson’s disease (PD) research. The research grants will fund scientists conducting studies across various aspects of PD to bring forward new therapies, treatments, and ultimately a cure for the disease.

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Drug Discovery World

JULY 24, 2024

Fox Foundation for Parkinson’s Research (MJFF). If our research is successful, this will represent an important new treatment option for patients.” programme and are very happy to collaborate to study patient stem cell-derived neuronal models as part of the research.” We see great potential in the CaV2.3

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Drug Discovery World

JULY 30, 2024

A new partnership between NHS Scotland, AstraZeneca and the Universities of Dundee and Glasgow hopes to accelerate research into treating chronic kidney disease. As we navigate the complex issue of chronic kidney disease, our commitment to patient-centred research remains unwavering.

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Drug Discovery World

MAY 24, 2024

Dr Paulien Baeten, postdoctoral researcher, commented: “The collaboration with etherna in this VLAIO-funded project is a great opportunity to contribute to the application of mRNA technologies in the fight against autoimmune disorders.

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Drug Discovery World

DECEMBER 28, 2023

Oxford Target Therapeutics, a company developing a promising therapy for triple negative breast cancer, is one of three UK life science companies awarded research prizes by the Rosalind Franklin Institute, based in Oxfordshire, UK. But it is instrumental for us, so the Franklin’s offer of funding and expertise will really fill a vital gap.”

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Drug Discovery World

JULY 10, 2024

In the first article, DDW Editor Reece Armstrong looks into recent research which may explain why cancers can become more aggressive. The post New podcast shining a spotlight on cancer research developments appeared first on Drug Discovery World (DDW).

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Drug Discovery World

AUGUST 15, 2024

OpenFold, a non-profit artificial intelligence (AI) research consortium focused on developing free and open-source software tools for biology and drug discovery, has added six new industry members. Joining the consortium are Astex Pharmaceuticals, Biogen, Congruence Therapeutics, Polaris Quantum Biotech, Psivant Therapeutics, and SandboxAQ.

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Drug Discovery World

AUGUST 15, 2024

Scale Biosciences (Scale Bio) has launched the ‘100 Million Cell Challenge’, which hopes to push the boundaries of single-cell genomics research, in collaboration with Ultima Genomics and NVIDIA. Researchers interested in participating can submit their project proposals from 8 August to 15 October 2024.

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Drug Discovery World

MARCH 23, 2023

iOnctura, a clinical stage biotechnology company developing cancer therapies, has published non-clinical research on roginolisib in the AACR journal Cancer Research Communications. The post Research reveals the unique biological features of roginolisib appeared first on Drug Discovery World (DDW).

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Drug Discovery World

JULY 25, 2024

UK researchers have mapped the exact variants in a gene that dramatically increase a person’s risk of developing cancer, paving the way for targeted treatment across diverse populations. The research team tested all 18,108 possible DNA changes in the BAP1 gene using ‘saturation genome editing’.

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Drug Discovery World

MAY 14, 2024

The neoadjuvant concept has become an ideal platform for both drug discovery and translational research. MT: What industry-wide drug discovery breakthrough has most impacted your research? DDW Volume 25 – Issue 2, Spring 2024 The post Meet the researcher: Dr Henrik Jespersen appeared first on Drug Discovery World (DDW).

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Drug Discovery World

JULY 15, 2024

But, as this research shows, there are several regulatory, technological, and ethical hurdles that must be navigated before this becomes a reality,” commented Ellen Berg, CSO, Alto Predict. Of the respondents that are already exploring NAMs, the most used replacements were cell cultures (64%), in silico models (47%) and organoids (36%).

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Drug Discovery World

JANUARY 26, 2024

Researchers from Tokyo University of Science (TUS) have found a simple, low-cost way to optimise the production of monoclonal antibodies (mAbs) and reduce manufacturing costs. We hope that this research will contribute to the stable production of antibody drugs and lead to lower drug prices,” concluded Dr Higashi.

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Drug Discovery World

JULY 15, 2024

From 5-10 April 2024 in San Diego, the cancer research community gathered for the annual meeting of the American Association for Cancer Research (AACR). DDW’s Megan Thomas spoke with biotech and pharma leaders to understand more about the cancer research landscape.

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Drug Discovery World

NOVEMBER 13, 2023

Researchers at the University of São Paulo (USP) in Brazil and Foresee Pharmaceuticals have tested a synthetic molecule which could increase heart function in patients with heart failure. The post Research proves synthetic molecule can mitigate heart failure appeared first on Drug Discovery World (DDW).

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Drug Discovery Today

OCTOBER 5, 2024

Irmantas Mogila, a young scientist from Vilnius University (VU) Life Sciences Center (LSC), has joined the ranks of the most talented early-career life science researchers. He was given the prestigious international Birnstiel Award for his outstanding research results in the field of molecular biology.

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Drug Discovery World

JUNE 14, 2024

Flagship Pioneering and ProFound Therapeutics have announced a collaboration to conduct foundational research to identify potential next-generation first-in-class therapies for the treatment of obesity. The collaboration is the first initiated under Flagship’s Pioneering Medicines strategic partnership with Pfizer announced in July 2023.

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Drug Discovery World

JULY 3, 2024

DDW’s Megan Thomas talks to Nicola McCarthy, Head of Research at the Milner Therapeutics Institute. NM: I’m Head of Research at the Milner Therapeutics Institute, which is part of the University of Cambridge, and I oversee both wet and dry labs of the institute. MT: Can you provide a top-line summary of your research?

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Drug Discovery World

MARCH 10, 2023

Cancer Research UK and UCB have agreed a clinical development collaboration to advance two of UCB’s investigational oncology antibody candidates through clinical trials. The post Cancer Research UK and UCB advance oncology antibody candidates appeared first on Drug Discovery World (DDW).

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Drug Discovery World

JULY 10, 2024

In the first article, DDW Editor Reece Armstrong looks into recent research which may explain why cancers can become more aggressive. The post Shining a spotlight on cancer research developments appeared first on Drug Discovery World (DDW).

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