Drug Discovery World

JUNE 6, 2024

The research, led by the Case Western Reserve University in Ohio and reported in The Guardian , also found patients were half as likely to die over 15 years compared with patients not taking a GLP-1 receptor agonist (RA).

Drug Research 195

Drug Research Research Vaccine Clinical Trials 195

Drug Discovery World

JULY 15, 2024

But, as this research shows, there are several regulatory, technological, and ethical hurdles that must be navigated before this becomes a reality,” commented Ellen Berg, CSO, Alto Predict. Of the respondents that are already exploring NAMs, the most used replacements were cell cultures (64%), in silico models (47%) and organoids (36%).

Animal Testing 173

Animal Testing Research Pharma Companies Regulations 173

Drug Discovery World

JULY 15, 2024

From 5-10 April 2024 in San Diego, the cancer research community gathered for the annual meeting of the American Association for Cancer Research (AACR). DDW’s Megan Thomas spoke with biotech and pharma leaders to understand more about the cancer research landscape.

Research 130

Research Clinical Pharmacology Therapies RNA 130

Drug Discovery World

JULY 10, 2024

In the first article, DDW Editor Reece Armstrong looks into recent research which may explain why cancers can become more aggressive. The post New podcast shining a spotlight on cancer research developments appeared first on Drug Discovery World (DDW).

Research 147

Research Clinical Trials Trials Drugs 147

Drug Discovery World

JANUARY 12, 2024

Researchers in the US have discovered that a type of immune cell in the human body known to be important for allergy and other immune responses can also attack cancer. In previous research focused on mouse cells, ILC2s had not consistently shown promise when tested for their cancer-killing abilities.

Research 289

Research Immune Response Virus Therapies 289

Drug Discovery World

FEBRUARY 2, 2024

Head of clinical trials at the University College London (UCL) Dementia Research Centre, Dr Cath Mummery, has been announced as the Director of a new network of dementia trial sites across the country. The post UK dementia research gets £49.9 The UK government has authorised £49.9 ($63.4)

Research 250

Research Clinical Trials Trials Science 250

Drug Discovery World

AUGUST 25, 2023

DDW’s Megan Thomas looks at a day in the life of Giusy Di Conza , Head of Research at iOnctura. GDC : I’m Head of Research for a young, dynamic biotech called iOnctura. We are pioneering research into new biological mechanisms for established drug targets.

Research 246

Research Drug Development Drugs Treatment 246

Drug Discovery World

JULY 10, 2024

In the first article, DDW Editor Reece Armstrong looks into recent research which may explain why cancers can become more aggressive. The post Shining a spotlight on cancer research developments appeared first on Drug Discovery World (DDW).

Research 130

Research Clinical Trials Trials Drugs 130

Drug Discovery World

JULY 3, 2024

DDW’s Megan Thomas talks to Nicola McCarthy, Head of Research at the Milner Therapeutics Institute. NM: I’m Head of Research at the Milner Therapeutics Institute, which is part of the University of Cambridge, and I oversee both wet and dry labs of the institute. MT: Can you provide a top-line summary of your research?

Research 147

Research Pharma Companies Nurses RNA 147

Drug Discovery World

MAY 24, 2024

Dr Paulien Baeten, postdoctoral researcher, commented: “The collaboration with etherna in this VLAIO-funded project is a great opportunity to contribute to the application of mRNA technologies in the fight against autoimmune disorders.

Research 130

Research Disease Production Treatment 130

Drug Discovery World

FEBRUARY 12, 2024

The Engineering Biology Mission Award was given by UK Research and Innovation (UKRI). The research team will focus its efforts on two of these challenges: the identification of cellular production bottlenecks and cellular stresses; and the membrane environment that surround the proteins. The post UK university partnership wins £1.8m

Research 263

Research Engineering Molecular Biology Protein Production 263

Drug Discovery World

JUNE 14, 2024

Flagship Pioneering and ProFound Therapeutics have announced a collaboration to conduct foundational research to identify potential next-generation first-in-class therapies for the treatment of obesity. The collaboration is the first initiated under Flagship’s Pioneering Medicines strategic partnership with Pfizer announced in July 2023.

Research 147

Research Drugs Therapies Drug Development 147

Drug Discovery World

MAY 14, 2024

The neoadjuvant concept has become an ideal platform for both drug discovery and translational research. MT: What industry-wide drug discovery breakthrough has most impacted your research? DDW Volume 25 – Issue 2, Spring 2024 The post Meet the researcher: Dr Henrik Jespersen appeared first on Drug Discovery World (DDW).

Research 147

Research Hospitals Trials Clinical Trials 147

Drug Discovery World

JULY 21, 2023

Cancer Research Horizons has signed a collaboration agreement to license the entire Twist Biopharma Solutions Library of Libraries. The post Partnership could enhance antibody discovery for cancer research appeared first on Drug Discovery World (DDW).

Research 246

Research Licensing Licensing Drugs 246

Drug Discovery World

JULY 12, 2024

The mid-year analysis indicates breast cancer could be the most researched disease area for four-years running, after topping the table last year. Following the success of therapies like Ozempic, it’s no surprise that type 2 diabetes research is being prioritised by biopharmaceutical companies.

Research 147

Research Clinical Trials Clinical Development Trials 147

Drug Discovery World

JUNE 11, 2024

Researchers have discovered a new biological pathway in inflammatory bowel disease (IBD) and related conditions that can be targeted using existing drugs. The researchers are now working with LifeArc to find ways to deliver MEK inhibitors directly to macrophages.

Disease 147

Disease Research DNA Laboratories 147

Drug Discovery World

JULY 19, 2024

Diana Spencer, Senior Digital Content Editor, DDW The post €12 million raised for extracellular protein degradation research appeared first on Drug Discovery World (DDW).

Targeted Protein Degradation 130

Targeted Protein Degradation Small Molecule Research Government 130

Drug Discovery World

DECEMBER 28, 2023

Oxford Target Therapeutics, a company developing a promising therapy for triple negative breast cancer, is one of three UK life science companies awarded research prizes by the Rosalind Franklin Institute, based in Oxfordshire, UK. But it is instrumental for us, so the Franklin’s offer of funding and expertise will really fill a vital gap.”

Research 266

Research Science Drugs Disease 266

Drug Discovery World

JUNE 26, 2024

Investigating how monocytes/macrophages contribute to the formation of these fatty plaques within arteries, the researchers have discovered that these cells can exist in different forms and there are particular macrophages which drive the development of the plaques.

Treatment 147

Treatment Research Medical Schools RNA 147

Drug Discovery World

JUNE 28, 2024

The eReport includes: A global market overview including prevalence, value and future outlook A scientific article on developing therapeutics targeting biomolecular condensates An interview with ApconiX’s Director and Co-founder, Professor Ruth Roberts, and Scientific Lead, Kimberly Rockley An exploration of the new frontiers in neuroscience The post (..)

Research 130

Research Marketing Drugs 130

Drug Discovery World

JUNE 5, 2024

The new partnership, which will involve scientists from both organisations working closely together, is part of LifeArc’s MND Translational Challenge, aimed at discovering innovative and potentially disease-modifying treatments for MND, a key component of the new UK MND Research Institute.

Bioinformatics 173

Bioinformatics Research Drugs Clinical Trials 173

Drug Discovery World

JANUARY 26, 2024

Researchers from Tokyo University of Science (TUS) have found a simple, low-cost way to optimise the production of monoclonal antibodies (mAbs) and reduce manufacturing costs. We hope that this research will contribute to the stable production of antibody drugs and lead to lower drug prices,” concluded Dr Higashi.

Research 255

Research Production Government Science 255

Drug Discovery World

JULY 19, 2024

Diana Spencer, Senior Digital Content Editor, DDW The post Dr Gonzalez-Aseguinolaza recognised for gene therapy research appeared first on Drug Discovery World (DDW).

Therapies 130

Therapies Research Clinical Trials Science 130

Drug Discovery World

MAY 13, 2024

The University of Texas MD Anderson Cancer Center has been awarded $20 million to strengthen neurodegeneration research. Driven by unparalleled proximity to patients and unmatched clinical and research expertise, Therapeutics Discovery and the BNDC can advance effective new therapies in ways not possible elsewhere.

Research 130

Research Disease Drug Development Therapies 130

Drug Discovery World

MARCH 23, 2023

iOnctura, a clinical stage biotechnology company developing cancer therapies, has published non-clinical research on roginolisib in the AACR journal Cancer Research Communications. The post Research reveals the unique biological features of roginolisib appeared first on Drug Discovery World (DDW).

Research 246

Research Clinical Research Treatment Therapies 246

Drug Discovery World

NOVEMBER 13, 2023

Researchers at the University of São Paulo (USP) in Brazil and Foresee Pharmaceuticals have tested a synthetic molecule which could increase heart function in patients with heart failure. The post Research proves synthetic molecule can mitigate heart failure appeared first on Drug Discovery World (DDW).

Research 264

Research Laboratories Pharmaceuticals Science 264

Drug Discovery World

FEBRUARY 28, 2024

Lu Rahman selects some of the year’s interesting and noteworthy advances in cancer research drug discovery and development. In the UK, according to Cancer Research UK, around 167,000 people die from cancer in the UK each year. Research into new drugs and therapeutics is on-going and is helping drive mortality rates down.

Drug Development 162

Drug Development Research Clinical Trials Drugs 162

Drug Discovery World

JUNE 17, 2024

The post New research facility for Massachusetts bio hub appeared first on Drug Discovery World (DDW).

Research 162

Research Laboratories Science International 162

Drug Discovery World

MARCH 10, 2023

Cancer Research UK and UCB have agreed a clinical development collaboration to advance two of UCB’s investigational oncology antibody candidates through clinical trials. The post Cancer Research UK and UCB advance oncology antibody candidates appeared first on Drug Discovery World (DDW).

Research 246

Research Clinical Trials Clinical Development Trials 246

Drug Discovery World

MARCH 19, 2024

ED : I’m currently a PhD researcher at the University of Glasgow. My research is focused on developing a 3D in vitro model of adipose tissue which can be used in the lab to help us better understand the complex signalling pathways of metabolic disorders and hopefully allow the discovery of better, curative treatments.

Research 147

Research Science Engineering Regulations 147

Drug Discovery World

MARCH 28, 2024

Download this exclusive eBook to learn more about: The opportunities and advances in cancer research Why liquid biopsies are important in precision medicine trials for cancer How genetic tuning will transform the reach for CAR-T therapies The latest developments in breast cancer therapy The post Breakthroughs in oncology research and drug discovery (..)

Research 130

Research Drugs Therapies Trials 130

Drug Discovery World

APRIL 29, 2024

Dr Currien MacDonald, Medical Chair Director at WCG, discusses the challenges and opportunities presented by cannabis research. Research support Support for researching cannabidiol is expanding. More importantly, cannabis research received additional governmental support for continued investigation at the end of 2022 with H.R.8454,

Research 147

Research FDA Production Drug Development 147

Drug Discovery World

JULY 5, 2023

Global Cancer Segment Market Manager at Agilent Technologies, recently sat down with DDW Editor Reece Armstrong to tell us about the developments in the ‘golden age’ of cancer research. RA: What is the current state of the cancer research industry? RA: How is Agilent supporting cancer research? Mark Garner, PhD.,

Research 246

Research Immune Response Pharmaceutical Companies Treatment 246

Drug Discovery World

MARCH 18, 2024

Landmark genetic research could allow doctors to accurately predict whether a patient is at risk of developing common diseases, decades before any symptoms would become evident. Snow Medical Research Foundation chair Tom Snow congratulated Dr Yengo, the first Snow Fellow from UQ: “Loic Yengo is a serious talent who we are proud to support.

Research 130

Research DNA Doctors Disease 130

Drug Discovery World

MAY 6, 2024

Immune B cells could be used to develop cancer targeting immunotherapies, following new research by scientists at The Institute of Cancer Research, London, the University of Oxford and University of Cambridge.

Treatment 130

Treatment Research Immune Response Virus 130

Drug Discovery World

MARCH 21, 2024

This is the latest episode of the free DDW narrated podcast, titled “Flow cytometry for drug discovery research” which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. The post Podcast: Flow cytometry for drug discovery research appeared first on Drug Discovery World (DDW).

Research 130

Research Drugs Science 130

Drug Discovery World

APRIL 11, 2024

MT: What drug discovery breakthrough has been most impactful to your research? The post Meet the Researcher: Stefano Gullà, Kling Biotherapeutics appeared first on Drug Discovery World (DDW). More importantly, we should consider the patient’s perspective to maximise safety and efficacy and minimise discomfort.

Research 147

Research Immune Response Disease Laboratories 147