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Adults with a history of low back pain went nearly twice as long without a recurrence of their back pain if they walked regularly, a world-first study has found.
One expert described trial results presented at EULAR last week as “unprecedented.” But reports of relapses in some patients drew questions about the therapies’ ultimate potential.
THURSDAY, June 20, 2024 -- Seven different kinds of microplastics have been discovered in human penises for the first time.The tiny fragments, formed when plastic products break down in the environment, were found in four of five samples of penis.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
New research shows when animals are fed a diet high in saturated fat for nine weeks, their gut bacteria change in ways that influence brain chemicals and fuel anxiety.
Peter Marks’ decision to override the objections of agency staff and broaden use of Elevidys could have a “lasting impact” on gene therapy as well as the FDA, one analyst wrote.
TUESDAY, June 18, 2024 -- Patients are less likely to fill prescriptions for the overdose-reversing drug naloxone when they have to shell out more at the pharmacy, a new study finds.Naloxone (also known by the brand name Narcan) is a critical.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
TUESDAY, June 18, 2024 -- Patients are less likely to fill prescriptions for the overdose-reversing drug naloxone when they have to shell out more at the pharmacy, a new study finds.Naloxone (also known by the brand name Narcan) is a critical.
Burlingame, CA, June 21, 2024 — Collaborative Drug Discovery (CDD), a leading provider of data management solutions for the pharmaceutical and biotechnology industries, is pleased to announce the integration of iChemLabs' industry-leading IUPAC naming technologies into CDD Vault. This integration is facilitated through the licensing of the ChemDoodle Java Application Programming Interface (API), enhancing CDD Vault’s capabilities in cheminformatics and chemical structure analysis.
THURSDAY, June 20, 2024 -- A Colombian family’s genetics are shining a spotlight on a gene that might help protect people from the ravages of Alzheimer’s disease.About 1,200 out of 6,000 family members carry a genetic variant called the “Paisa mutat.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Simple test for flu could improve diagnosis and surveillance By Allessandra DiCorato June 18, 2024 Breadcrumb Home Simple test for flu could improve diagnosis and surveillance A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus. By Allessandra DiCorato June 18, 2024 Credit: Jon Arizti-Sanz SHINE, a rapid diagnostic test developed by Pardis Sabeti's lab in 2020, uses paper strips an
The relationship between mother and child may offer clues to the mystery of why humans live longer than expected for their size -- and shed new light on what it means to be human -- according to a new study.
WEDNESDAY, June 19, 2024 -- Only a third of outpatient mental health facilities offer medications essential for treating opioid addiction, a new study finds.Standard care for treating people with opioid use disorder involves drugs like.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
In the high-stakes world of pharmaceuticals, patents play a pivotal role in safeguarding intellectual property and ensuring a return on investment for drug developers. The journey of a drug patent is a complex and intricate one, spanning from the initial filing to its eventual expiry.
Roughly one in four U.S. households have soil exceeding the new U.S. Environmental Protection Agency's lead screening levels of 200 parts per million (ppm), halved from the previous level of 400 ppm, a new study found. For households with exposure from multiple sources, the EPA lowered the guidance to 100 ppm; nearly 40% of households exceed that level, the study also found.
Interim study data suggest the Danish drugmaker can remain in the race to develop new kinds of weight loss drugs as doctors seek alternatives to the now dominant GLP-1s.
FRIDAY, June 21, 2024 -- A medication used to manage type 2 diabetes has been found effective in treating sleep apnea.The worldwide clinical trial demonstrates that tirzepatide significantly lowers breathing interruptions during sleep, a key.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
All plasmids rely on their host cell's replication machinery in order to replicate—but not always to the same extent. As described in our previous Origin of Replication post, DNA replication is initiated at the ori and may or may not be synchronized with the replication of the host cell's chromosomal DNA.
A single large population of healer cells, called regulatory T cells, is whizzing around our body -- not multiple specialist populations restricted to specific parts of the body as previously thought. These cells shut down inflammation and repair the collateral damage to cells caused after our immune system has responded to injury or illness. Tests, in mice, of a drug developed by the researchers showed that regulatory T cells can be attracted to specific body parts, boosted in number, and activ
FRIDAY, JUNE 21, 2024 -- Both the World Health Organization and Eli Lilly Co. warned Thursday that consumers should avoid fake versions of weight-loss drugs that are circulating in numerous countries.The WHO warning said that the international.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Pharmaceutical companies employ various strategies to extend the commercial life and patent protection of successful drugs. Here are some key approaches with examples: New Formulations One common strategy is to develop and patent new formulations of the existing drug compound to provide benefits like reduced dosing frequency, easier administration, improved bioavailability, or reduced side effects.
An international team of scientists has identified the oldest fossil of a sea-going reptile from the Southern Hemisphere -- a nothosaur vertebra found on New Zealand's South Island. 246 million years ago, at the beginning of the Age of Dinosaurs, New Zealand was located on the southern polar coast of a vast super-ocean called Panthalassa. 'The nothosaur found in New Zealand is over 40 million years older than the previously oldest known sauropterygian fossils from the Southern Hemisphere.
The new company, Spur Therapeutics, is getting another $50 million from Syncona to support its broadened pipeline, which targets Parkinson’s disease as well as heart conditions.
WEDNESDAY, June 20, 2024 -- Prostate medications might help reduce the risk of a specific type of dementia, a new study suggests.People were less likely to develop Lewy body dementia when taking drugs designed to treat urinary symptoms caused by an.
The article “The devil is in the divisional: an analysis of divisional patents, deadlines, declarations and suggestions for future practice” by Mieke Filler provides a comprehensive analysis of the strategic use of divisional patents in the pharmaceutical sector to delay generic and biosimilar market entry.
One in four parents describe getting their young child to bed as difficult -- and these parents are less likely to have a bedtime routine, more likely to leave on a video or TV show, and more likely to stay with their child until they're asleep.
The decision makes Elevidys available to Duchenne patients at least 4 years of age, despite mixed trial results that have led to skepticism about its effectiveness.
TUESDAY, June 18, 2024 -- Despite all the grumbling at the time, most Americans now look back upon pandemic-era policies as a good idea, a new poll shows.A majority of Americans see four key pandemic policies as “generally a good idea” in ret.
Sympathetic hyperinnervation is the leading cause of fatal ventricular arrhythmia (VA) following myocardial infarction (MI). Cardiac mast cells cause arrhythmias directly through degranulation. However, the role and mechanism of mast cell degranulation in sympathetic remodeling remain unknown. We investigated the role of oxytocin (OT) in stabilizing cardiac mast cells and improving sympathetic innervation in rats.
Researchers hope their DIY machine will help designers around the world experiment with making their own, sustainable fashion and other textiles from a range of natural ingredients -- maybe even the chitin in crab shells or agar-agar from algae.
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