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LNP formulations produce strong immune responses, data shows 

Drug Discovery World

The etherna paradigm for cLNP design is ushering in the rapid generation of novel families of delivery systems for not only vaccination but also for in vivo tolerisation for a host of autoimmune diseases.” The post LNP formulations produce strong immune responses, data shows appeared first on Drug Discovery World (DDW).

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Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

SCIENMAG: Medicine & Health

Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body. Credit: Mike […]

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T cells’ vital role in boosting immune responses

Drug Target Review

In the realm of immunology, researchers are constantly striving to unlock the intricate secrets of the human immune system. Among the many remarkable components that make up this complex defence network, T cells have emerged as powerful guardians, orchestrating an array of immune responses with great precision.

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Scientist discover protein required for an effective immune response to invading bacteria

SCIENMAG: Medicine & Health

Key Takeaways Researchers have discovered that the NLRP11 protein plays critical roles in alerting the body to a bacterial infection and initiating an immune response against it NLRP11 is present in humans and other primates but absent in mice The discovery could enable the development of mouse models that are more similar to humans for […]

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New study uses genetics to identify best sepsis treatment

Drug Discovery World

The new study, published in Cell Genomics , details the genetic basis of variability in sepsis response, and the different regulators and cell types involved in the different immune responses in each subgroup of patients. Sepsis causes an estimated 11 million deaths worldwide per year, with one death every three seconds.

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Discovery of protein’s role could improve cancer immunotherapies

Drug Discovery World

TIMP-1 is produced by dendritic cells, which are responsible for initiating immune responses and boosting the immune system’s ability to recognise and destroy cancer cells. The protein enhances antitumour immunity through self-stimulation and by activating surrounding immune cells.

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AstraZeneca’s Vaccine Produced Immune Responses in Older Patients

The Pharma Data

AstraZeneca’s COVID-19 vaccine candidate, AZD1222, elicited immune responses in older coronavirus patients similar to ones generated in younger adults, lending more promise to a vaccine that’s seen as one of the leading contenders in the race to become the first approved COVID-19 vaccine. Source link.