article thumbnail

First-in-human vaccine trial for deadly Marburg virus

Drug Discovery World

Scientists at the University of Oxford in the UK have launched a new clinical trial to test a vaccine to protect against “devastating” Marburg virus. Marburg virus is a highly virulent disease in the same family as Ebola that is fatal in up to 88% of cases and has no approved vaccines or treatments.

Virus 147
article thumbnail

Could a modified cold sore virus cure brain cancer?

Drug Discovery World

A team of scientists in the US and the UK are combining a genetically modified cold sore virus with a cancer vaccine to treat an aggressive type of brain cancer in children. The researchers will use a genetically engineered herpes simplex virus type 1 to eliminate cancer cells. million of funding for this research project.

Virus 147
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Trial to test monoclonal antibody for virus of growing concern

Drug Discovery World

EV-D68 is a virus of growing public health concern due to its association with the intermittent AFM outbreaks. To the right in the background is a colorised transmission electron micrograph of enterovirus D68 virus particles (green). 3D rendering by NIAID; micrograph, repositioned and recoloured by NIAID, courtesy of CDC.

Virus 147
article thumbnail

Novel antibodies target ‘dark side’ of influenza virus protein

Drug Discovery World

Researchers at the National Institutes of Health have identified antibodies targeting a hard-to-spot region of the influenza virus, shedding light on the relatively unexplored ‘dark side’ of the neuraminidase (NA) protein head.

Virus 147
article thumbnail

How evolution tamed a deadly virus and why we should still worry

Science Daily: Pharmacology News

Over the last century, a once-deadly mosquito-borne virus has evolved so that it no longer sickens humans. New research shows that changes in the virus's ability to target human cells paralleled the decline in illness and death.

Virus 103
article thumbnail

UK scientists prepare for Nipah virus clinical trial

Drug Discovery World

Severe Nipah virus is fatal in up to 75% of cases and survivors can be left with long-term neurological complications. Severe Nipah virus is fatal in up to 75% of cases and survivors can be left with long-term neurological complications. There are currently no approved vaccines or treatments for Nipah virus infection.

article thumbnail

Ancient Viruses Might Be Spurring Modern-Day Cancers

Drugs.com

FRIDAY, July 19, 2024 -- Cancer growth can be fueled by flecks of ancient viral DNA lodged into the genetics of modern humans, a new study says.Overall, about 8% of the human genome is made of bits of DNA left behind by viruses that infected our.

Virus 105