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Novel antibodies target ‘dark side’ of influenza virus protein

Drug Discovery World

Researchers at the National Institutes of Health have identified antibodies targeting a hard-to-spot region of the influenza virus, shedding light on the relatively unexplored ‘dark side’ of the neuraminidase (NA) protein head.

Virus 147
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UK scientists prepare for Nipah virus clinical trial

Drug Discovery World

Severe Nipah virus is fatal in up to 75% of cases and survivors can be left with long-term neurological complications. Severe Nipah virus is fatal in up to 75% of cases and survivors can be left with long-term neurological complications. There are currently no approved vaccines or treatments for Nipah virus infection.

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In-human trial begins for first potential Nipah virus vaccine

Drug Discovery World

Nipah virus is mostly found in South-East Asia that can be fatal in up to 75% of cases. This trial is a step forward in efforts to build a suite of tools to protect against this killer virus. The post In-human trial begins for first potential Nipah virus vaccine appeared first on Drug Discovery World (DDW).

Virus 130
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Next-generation antivirals could target virus membranes

Drug Discovery World

Ideally, new antivirals won’t be specific to one virus or protein, so they will be ready to treat new viruses that emerge without delay and will be able to overcome the development of resistance. “We Moreover, chikungunya virus containing higher levels of phosphatidylserine in its membrane was more susceptible to the peptoids.

Virus 130
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Swiss scientists identify a virus that kills dormant bacteria

Drug Discovery World

Researchers have found a virus that kills dormant bacteria, a discovery that could help to combat infections that can’t be treated with antibiotics. When tested in cell culture dishes, the virus was able to kill 99% of all dormant bacteria but left 1% alive. They have named their new phage Paride.

Virus 130
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Engineering viruses to kill deadly pathogens

Science Daily: Pharmacology News

Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.

Virus 115
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New antibodies target “dark side” of influenza virus protein

SCIENMAG: Medicine & Health

WHAT: Researchers at the National Institutes of Health have identified antibodies targeting a hard-to-spot region of the influenza virus, shedding light on the relatively unexplored “dark side” of the neuraminidase (NA) protein head.

Virus 83