Engineering - Drug Discovery Digest

Researchers use machine learning to engineer 'bespoke enzymes' for gene editing

Science Daily: Pharmacology News

APRIL 22, 2025

A new paper showcases the power of scalable protein engineering combined with machine learning to boost progress in the field of gene and cell therapy. Genome editing has advanced at a rapid pace with promising results for treating genetic conditions -- but there is always room for improvement.

Researchers use machine learning to engineer 'bespoke enzymes' for gene editing

Engineers make tunable, shape-changing metamaterial inspired by vintage toys

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Scientists cut harmful pollution from hydrogen engines

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Engineers design soft and flexible 'skeletons' for muscle-powered robots

Team engineers new enzyme to produce synthetic genetic material

Chimpanzees act as 'engineers', choosing materials to make tools based on structural and mechanical properties

A simple 'twist' improves the engine of clean fuel generation

Engineers conduct first in-orbit test of 'swarm' satellite autonomous navigation

Artificial reef designed by MIT engineers could protect marine life, reduce storm damage

Engineering quantum entanglement at the nanoscale

Cloud engineering could be more effective 'painkiller' for global warming than previously thought

Scientists engineer plant microbiome to protect crops against disease

Engineers harvest abundant clean energy from thin air, 24/7

Engineering a robot that can jump 10 feet high -- without legs

Engineers design tiny batteries for powering cell-sized robots

Climate engineering could slow Antarctic ice loss

Study shows engineered gut bacteria can treat hypertension

Engineers bring efficient optical neural networks into focus

Engineers develop breakthrough method for aluminum surfaces, enabling advancements in cooling, self-cleaning and anti-icing technologies

Engineers print synthetic 'metamaterials' that are both strong and stretchy

Breakthrough discovery uses engineered surfaces to shed heat

Engineers unveil breakthrough in ultra-clean biofuel technology

Engineers develop breakthrough 'robot skin'

Engineers develop a soft, printable, metal-free electrode

First mice engineered to survive COVID-19 like young, healthy humans

Harnessing vibrations: Engineered material generates electricity from unexpected source

New genetically engineered wood can store carbon and reduce emissions

Catalyst can control methane emissions in natural gas engines

International team develops novel DNA nano engine

Researchers engineer bacteria that can detect tumor DNA

A tour de force: Engineers discover new 'all-optical' nanoscale sensors of force

Researchers engineer new approach for controlling thermal emission

Engineers create an energy-storing supercapacitor from ancient materials

Engineering researchers crack the code to boost solar cell efficiency and durability

Engineers invent octopus-inspired technology that can deceive and signal

Engineers develop all-in-one solution to catch and destroy 'forever chemicals'

Watershed moment: Engineers invent high-yield atmospheric water capture device for arid regions

Engineers use AI to wrangle fusion power for the grid

Engineers design more powerful RNA vaccines

Researchers engineer colloidal quasicrystals using DNA-modified building blocks

New catalyst could dramatically cut methane pollution from millions of engines

Surgical and engineering innovations enable unprecedented control over every finger of a bionic hand

Engineers turn skin cells directly into neurons for cell therapy

A recipe for zero-emissions fuel: Soda cans, seawater, and caffeine

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