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World’s first engineered B cell therapy enters human trials

Drug Discovery World

The first patient has been dosed with an engineered B cell investigational therapy in a Phase I trial in Mucopolysaccharidosis type I (MPS I). Immusoft is advancing the world’s first engineered B cell therapy, which may have significant impact for patients with this rare disease and potentially many others.

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Genetically engineered dendritic cells enhance lung cancer therapy

Drug Discovery World

A study by researchers at the UCLA Health Jonsson Comprehensive Cancer Center in the US suggests that injecting engineered dendritic cells directly into cancerous lung tumours can help promote a stronger immune response.

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Successful clinical trial for re-engineered Covid vaccine 

Drug Discovery World

The University of Queensland’s re-engineered clamp platform has produced a vaccine that is equally safe and virus-neutralising as an approved Covid vaccine considered among the best in its class. The post Successful clinical trial for re-engineered Covid vaccine appeared first on Drug Discovery World (DDW).

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Engineers design soft and flexible 'skeletons' for muscle-powered robots

Science Daily: Pharmacology News

Engineers designed modular, spring-like devices to maximize the work of live muscle fibers so they can be harnessed to power biohybrid robots.

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A new paradigm for protein engineering 

Drug Discovery World

Adaptyv Bio, a Swiss/US technology company that develops infrastructure and tools for protein designers to engineer better proteins, has built a protein engineering foundry that it says will “pave the way” for protein designers to develop new medicines, novel enzymes and sustainable materials. And imagine each execution costs $1000.

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Desktop DNA synthesis could ‘revolutionise’ engineering biology

Drug Discovery World

The first DNA synthesised using Evonetix’s semiconductor chip technology has been delivered to the Department of Chemical Engineering and Biotechnology at the University of Cambridge. The DNA was delivered to Dr Jenny Molloy, Co-chair of the Engineering Biology Interdisciplinary Research Centre at the University of Cambridge.

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Advances continue for Evox’ exosome engineering platform 

Drug Discovery World

“The discovery and characterisation of these novel scaffolds proprietary to Evox provides a new platform for exosome-based engineering and represents a five to ten-fold improvement over previously identified exosome scaffolds,” said Dr Antonin de Fougerolles, Chief Executive Officer of Evox. The post Advances continue for Evox’ exosome engineering (..)