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Molecules of the Month – June 2023

Drug Hunter

vorasidenib – An oral first-in-class dual IDH1/IDH2 inhibitor with efficacy in Phase III trials for IDH-mutant grade 2 gliomas, discovered through structure-based drug design (SBDD) of a prior mIDH inhibitor, developed by Agios and Servier.

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Sosei teams up with Abbvie on neurological drug discovery  

Drug Discovery World

StaR technology and structure-based drug design (SBDD) platform for use throughout the project, whilst AbbVie’s will offer its expertise in neuroscience and disease. . Sosei will put forward its Heptares’?StaR

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Sosei Heptares scores $5m milestone payment from Pfizer

The Pharma Data

The collaboration has leveraged Sosei’s StaR technology and Structure-based Drug Design (SBDD) capabilities to design oral small molecules that modulate different G protein-coupled receptor (GPCR) targets across multiple disease areas.

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Sosei Heptares’ COVID-19 Program Identifies Potent Broad Spectrum Anti-Viral Small Molecules for Further Development

The Pharma Data

20, 2020 /PRNewswire/ — Sosei Group Corporation (“the Company”) (TSE: 4565) announces a progress update for its R&D program focused on the design and development of novel drugs targeting the SARS-CoV-2 coronavirus and to treat COVID-19. . TOKYO and CAMBRIDGE, England , Nov.

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Drug discovery agreement will combine AI and cryo-EM analysis

Drug Discovery World

. “We are thrilled to enter into a research collaboration with Curreio, a specialist in structural analysis of biomolecules and to combine our technology platforms to accelerate structure-based drug discovery together,” said Yann Gaston-Mathé, Co-founder and CEO of Iktos. “We

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Sosei Heptares and Captor Therapeutics Enter Strategic Technology Collaboration Focused on Targeted GPCR Degradation as Novel Approach for Drug Design

The Pharma Data

A further aim of the collaboration is to generate high resolution structural information around the GPCR-E3 ligase complex to enhance drug discovery efforts as well as provide proof of concept for targeted degradation discovery approaches with other GPCRs and other target classes.

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Sosei Heptares to Explore Structure-based Drug Discovery (SBDD) Approaches to Ion Channels through Strategic Technology Collaboration with Metrion Biosciences

The Pharma Data

. TOKYO and CAMBRIDGE, England , Feb.