April, 2024

article thumbnail

Parkinson's Disease: New theory on the disease's origins and spread

Science Daily: Pharmacology News

New hypothesis paper builds on a growing scientific consensus that Parkinson's disease route to the brain starts in either the nose or the gut and proposes that environmental toxicants are the likely source.

article thumbnail

Psychiatry drugs finally have pharma’s attention. Can they keep it?

BioPharma Drive: Drug Pricing

Recent biotech company acquisitions have put emerging schizophrenia treatments in focus. But many development hurdles still stand in the way of new medicines for the brain.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Antipsychotics May Do Great Harm to People With Dementia: Report

Drugs.com

THURSDAY, April 18, 2024 -- Antipsychotics can substantially increase dementia patients’ risk of many serious health problems, a new study warns.

article thumbnail

CDD Appoints Yasushi Hamagashira as Head of Sales and Marketing for Japan

Collaborative Drug

Tokyo, Japan, April 17, 2024 — In a significant move to bolster CDD Vault’s presence in the Japanese market, Collaborative Drug Discovery (CDD) is excited to announce the appointment of Mr. Yasushi Hamagashira as the new Head of Sales and Marketing for Japan. Bringing on board a wealth of experience and expertise, Mr. Hamagashira is set to play a pivotal role in CDD’s strategic expansion and deepening of client engagements in Japan.

article thumbnail

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

article thumbnail

New research shows 'profound' link between dietary choices and brain health

Science Daily: Pharmacology News

New research has highlighted the profound link between dietary choices and brain health.

article thumbnail

38 trillion dollars in damages each year: World economy already committed to income reduction of 19 % due to climate change

Science Daily: Pharmacology News

Even if CO2 emissions were to be drastically cut down starting today, the world economy is already committed to an income reduction of 19% until 2050 due to climate change, a new study finds. These damages are six times larger than the mitigation costs needed to limit global warming to two degrees. Based on empirical data from more than 1,600 regions worldwide over the past 40 years, scientists assessed future impacts of changing climatic conditions on economic growth and their persistence.

More Trending

article thumbnail

After being insulted, writing down your feelings on paper then getting rid of it reduces anger

Science Daily: Pharmacology News

Researchers have discovered a simple, but effective, strategy to help people reduce their feelings of anger. Disposing of a piece of paper containing your written thoughts on the cause of your anger can effectively neutralize it. This process is like a Japanese tradition called hakidashisara, in which people write their negative thoughts on a plate then destroy it.

article thumbnail

Researchers create artificial cells that act like living cells

Science Daily: Pharmacology News

Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.

article thumbnail

Cells may possess hidden communication system

Science Daily: Pharmacology News

Cells constantly navigate a dynamic environment, facing ever-changing conditions and challenges. But how do cells swiftly adapt to these environmental fluctuations? A new study is answering that question by challenging our understanding of how cells function. A team of researchers suggests that cells possess a previously unknown information processing system that allows them to make rapid decisions independent of their genes.

article thumbnail

Discovery of how limiting damage from an asthma attack could stop disease

Science Daily: Pharmacology News

Scientists have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-threatening disease.

article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Workings of working memory detailed

Science Daily: Pharmacology News

Investigators have discovered how brain cells responsible for working memory--the type required to remember a phone number long enough to dial it--coordinate intentional focus and short-term storage of information.

article thumbnail

Star Trek's Holodeck recreated using ChatGPT and video game assets

Science Daily: Pharmacology News

Star Trek's Holodeck is no longer just science fiction. Using AI, engineers have created a tool that can generate 3D environments, prompted by everyday language.

article thumbnail

Paleontologists unearth what may be the largest known marine reptile

Science Daily: Pharmacology News

The fossilized remains of a second gigantic jawbone measuring more than two meters long has been found on a beach in Somerset, UK.

article thumbnail

Physical activity reduces stress-related brain activity to lower cardiovascular disease risk

Science Daily: Pharmacology News

Over a ten-year period, biobank participants who met recommended levels of physical activity had a 23% lower risk of cardiovascular disease, and the protective effects were even more pronounced in individuals with depression.

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Revolutionary molecular device unleashes potential for targeted drug delivery and self-healing materials

Science Daily: Pharmacology News

In a new breakthrough that could revolutionise medical and material engineering, scientists have developed a first-of-its-kind molecular device that controls the release of multiple small molecules using force.

article thumbnail

With hybrid brains, these mice smell like a rat

Science Daily: Pharmacology News

Mice lacking an olfactory system have had their sense of smell restored with neurons from rats, the first time scientists have successfully integrated the sensory apparatus of one species into another.

article thumbnail

Microplastics make their way from the gut to other organs

Science Daily: Pharmacology News

Researchers have found that microplastics -- are having a significant impact on our digestive pathways, making their way from the gut and into the tissues of the kidney, liver and brain.

article thumbnail

Engineers design soft and flexible 'skeletons' for muscle-powered robots

Science Daily: Pharmacology News

Engineers designed modular, spring-like devices to maximize the work of live muscle fibers so they can be harnessed to power biohybrid robots.

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Universal brain-computer interface lets people play games with just their thoughts

Science Daily: Pharmacology News

Engineers have created a brain-computer interface that doesn't require calibration for each user, paving the way for widespread clinical applicability.

article thumbnail

What's quieter than a fish? A school of them

Science Daily: Pharmacology News

Swimming in schools makes fish surprisingly stealthy underwater, with a group able to sound like a single fish. Engineers working with a high-tech simulation of schooling mackerel offer new insight into why fish swim in schools and promise for the design and operation of much quieter submarines and autonomous undersea vehicles.

article thumbnail

More plants on the menu of ancient hunter-gatherers

Science Daily: Pharmacology News

It has long been thought that meat played an important role in the diet of hunter-gatherers before the Neolithic transition. However, due to the scarcity of well-preserved human remains from Paleolithic sites, little information exists about the dietary habits of pre-agricultural human groups. A new study challenges this notion by presenting compelling isotopic evidence of a strong preference for plants among 15,000-year-old hunter-gatherers from Morocco.

article thumbnail

Can animals count?

Science Daily: Pharmacology News

Researchers have made a groundbreaking discovery regarding number sense in animals by confirming the existence of discrete number sense in rats, offering a crucial animal model for investigating the neural basis of numerical ability and disability in humans.

article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Chatbot outperformed physicians in clinical reasoning in head-to-head study

Science Daily: Pharmacology News

ChatGPT-4, an artificial intelligence program designed to understand and generate human-like text, outperformed internal medicine residents and attending physicians at two academic medical centers at processing medical data and demonstrating clinical reasoning.

article thumbnail

Cerevel, in ‘major surprise,’ finds success in late-stage Parkinson’s study

BioPharma Drive: Drug Pricing

Analysts had low expectations for Cerevel’s drug tavapadon, which was something of an afterthought in AbbVie’s proposed buyout of the biotech.

article thumbnail

New postpartum depression drugs are here. Diagnosis, treatment hurdles still stand in the way.

BioPharma Drive: Drug Pricing

The first medicine approved for PPD, Sage’s Zulresso, never gained traction. The company is in the midst of launching its second, but long-standing challenges could slow uptake.

article thumbnail

Metsera, a well-funded obesity drug startup, sees chance to challenge Lilly, Novo

BioPharma Drive: Drug Pricing

It’s “early innings” in the obesity drug race, said Metsera CEO Clive Meanwell, whose company has acquired a portfolio of medicines it aims to test in combination.

article thumbnail

Inherited predisposition for higher muscle strength may protect against common morbidities

Science Daily: Pharmacology News

A study showed that a genetic predisposition for higher muscle strength predicts a longer lifespan and a lower risk for developing common diseases. This is a highly comprehensive international study on hereditary muscle strength and its relationship to morbidity. The genome and health data of more than 340,000 Finns was used in the research.

article thumbnail

Use of acid reflux drugs linked to higher risk of migraine

Science Daily: Pharmacology News

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a new study. The acid-reducing drugs include proton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, or H2 blockers, such as cimetidine and famotidine, and antacid supplements.

article thumbnail

Evolution's recipe book: How 'copy paste' errors cooked up the animal kingdom

Science Daily: Pharmacology News

A series of whole genome and gene duplication events that go back hundreds of millions of years have laid the foundations for tissue-specific gene expression, according to a new study. The 'copy-paste' errors allowed animals to keep one copy of their genome or genes for fundamental functions, while the second copy could be used as raw material for evolutionary innovation.

article thumbnail

Bonobos are more aggressive than previously thought

Science Daily: Pharmacology News

Chimpanzees and bonobos are often thought to reflect two different sides of human nature -- the conflict-ready chimpanzee versus the peaceful bonobo -- but a new study shows that, within their own communities, male bonobos are more frequently aggressive than male chimpanzees. For both species, more aggressive males had more mating opportunities.

article thumbnail

Biogen to invest more in launch of Alzheimer’s drug Leqembi

BioPharma Drive: Drug Pricing

Growing demand has convinced Biogen that it's worth expanding the sales force around Leqembi by 30%.

article thumbnail

Pyrite, also known as fool's gold, may contain valuable lithium, a key element for green energy

Science Daily: Pharmacology News

The technology revolution and development of new renewable energy resources is driving demand for lithium to new heights, but it is not a common mineral. Scientists say they have found lithium in an unexpected place; fool's gold, or pyrite, deposits.