Drug Discovery World

NOVEMBER 24, 2023

The pivotal proof-of-concept testing clears the way to progress the Clamp2 technology in a range of research programmes. Project leader, Associate Professor Keith Chappell, said the preliminary clinical trial results were an ‘exciting reward’ for the team’s continued dedication and the community’s widespread support for the project. “We

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Drug Discovery World

MAY 8, 2024

Fiona Maini , Senior Director Global Compliance & Strategy, at Medidata looks at the rise of artificial intelligence (AI) and machine learning (ML) within life sciences and the applications for the technology in clinical trials.

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Drug Discovery World

JULY 24, 2024

The commencement of our Phase IIa trial brings us an exciting step closer to realising that potential.” Diana Spencer, Senior Digital Content Editor, DDW The post Clinical trial will assess novel approach to cystic fibrosis appeared first on Drug Discovery World (DDW).

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Drug Discovery World

NOVEMBER 8, 2023

Deepika Khedekar , Associate Centralized Clinical Lead at IQVIA, explains how artificial intelligence could make clinical trials more accurate, accessible and standardised. Tapping into the capabilities of AI One reason AI may accelerate clinical trials is its ability to rapidly process and analyse vast amounts of data.

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Drug Discovery World

APRIL 29, 2024

Myeloma Patients Europe (MPE) has launched a new online tool to facilitate the search of clinical trials in myeloma. Solène Clavreul, Head of Medical Education and Scientific Engagement at MPE, said: “Many patients are not aware of clinical trial options.

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Drug Discovery World

MARCH 23, 2023

A series of new measures will be introduced by the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) to make it faster and easier to gain approval and run clinical trials in the UK. For example, the regulatory and ethics reviews of clinical trial applications will be integrated.

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Drugs.com

JULY 15, 2024

MONDAY, July 15, 2024 -- An experimental drug appears to help women deal with stress incontinence, clinical trial data show.The drug, for now dubbed TAS-303, reduced the frequency of leaks related to stress incontinence by about 58%, compared with.

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Drug Discovery World

MARCH 15, 2024

We look forward to a continuation of the relationship as Exonate progresses to Phase IIb clinical trials in 2024.” Megan Thomas, Multimedia Editor, DDW The post Partners enhance clinical trial design using cloud-based simulation appeared first on Drug Discovery World (DDW).

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Quanticate

JULY 22, 2024

Throughout the conduct of a clinical trial, ensuring patient safety and maintaining the integrity of the study are vital. This is where, Data Monitoring Committees (DMC) are used to support patient safety and integrity.

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Drug Discovery World

SEPTEMBER 19, 2023

The University of Oxford has revealed that researchers are currently in the advanced stages of preparing for a clinical trial of a Nipah vaccine using the ChAdOx1 vector. The post UK scientists prepare for Nipah virus clinical trial appeared first on Drug Discovery World (DDW).

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Drug Discovery World

OCTOBER 2, 2023

Sophie Winandy , Executive Director of Medical Imaging at ICON explores the benefits of AI and how it can be integrated throughout medical imaging within clinical trials. However, a judicious use of AI is warranted in clinical trials. This is in part due to the tumour’s heterogeneity in appearance and its irregular shape.

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Drug Discovery World

APRIL 26, 2024

A clinical trial of a personalised mRNA cancer vaccine for melanoma patients has been launched in the UK. The post “Game-changing” personalised cancer vaccine enters UK clinical trials appeared first on Drug Discovery World (DDW).

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Drug Discovery World

JUNE 8, 2023

Grown in vitro, these cells can provide patient specific human brain models from a large cohort of AD patients – to create a ‘clinical trial in a dish’. has paved the way for the use of cell-based assays to investigate drug safety and efficacy, including this innovative ‘clinical trial in a dish’ approach.

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Drug Discovery World

APRIL 16, 2024

Axoltis Pharma has received authorisation from ANSM, the French agency for the safety of health products, to launch the SEALS study for Amyotrophic Lateral Sclerosis (ALS). This Phase II clinical trial of drug candidate NX210c in patients with ALS is the first to target the integrity of the blood brain barrier (BBB).

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Drug Discovery World

OCTOBER 20, 2023

A new free service will offer insights in under ten days to sponsors conducting clinical trials, identifying potential ‘zombie trials’ and providing actionable recommendations for failing trials. The Health Check and Trial Rescue Service is an initiative of data software and services company Phesi.

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Antidote

APRIL 4, 2024

Before it is released onto the market, the development of any new drug or medical device must undergo rigorous testing , part of which involves clinical trials. Clinical trials are integral to making sure that any new therapy is both safe and effective for individuals, and volunteers are a vital part of the process.

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Drug Discovery World

FEBRUARY 9, 2023

Stitch Health is a London-based start-up, on a mission to improve clinical trials by measuring and surfacing each patient’s experience. million seed funding to create the definitive patient retention platform for clinical trials. MT: What other aspects of clinical trials do you feel could be improved upon?

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Drug Discovery World

MAY 17, 2023

Leveraging historical trial databases has become commonplace in assessing the feasibility of trials in therapeutic areas with a large breadth of clinical development history. EHR data also has a key role to play in designing future clinical trials.

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Drug Discovery World

SEPTEMBER 1, 2023

Accurate dose prediction for clinical trials is essential to ensure patient safety and trial success. This new whitepaper from the Jackson Laboratory discusses evidence-based selection of starting doses in first-in-human clinical trials through the utilisation of humanised mouse models.

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Antidote

MAY 30, 2024

One may choose to participate in a clinical trial for many reasons. However, deciding to enroll in a clinical trial is only one part of the process. Volunteering often has multiple benefits, from advancing medical research to gaining access to cutting-edge medical care.

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Drug Discovery World

JANUARY 16, 2024

The post Clinical trial will test novel inhaled TB vaccine appeared first on Drug Discovery World (DDW). The BCG vaccine works well against disease in childhood, but it is not good enough at protecting against disease in adulthood, which is when the majority of TB deaths occur.

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Drug Discovery World

MARCH 6, 2023

The Duke Clinical Research Institute (DCRI) and Protas, led by Oxford University clinical trialist Professor Sir Martin Landray, will collaborate to develop new approaches to large randomised clinical trials.

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Drug Discovery World

JUNE 8, 2023

The US Food and Drug Administration has published draft guidance with updated recommendations for good clinical practices (GCPs) to modernise the design and conduct of clinical trials. The updates are intended to help pave the way for more efficient clinical trials. To read this content in full, you need to login.

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Drug Discovery World

AUGUST 25, 2023

Educational campaign, Clinical Trials For All, has been launched to drive greater understanding, participation and diversity in clinical trials. Clinical research isn’t what many people think it is,” said Cinda Orr, Founder of SCORR Marketing, the company that is leading this initiative. “Low

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Drug Discovery World

OCTOBER 16, 2023

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has revealed plans to reduce the time taken to approve the lowest-risk clinical trials by more than 50%. It will reduce the time taken to get the lowest-risk clinical trials up and running without undermining patient safety.”

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Drug Discovery World

APRIL 14, 2023

Clinical trials are, undoubtedly, an essential part of the drug development process, providing us with valuable information about the safety and efficacy of new treatments and therapies. of participants 2 Covid-19 vaccination trials. In fact, these demographics which make up 13.8% of the UK population represented only 5.7%

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Drug Discovery World

JULY 17, 2023

Analysis of 13,490 clinical trials finds almost a third have been cancelled during Phase II amidst an overall decline in clinical development productivity. Data analytics company Phesi has released the results of its mid-year global analysis of all clinical trials conducted in 2023 to date.

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Drug Discovery World

JANUARY 17, 2023

In this latest episode, DDW’s Megan Thomas is in conversation with two experts when it comes to clinical trials. Walz was recently selected in the 2022 PharmaVoice 100 for the company’s innovative work in the space, and speaks about how real world data can help to boost diversity rates in clinical trials.

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Drug Discovery World

NOVEMBER 1, 2023

Enfortumab vedotin-ejfv, Astellas and Seagen The Phase III EV-302 clinical trial showed that PADCEV (enfortumab vedotin-ejfv) plus pembrolizumab improved OS and PFS vs. chemotherapy by more than 50% in patients with previously untreated locally advanced or metastatic urothelial cancer. Median PFS was 4.4 months versus 3.7

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Drug Discovery World

SEPTEMBER 4, 2023

A new whitepaper has introduced the concept of ‘cross-over’ options in cancer clinical trials, as a way to make trials more patient-centric in design. It also encourages sponsors, investigators and regulators to advance patient-centric trial designs.

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Antidote

JULY 11, 2024

When determining which clinical trial is the right fit , many factors must be considered. The site location, the number of required visits, and the length of the study are all important considerations, but before any of this, it is vital to consider the study's inclusion and exclusion criteria.

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Drug Discovery World

JULY 24, 2023

Paul O’Donohoe , Senior Director, eCOA Product and Science at Medidata, looks at the potential of decentralised clinical trials following the Covid-19 pandemic and how the industry will be affected going forward. The role that Covid-19 played in advancing decentralised clinical trials (DCTs) cannot be underestimated.

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Drug Discovery World

JULY 26, 2022

This is the latest episode of the free DDW podcast, “Now is the time for the transformation of clinical trials”. They are called “Clinical trials, the pandemic and technology” and “Pharma and the benefits of Real World Data ”. . It covers two narrated articles written for Volume 22, Issue 4 – Fall 2021 of DDW.

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Drug Discovery World

JANUARY 17, 2023

In this latest episode, DDW’s Megan Thomas is in conversation with two experts when it comes to clinical trials. Walz was recently selected in the 2022 PharmaVoice 100 for the company’s innovative work in the space, and speaks about how real world data can help to boost diversity rates in clinical trials.

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ProRelix Research

FEBRUARY 20, 2024

Crafting impactful oncology clinical trial protocols requires a strategic approach to ensure rigorous research, patient safety, and meaningful outcomes.

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