Drug Discovery World

MARCH 26, 2024

Join DDW and Revvity Signals for this free event ‘ Enhancing collaboration between sponsors and contract partners in drug discovery ’. The post Webinar: Overcome the challenges of outsourcing in drug development appeared first on Drug Discovery World (DDW). Register for free now to secure your place.

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Drug Discovery World

AUGUST 23, 2023

In vitro ADME and drug-drug interaction (DDI) investigations are early activities in the drug development process that are critical for framing downstream decision making. Participants will gain insight into the specific needs and utility for in vitro ADME and DDI investigations in the drug development process.

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Drug Discovery World

JANUARY 23, 2024

Professor Tripathi’s talk will include key examples of methods that have been implemented in the therapeutics workflow which show reduced development time, accurate and precise data generation, and more rapid data delivery to the research, manufacturing and commercial teams. See the full programme and register your interest in this event.

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Drug Discovery World

AUGUST 16, 2023

In vitro ADME and drug-drug interaction (DDI) investigations are early activities in the drug development process that are critical for framing downstream decision making. Participants will gain insight into the specific needs and utility for in vitro ADME and DDI investigations in the drug development process.

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Drug Discovery World

FEBRUARY 28, 2024

A Phase I clinical trial, sponsored and managed by Cancer Research UK’s Centre for Drug Development, tested whether a type of antibody called IgE could be used to treat cancer. The drug, MOv18 IgE (an anti-folate receptor alpha IgE antibody), was developed by researchers at King’s College London.

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Drug Discovery World

JUNE 2, 2023

Download this exclusive eBook to learn more about: The latest advancements in artificial intelligence How machine learning is being used across cancer research Why AI is critical to solving challenges in drug discovery How AI can improve drug development for rare diseases Access the eBook here.

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Drug Discovery World

JUNE 22, 2023

This is the latest episode of the free DDW narrated podcast, “Challenges and tactics for transformative drug development” It covers two articles written for Volume 23, Issue 2 – Spring 2022 of DDW. They are called “ Balancing speed and quality in CLD for faster drug development ”, and “ Sitting down with BridgeBio Pharma ”.

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Drug Discovery World

APRIL 20, 2023

Dr Paula Moran, Dr Kiri Granger, Dr J Mark Treherne , and Dr Jenny Barnett explore the effects of long Covid-19 symptoms and what the opportunities are for drug developers working to treat post-Covid-19 cognitive impairment. These may provide an opportunity for treatment for post-Covid-19 cognitive impairment.

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Drug Discovery World

APRIL 14, 2023

Dr Schon is applying his broad expertise from lead discovery to manufacture in order to progress differentiated, safe and developable bi-specific therapeutic ADC candidates to clinical development. He says it is no secret that the costs of antibody drug development are steadily increasing to ‘eye-watering heights’ per approved drug 1.

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Drug Discovery World

JULY 25, 2023

Justin Hay , Senior Director, Amy Cheung Senior Director of Integrated Drug Development, and Patrick Loebs Director, at Certara, examine recent changes in paediatric guidelines and how they affect drug development projects. The guidance mentions PBPK four times regarding renal function and DDIs. Updated 2022 Apr 28].

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Drug Discovery World

FEBRUARY 13, 2023

The event will cover aspects affecting growth of the CGT market, including how manufacturing technologies are enabling drug development, what these therapies mean for the healthcare market, and the opportunities for developers. autologous therapies/solid tumours/ indications outside of oncology?)     Register for free here.

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Drug Discovery World

JUNE 27, 2023

Sponsors evaluating the therapeutic potential of these drugs should consider their unique characteristics when designing clinical studies,” said Tiffany Farchione, Director of the Division of Psychiatry in the FDA’s Center for Drug Evaluation and Research. “By

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Drug Discovery World

AUGUST 9, 2023

In vitro ADME and drug-drug interaction (DDI) investigations are early activities in the drug development process that are critical for framing downstream decision making. Participants will gain insight into the specific needs and utility for in vitro ADME and DDI investigations in the drug development process.

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Drug Discovery World

JUNE 22, 2023

This is the latest episode of the free DDW narrated podcast, “Challenges and tactics for transformative drug development” It covers two articles written for Volume 23, Issue 2 – Spring 2022 of DDW. They are called “ Balancing speed and quality in CLD for faster drug development ”, and “ Sitting down with BridgeBio Pharma ”.

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Drug Discovery World

NOVEMBER 29, 2023

The simulator could also be used by pharmaceutical companies to rapidly test multiple drug therapies and patient scenarios, increasing the speed and cost of drug development. The post Mathematical model can speed up Alzheimer’s drug development appeared first on Drug Discovery World (DDW).

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Drug Discovery World

JUNE 30, 2023

Research tools, safety testing and regenerative medicines – these endless stem cell applications are powering precision, speed, and new modalities in drug development. Stem cells for use in drug discovery Stem cells are fast becoming an invaluable tool in the drug discovery process.

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Drug Discovery World

OCTOBER 31, 2023

Professor Andy Whiting and Dr Tony Lockett discuss how specific levels of a protein could be used to advance drug development in neurodegenerative diseases. The post Could NfL accelerate drug development for neurodegenerative diseases? appeared first on Drug Discovery World (DDW).

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Drug Discovery World

FEBRUARY 28, 2023

Dr Asma Patel , Vice President of Integrated Services for Early Development at Quotient Sciences, reflects on the biggest barriers to rare disease drug development and how companies can overcome these. The post What is the biggest barrier to rare disease drug development?

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Drug Discovery World

SEPTEMBER 1, 2022

The anti-evolocumab antibodies are approved for in vitro research purposes and for commercial in vitro testing services to support preclinical and clinical drug development. The post New anti-evolocumab antibodies could aid drug development appeared first on Drug Discovery World (DDW).

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Drug Discovery World

OCTOBER 10, 2023

The grant is intended to support the entire trajectory of drug development – from the proof-of-concept studies through to the IND-enabling studies required for a clinical trial and the Phase I/II clinical trial for both diseases.

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Drug Discovery World

SEPTEMBER 8, 2022

New norms set during the COVID-19 pandemic have only fueled the industry’s expectations of accelerated drug development,” said James Matcham, Executive Strategic Consultant, Cytel, Australia. . But APAC-based developers’ efforts to adopt trial-optimising innovation have been stifled by the services currently on offer in the region.”.

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Drug Discovery World

MAY 9, 2023

Jantzen Sperry , PhD, Director of Scientific Operations at Certis Oncology looks at how the adoption of orthotopic PDX models can elevate the impact of cancer research and improve translation in oncology drug development. Fewer than 5% of oncology drugs that enter clinical trials in the US receive US FDA approval.

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Drug Discovery World

MARCH 2, 2023

AI is revolutionising clinical trials and drug developments just as it is transforming other sectors, but in order for AI to make progress in rare diseases, the UK needs further investment to increase uptake and use. Changing the business model behind drug development is the first step. This needs to change.

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PPD

SEPTEMBER 25, 2023

As the clinical trial landscape evolves, drug developers are faced with novel challenges and changes in study recruitment, trial size and structure, and more. The adoption of new innovations, strategies and technologies offers opportunities to address persistent challenges and develop suitable approaches for the future.

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Drug Discovery World

JUNE 2, 2023

Download this exclusive eBook to learn more about: The latest advancements in artificial intelligence How machine learning is being used across cancer research Why AI is critical to solving challenges in drug discovery How AI can improve drug development for rare diseases The post AI and drug development: Using AI and machine learning to expedite drug (..)

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Drug Discovery World

APRIL 17, 2023

The speakers outline how TSAs can be used throughout the drug discovery and development pathway and offer examples of best practice and potential next steps. You can also find The Drug Discovery World Podcast on Spotify , Google Play and Apple Podcasts.

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Fierce BioTech

SEPTEMBER 19, 2023

To predict whether new therapeutics will be safe and effective for humans, drug developers first test them in animal- and cell-based models as well as computational tools that are designed to appro | An introduction to Organ-on-a-Chip technology and how it can improve the quality of drugs entering the clinic.

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DS in Pharmatics

APRIL 29, 2024

Creating a new drug involves a process that takes a lot of time and effort. When we think about drug development, it can be easy to generalize this procedure and assume that it can be approved rather quickly. However, the timeline for this approval could require you to wait between […]

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Drug Discovery World

OCTOBER 9, 2023

Hinshaw also played a key role on the Global Oncology Executive Committee, including leading key strategic programmes to maximise the portfolio and pipeline development. The post Long Covid: A call to action for drug developers appeared first on Drug Discovery World (DDW).

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Drug Discovery World

SEPTEMBER 12, 2022

The post New solution to boost RNA drug development appeared first on Drug Discovery World (DDW). “Covid vaccines were really just the beginning –- as we put more tools in the hands of scientists to help support their RNA therapeutics R&D, this field will really take off.”.

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Drug Discovery World

NOVEMBER 29, 2022

With our technology, it is possible to develop and manufacture proteins much more efficiently so that they can be marketed,” added Zelezniak. . . The post Researchers teach AI to tailor artificial DNA for drug development appeared first on Drug Discovery World (DDW).

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Drug Discovery World

NOVEMBER 23, 2022

The CoE aims to develop best practices and guidelines to use social media analysis as RWD for patient-focused drug development. While there is a concise regulatory framework on many sources of RWE for drug approval and Health Technology Assessments (HTA), this guidance is lacking for social media. “We

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Alta Sciences

APRIL 11, 2024

What does change in drug development look like? aasimakopoulos Thu, 04/11/2024 - 23:52 HTML Disrupting the CRO Model: A 2024 Global Health Summit Documentary Can the drug development industry change for the better? Contact us to get started! What is the Global Health Summit?

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Broad Institute

DECEMBER 18, 2023

Brain disorders are difficult to study and many drug candidates have failed in clinical trials, causing pharmaceutical companies to reduce their investments or even exit the field entirely.

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FDA Law Blog: Drug Discovery

MAY 1, 2024

proudly announces the return of attorney Sarah Wicks to its drug development and compliance group. Sarah brings a wealth of experience and a proven track record of advising innovative drug and biologics companies through the intricate landscape of product development and commercialization.

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BioPharma Drive: Drug Pricing

NOVEMBER 13, 2023

How can these increase the probability of success or efficiency in a pre-clinical and clinical drug development program? Regulatory agencies have set the framework and use cases for RWE.

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Drug Discovery World

JANUARY 24, 2023

The post AI and wearable tech could speed up drug development appeared first on Drug Discovery World (DDW). In addition, the technology allows to study patients across life-changing disease events such as loss of ambulation whereas current clinical trials target either ambulant or non-ambulant patient cohorts.

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