Fierce BioTech

SEPTEMBER 25, 2023

Biology Informatics Solutions Brochure From Assay Development Through Large Molecule Development. Download now to discover how to control your laboratory workflows across various assay techniques, modalities, and data types. jpiatt Mon, 09/25/2023 - 10:13 From Assay Development Through Large Molecule Development.

Assay Development 52

Assay Development Laboratories 52

Drug Discovery World

FEBRUARY 22, 2023

In this episode, we hear from Ashwin Pillai, a Test Engineer 3 in HTS & Assay Development at Ginkgo Bioworks, a company whose mission is to make biology easier to engineer. This is episode three, Connecting lab automation to decision-making.

Assay Development 130

Assay Development Engineering Science Drugs 130

Drug Discovery World

FEBRUARY 22, 2023

In this episode, we hear from Ashwin Pillai, a Test Engineer 3 in HTS & Assay Development at Ginkgo Bioworks, a company whose mission is to make biology easier to engineer. This is episode three, Connecting lab automation to decision-making.

Assay Development 130

Assay Development Engineering Science Drugs 130

Drug Discovery World

SEPTEMBER 5, 2023

Joining CN Bio in 2015, he was promoted to Director of Biology in 2018 with responsibility for biological assay development and collaborative research projects. Dr Tomasz Kostrzewski, Chief Scientific Officer, CN Bio Kostrzewski has more than 15 years of experience in molecular and cellular biology research.

Assay Development 147

Assay Development Drugs Pharmaceuticals International 147

Drug Discovery World

FEBRUARY 5, 2024

The company’s latest product introductions include the launch of its LabChip AAV empty/full characterisation solution, which is intended for adeno-associated virus (AAV) analysis to help streamline gene therapy development and manufacturing.

Small Molecule 162

Small Molecule Assay Development Production Science 162

Drug Discovery World

MAY 25, 2023

They are designed to streamline pre-clinical development of antibody-based therapeutics, enabling immunogenicity screening of drug candidates without the need for drug-specific ADA assay development.

Production 130

Production DNA Assay Development Drugs 130

Zobio

FEBRUARY 8, 2024

ZoBio was represented by Pim de Vink (Scientist, Assay Development and Screening) who presented poster Screening for Fragment Molecular. The meeting focused on case studies in Fragment-based Drug Discovery that have delivered compounds to late stage medicinal chemistry, preclinical or clinical programs.

Assay Development 40

Assay Development Drugs 40

Zobio

FEBRUARY 8, 2024

ZoBio was represented by Pim de Vink (Scientist, Assay Development and Screening) who presented poster Screening for Fragment Molecular. The meeting focused on case studies in Fragment-based Drug Discovery that have delivered compounds to late stage medicinal chemistry, preclinical or clinical programs.

Assay Development 40

Assay Development Drugs 40

PPD

OCTOBER 18, 2023

With the depth of knowledge to support all types of pharmaceutical products across all phases of development, we provide services ranging from end-to-end assay development to platform expansion, designed with the client’s timeline and budget in mind. Stay ahead of the curve with a great GMP/CMC contract laboratory partner.

Laboratories 52

Laboratories Assay Development Small Molecule Packaging 52

Drug Discovery World

FEBRUARY 6, 2024

These events feature presentations by leading experts in various aspects of drug discovery, covering topics such as target identification and validation, high-throughput screening, assay development, and data analysis. Researchers gain insights into the latest trends, methodologies, and discoveries shaping the field.

Medical Schools 147

Medical Schools Clinical Trials Assay Development Hospitals 147

Sygnature Discovery

FEBRUARY 11, 2022

This exciting partnership combines our novel assay development and hit identification expertise with River BioMedics unique, state-of-the-art technology: advanced human-predictive in vitro 3D heart models, plus their deep knowledge of cardiac biology.

Assay Development 52

Assay Development Engineering Disease Science 52

Broad Institute

OCTOBER 17, 2023

He utilized industry-leading laboratory technology to design robust, repeatable experiments, including assay development, training, large screens, and follow-up assays. Soule holds a B.S. in mechanical engineering from Boston University. Contact Christian Soule via email at chsoule@broadinstitute.org.

Assay Development 52

Assay Development Laboratories Engineering Science 52

Drug Discovery World

SEPTEMBER 29, 2022

During a 2021 webinar on optimising assay development for hit identification, a survey asked over 50 drug discovery scientists, “Which goal is the highest priority when developing a drug discovery assay?”. Three common questions regarding the challenges when considering outsourcing partners for drug discovery.

Small Molecule 130

Small Molecule Assay Development DNA Biochemical Assays 130

Drug Discovery World

JUNE 30, 2023

The combination of bit.bio’s human disease cells and Charles River Assay Development Services provide access to reproducible cell populations and robust assay quality. This approach to cell differentiation generates high-purity, mature, consistent, and scalable human cell lines.

Drug Development 130

Drug Development Drugs Assay Development Disease 130

Drug Discovery World

JUNE 12, 2023

Those are the beginning of additional manufacturing, scale of chemistry pharmacokinetics, pharmacology assays, development bioanalytical assays, and then moving forward toxicology work to start the initial clinical trials. Then, we move forward with what are called Investigational New Drug enabling studies.

Research 130

Research Clinical Trials Doctors Assay Development 130

Sygnature Discovery

SEPTEMBER 14, 2023

Programs have integrated Sygnature’s novel assay development and hit identification expertise with River BioMedics’ unique, state-of-the-art technology to advance human-predictive in vitro 3D heart models and its deep knowledge of cardiac biology. The two companies have collaborated in cardiovascular drug discovery since March 2021.

Small Molecule 52

Small Molecule Assay Development Disease Drug Research 52

Drug Target Review

JUNE 15, 2023

Sam focuses on the application of innovative assay development strategies to enable to interrogation of complex targets. As a postdoc, Sam trained with Richard Youle and Jim Inglese at the National Institutes of Health where he first realised the potential of genome editing in drug discovery.

RNA 96

RNA Small Molecule Disease Assay Development 96

Alta Sciences

AUGUST 21, 2023

Our solutions include standalone services or integrated programs, providing assay development and top-quality data for toxicokinetic (TK) , pharmacokinetic (PK), and pharmacodynamic (PD) determinations to support your nonclinical and clinical studies. Why Partner With Altasciences for Your Bioanalytical Projects?

Assay Development 52

Assay Development Pharmacokinetics Drug Development Research 52

Drug Discovery World

OCTOBER 13, 2022

Meanwhile, Stratech Bio were on hand to answer enquiries about their range of raw materials, kits and assays for R&D or bioprocessing projects. Over at LabLogic, product specialists were on hand to share expertise and solutions, and gave a brief talk in Auditorium 1 to give an overview of the LabLogic products.

Drugs 130

Drugs Cell Based Assays Science Assay Development 130

Sygnature Discovery

JANUARY 17, 2023

About SB Drug Discovery SB Drug Discovery is an industry leader in specialist contract research, providing critical data for novel drug development through cell line generation, assay development and compound screening services. SB is based in Glasgow and employs 55 people.

Compound Screening 52

Compound Screening Marketing Assay Development Drugs 52

The Pharma Data

SEPTEMBER 8, 2021

TIB Molbiol excels in ultra-rapid assay development for emerging infectious disease, strongly demonstrated during the COVID-19 pandemic. The acquisition enables Roche to further expand the portfolio of currently over 45 CE-IVD assays and more than 100 research use assays on Roche`s LightCycler PCR instruments.

Virus 52

Virus Assay Development Disease Research 52

PerkinElmer

NOVEMBER 12, 2020

These are just three of the steps to take toward reliable and replicable assay development. The post Replicable Assays: Not the Impossible Dream first appeared on PerkinElmer Blog. It’s also important to consider if plates will be compatible with your lab’s current screening instrumentation. You can find the entire list here.

Assay Development 52

Assay Development Drug Development Research Marketing 52

FDA Law Blog: Drug Discovery

JANUARY 4, 2023

The Agency recommended that product developers begin designing potency assay(s) early, and developing and evaluating multiple potency assays since not all potency assays can be validated and some potency assays may not fully reflect the biological activity.

Therapies 59

Therapies Engineering Production FDA 59

Drug Target Review

NOVEMBER 1, 2023

We support the drug discovery projects of the CCDD with assay development and screening, biophysics, structural biology and recombinant protein production. Although we are an academic centre we work very much like industry. The team that I lead within the CCDD is called the Hit Discovery and Structural Design Team.

Fragment Screening 96

Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96

Drug Discovery World

APRIL 3, 2023

To support this, we have recently introduced an assay development team that can validate the binders in the specific end-application required by the customer, whether this is IHC, ELISA assays or demonstration of gene therapy delivery and function in vitro.

Science 130

Science Molecular Biology Therapies Small Molecule 130

Drug Discovery World

MARCH 4, 2024

DDW Editor Reece Armstrong speaks to Abraham Wang , Head of Marketing at Collaborative Drug Discovery (CDD) about annotated assays and the advantages they bring to research teams. RA: What advantages can better analysis into assays bring to drug developers?

Drugs 147

Drugs Drug Development Compliance Research 147

Drug Discovery World

DECEMBER 14, 2023

In a DDW Sitting Down With podcast with Diana Spencer, Charles Powell , CEO of Aurora Microplates, discusses how microplate technology has evolved to keep up with changing trends in drug discovery and why this ubiquitous, almost invisible, tool can have a huge impact on the reliability of scientific investigations.

Laboratories 130

Laboratories Production Science Packaging 130

Drug Discovery World

FEBRUARY 7, 2023

A new collaboration aims to accelerate development of advanced G-protein coupled receptor (GPCR)-targeting therapeutics for cachexia caused by cancer and other chronic conditions.

Cell Based Assays 130

Cell Based Assays International Drug Development Trials 130

Drug Discovery World

OCTOBER 11, 2022

Assay development meets high dimensional experimentation (HDE). across their assay development teams. Used consistently, the potential impact of HDE on assay development is huge: Higher assay quality. Lower assay cost. Faster time-to-insight. This is an early indication of what’s to come.

Assay Development 130

Assay Development Science Engineering Drugs 130

Drug Discovery World

APRIL 21, 2023

High content screening: an introduction to instrumentation, assay development, screening, image and data analysis: Eberhard Krausz, Short Course Instructor from ChemBioCon in Belgium, will be running a half-day course that provides an introductory level overview of the state-of- the-art components of HCS including the wide variety of imagers, good (..)

Cell Based Assays 130

Cell Based Assays Targeted Protein Degradation Assay Development Doctors 130

Drug Discovery World

DECEMBER 28, 2022

The use of biomarkers in biotherapeutic development continues to increase. The introduction of plug and play kits is designed to increase the utility of the platform by removing the timelines needed for assay development. . Asteria Benchtop Kit and the Cytonaut Cloud Analysis Software – Scipio bioscience .

Production 242

Production Compliance Assay Development RNA 242

Drug Discovery World

JANUARY 19, 2023

Fully integrated pDNA services Catalent uses a flexible approach to support innovators which can begin at the lead identification step (including the development of E. coli cell lines), or later in the process using existing GMP cell banks for programs that have already completed early phase trials, for example.

DNA 130

DNA Therapies Assay Development Production 130

Drug Discovery World

FEBRUARY 21, 2023

Ashwin Pillai is Test Engineer 3 in HTS & Assay Development at Ginkgo Bioworks, a company whose mission is to make biology easier to engineer. Ahead of his presentation in the Automation Technologies Track at SLAS2023, Pillai shares insight on data and how we can connect lab automation to decisions.

Bioinformatics 130

Bioinformatics Assay Development Engineering Drugs 130

The Pharma Data

MARCH 20, 2021

A schematic of domain and functional organization of two of the major structural proteins of SARS-CoV-2, Nucleocapsid protein as a target viral antigen for assay development. Based on our discovery experiments, we decided upon nucleocapsid protein as our target antigen for assay development.

Virus 52

Virus Assay Development Laboratories RNA 52

Agency IQ

JULY 21, 2023

With this in mind, FOCR will work over the next few years to “establish evidence of baseline ctDNA levels by cancer type and stage across assays through a collaborative effort with multiple assay developers.”

FDA 40

FDA Clinical Trials DNA Treatment 40

Drug Discovery World

MAY 11, 2023

This approval could pave the way for LC-MS to transition more frequently into a good manufacturing process (GMP) environment, where it can be used as a release assay for regulatory documentation. LC-MS can prove valuable not only in quality control, but also in early development phases.

Production 130

Production Vaccine Immune Response Therapies 130

Drug Discovery World

APRIL 25, 2024

Reece Armstrong offers an overview of cell line development and outlines the benefits the technology is bringing to biopharmaceutical developers. Cell line development is an essential underpinning of the drug development process, enabling teams to test, optimise and manufacture therapeutics at a commercial scale.

Vaccine 147

Vaccine Production Pharmaceuticals Therapies 147