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Biochemical assays and deep cyclic inhibition in cancer treatment

Drug Target Review

Molecular-level biochemical assays like transcriptomics, genomics and proteomics have emerged as valuable tools for identifying potential targets in cancer treatment through deep cyclic inhibition (DCI).

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Positive Impact of Dragonfly™ Discovery in Biochemical Assay

Zobio

Biochemical assays are commonly used to assess how organic compounds impact the activity of a protein of interest (POI). Het bericht Positive Impact of Dragonfly™ Discovery in Biochemical Assay verscheen eerst op ZoBio - Drug Discovery Technology.

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Evaluation of a panel of furochromenones as the activator and inhibitor of tyrosinase

Chemical Biology and Drug Design

Using fungal tyrosinase-based in vitro biochemical assay, we obtained one compound ( 3k ) which could inhibit tyrosinase activity, and the other compound ( 4f ) that stimulated tyrosinase activity. In the present study, we investigated these compounds for their potential as antagonists or agonists of tyrosinase.

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A Guide to DNA Damage Response and Innate Immunity

Drug Target Review

The Transcreener HTS Assay platform accelerates these efforts by providing robust and easy-to-use biochemical assays for key enzymes in the pathways. In this guide, we provide an overview of the DDR and innate immune pathways and describe assay systems for key therapeutic targets.

DNA 104
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Betulinic acid reduces inflammation in rats with sepsis?induced myocardial dysfunction by inhibiting TLR4/MyD88/NF??B signaling pathway

Chemical Biology and Drug Design

Then, cardiac function parameters were assessed using echocardiography, myocardial injury markers were quantified via biochemical assays, and myocardial histopathological injuries were observed through H&E staining.

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The future of cancer immunotherapy: exclusive webinar

Drug Discovery World

Veronique Baron from BPS Bioscience discusses the tools required to research and develop new oncology therapies, such as proteins, antibodies, cell lines, assay kits and viral tools. In another presentation, Dr Hengshuo Liu from ACROBiosystems will examine the areas where proteins and innovation are advancing biomedicine.

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Learn about cancer immunotherapy in this webinar

Drug Discovery World

Veronique Baron from BPS Bioscience discusses the tools required to research and develop new oncology therapies, such as proteins, antibodies, cell lines, assay kits and viral tools. In another presentation, Dr Hengshuo Liu from ACROBiosystems will examine the areas where proteins and innovation are advancing biomedicine.