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CAR-T therapy could “alter the treatment paradigm” of multiple sclerosis

Drug Discovery World

. “This approval is a critically necessary step that paves the way to enrol patients with treatment-refractory progressive MS for whom there are no currently available treatment options in the KYSA-7 trial.

Therapies 312
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Potent drug candidate could transform liver disease treatment

Drug Discovery World

Scientists from Gwangju Institute of Science and Technology in Korea have discovered compound 11c, a potentially ground-breaking oral treatment for metabolic dysfunction-associated steatohepatitis. The post Potent drug candidate could transform liver disease treatment appeared first on Drug Discovery World (DDW).

Disease 130
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Phase I study to evaluate treatment of worsening heart failure 

Drug Discovery World

Corteria Pharmaceuticals has initiated a Phase I study to evaluate the company’s first-in-class corticotropin-releasing hormone receptor 2 (CRF2) agonist, COR-1167, for the treatment of Worsening Heart Failure (WHF). The post Phase I study to evaluate treatment of worsening heart failure appeared first on Drug Discovery World (DDW).

Treatment 130
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Treatment potential for immunotherapy-induced cytokine release syndrome  

Drug Discovery World

Cancer immunotherapies, such as bispecific antibodies and CAR-T cell therapy, are rapidly moving into earlier lines of treatment in many tumour types, with these markets anticipated to grow to US$100bn+ (~35% CAGR) by 2030 3. In the US, the American Cancer Society estimates that there will be 24.6 million cases of cancer by 2030 1,2.

Treatment 162
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“Highly encouraging” results for treatment-resistant schizophrenia drug

Drug Discovery World

Milan-based Newron Pharmaceuticals has reported “exceptional” one-year results from study 014/15 into evenamide as an add-on to antipsychotics for the management of treatment-resistant schizophrenia (TRS). The post “Highly encouraging” results for treatment-resistant schizophrenia drug appeared first on Drug Discovery World (DDW).

Treatment 147
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FDA approves new treatment option for anaemia due to kidney disease

Drug Discovery World

The US Food and Drug Administration (FDA) has approved Vafseo (vadadustat) Tablets for the treatment of anaemia due to chronic kidney disease (CKD) in adults who have been receiving dialysis for at least three months. Vafseo is now approved in 37 countries.

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Partnership to advance personalised treatments for long Covid

Drug Discovery World

PrecisionLife and the Metrodora Institute have agreed a partnership to jumpstart the diagnosis and treatment options for a range of complex, chronic diseases. In Metrodora we have a partner that is focused on the diagnosis and treatment of some of the most challenging and intractable diseases,” said Steve Gardner, PrecisionLife’s CEO.

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