Drug Target Review

JUNE 30, 2025

The integration of machine learning enables the team to predict which novel proteins are most likely to play critical roles in disease – all before any laboratory work begins. This approach accelerates discovery by focusing experimental efforts where the data suggests the highest potential impact.

Disease 59

Disease Medical Schools Science Therapies 59

Broad Institute

OCTOBER 29, 2024

Previous clinical and laboratory studies on other MCL1 inhibitors have suggested that these molecules can impair heart cells, likely because of prolonged exposure to the compounds. The compound inhibited the growth of a broad range of cancer models, including breast cancer, lung cancer, melanoma, sarcoma, lymphoma, and leukemia.

Drugs 133

Drugs Small Molecule Pharmacokinetics Clinical Trials 133

BMG Labtech

DECEMBER 20, 2024

Knowledge of metabolic control in bacteria is not only important for practical applications in biotechnology , medicine, and the environmental sciences but is also a foundation for fundamental research in laboratories across the globe. Measurement of bacterial growth based on optical density (OD 600 ) is frequently used in many laboratories.

Regulations 52

Regulations Laboratories Research Production 52

Drug Target Review

JUNE 16, 2025

For good laboratory practice (GLP) studies, project teams may consider freezing select tissue blocks for MSI under a non-GLP protocol. He went on to complete postdoctoral studies in Professor Gary Keck’s laboratory at the University of Utah, where he investigated mechanisms of stereoselective reactions.

Drugs 52

Drugs Organic Chemistry Laboratories Pharmaceuticals 52

Drug Target Review

APRIL 30, 2025

Its AI platforms are designed specifically for CGT, capable of handling complex biological data, integrating with laboratory and manufacturing systems, and adapting to evolving research and clinical needs. These solutions were designed for standardised processes and fail to manage the dynamic, high-variability data unique to living therapies.

Drugs 90

Drugs Therapies Clinical Trials Trials 90

The Pharma Data

JUNE 23, 2025

Dr. Joerg Koglin, senior vice president and head of general and specialty medicine at Merck Research Laboratories, echoed this sentiment, stressing the broad potential impact of the therapy. “To We thank all study participants for being part of this important study.”

Trials 40

Trials Therapies Treatment Disease 40

Drug Target Review

JUNE 14, 2025

In the rapidly evolving landscape of life sciences, the communication gap between laboratory scientists and data scientists remains a significant challenge. However, they recognised that data science and AI were becoming increasingly important, not only within laboratories but also within automation.

Laboratories 69

Laboratories Science Bioinformatics Molecular Biology 69

Sygnature Discovery

JULY 24, 2025

Sygnature Discovery, a leading integrated drug discovery contract research organisation (CRO), today announces the completion of a major enhancement to its high-throughput chemistry (HTC) capabilities and laboratory infrastructure following a £1 million investment.

Laboratories 52

Laboratories Disease Science Drugs 52

Alta Sciences

JUNE 6, 2025

Optimizing Tube Labeling for Improved Efficiency The tube labeling process starts with the generation of an Excel file generated from our Laboratory Information Management System (LIMS), which contains a list of unique IDs and sample information. This file is then imported into an MS App interface to create the user request.

Pharmacokinetics 52

Pharmacokinetics Molecular Biology Drug Development Pharmaceutical Companies 52

The Pharma Data

JUNE 18, 2025

Dr. Marjorie Green, Senior Vice President and Head of Oncology Global Clinical Development at Merck Research Laboratories, emphasized the significance of this new trial within the broader scope of the ADC’s development.

Trials 40

Trials Therapies Clinical Trials Treatment 40

Drug Target Review

JULY 7, 2025

Guide for the Care and Use of Laboratory Animals. NIH Office of Laboratory Animal Welfare – Training Guidelines. Alternatives to Laboratory Animals , 50(3). Federal ruling on USDA primate welfare petition, 2023. National Research Council. European Directive 2010/63/EU on the protection of animals used for scientific purposes.

Drug Research 52

Drug Research Research Animal Testing Drugs 52

The Pharma Data

JUNE 24, 2025

With Bio-Techne’s global distribution network and integrated analytical platforms like the MauriceFlex™, more laboratories can now seamlessly adopt these standards into their workflows.

Therapies 40

Therapies Biosimilars Compliance Virus 40

Drug Target Review

JUNE 26, 2025

In the rapidly evolving landscape of life sciences, the communication gap between laboratory scientists and data scientists remains a significant challenge. This represents another skill we’re asking laboratory scientists to develop. This ‘silo problem’ can impede innovation and slow down research progress.

Laboratories 52

Laboratories Science Molecular Biology Bioinformatics 52

Drug Target Review

JUNE 19, 2025

SRP-001 has already moved beyond the laboratory. Bazan sees it as part of a broader shift towards combination therapies – an approach that will likely define the next generation of pain management. From bench to bedside: what is next?

Clinical Trials 52

Clinical Trials Molecular Biology Treatment Trials 52

The Pharma Data

JUNE 15, 2025

Furthermore, QIAGEN will validate the diagnostic panel’s performance and robustness, ensuring its utility across a range of laboratory settings. This diagnostic panel will aid clinicians in guiding their treatment decisions by identifying the patients most likely to respond to Incyte’s innovative therapy.

Disease 40

Disease Therapies Treatment Laboratories 40

Broad Institute

JUNE 24, 2025

Based on a technology developed by Broad Institute core member David Liu’s laboratory, the treatment is the first in a series of new medicines being tested to treat rare diseases by repairing patients’ particular genetic misspellings. The team that treated K.J.

Treatment 133

Treatment Disease DNA Clinical Trials 133

Quanticate

JUNE 13, 2025

Clinical research generates vast amounts of diverse data from laboratory tests, patients, medical equipment, and outside sources. By organising and analysing this information, researchers can extract actionable insights that improve patient outcomes, data accuracy, drug efficacy and speed up trials.

Clinical Trials 52

Clinical Trials Trials Laboratories Clinical Research 52

The Pharma Data

JUNE 18, 2025

By bringing research and clinical development under one organizational roof, Alnylam aims to accelerate its ability to turn laboratory discoveries into life-saving treatments.

RNA 40

RNA Clinical Development Science Disease 40

PPD

JANUARY 15, 2025

Using patient-centered strategies and data analytics, our capabilities cover multiple therapeutic areas and include early development, all phases of clinical development, peri- and post-approval, novel approaches to patient recruitment and investigator sites and comprehensive laboratory services. Get in touch.

Clinical Trials 95

Clinical Trials Trials Clinical Research Drug Development 95

The Pharma Data

JUNE 13, 2025

The two companies have signed a Memorandum of Understanding (MoU) to provide comprehensive support and resources to Japanese drug-discovery startups, helping them bring their innovations from laboratory benches toward eventual global delivery of new medicines.

Research 40

Research Government International Pharmaceutical Companies 40

The Pharma Data

JULY 2, 2025

Due to the severity of these risks, Lynozyfic is distributed under a Risk Evaluation and Mitigation Strategy (REMS) program.

FDA 40

FDA FDA Approval Therapies Treatment 40

Drug Target Review

MAY 14, 2025

What makes this an exciting time is that laboratory automation technology has matured significantly in recent years. When predictions concern biology which is inherently complex it takes time to cultivate cells and can be expensive to generate sufficient data. These two halves of the problem are coming together.

Drugs 69

Drugs Science Government Production 69

Broad Institute

APRIL 5, 2025

Since their initial development, both base editing and prime editing have been used by thousands of laboratories around the world and have enabled the study and potential treatment of many genetic diseases. The Breakthrough Prize is one of the worlds most important science awards.

Science 144

Science Clinical Trials DNA Disease 144

Alta Sciences

NOVEMBER 13, 2024

Their three state-of-the-art bioanalytical laboratories feature mirrored operations and uniform protocols to maintain consistency and quality across client projects, ensuring reliable, high-quality data regardless of location. Whether for preclinical or clinical studies, we provide tailored solutions to meet specific research needs.

Clinical Pharmacology 40

Clinical Pharmacology Laboratories Drug Development Pharmaceuticals 40

Broad Institute

JUNE 4, 2025

Presenter Lennart Nickel, Doctoral Assistant in the Laboratory of Protein Design & Immunoengineering at EPFL. Bindcraft Workshop By Rose Circeo June 4, 2025 Breadcrumb Home Bindcraft Workshop November 6, 2025 12:00-4:00 pm Workshop (lunch served) 4:00-5:00 pm Broad Institute museum tour Registration opens June 9.

Laboratories 52

Laboratories Doctors 52

Conversations in Drug Development Trends

JANUARY 21, 2025

Jayaprakash Kotha, MBBS, PhD, ASCP (SH), Vice President, Bioanalytical Laboratory Satish Kumar, MBB, Head of Process Improvement Continuous Innovation is a Cornerstone of Bioanalysis Approximately 80% of drugs that begin the research process fail to reach approval. What is one contributing factor that sets the 20% that do apart from the rest?

Clinical Trials 78

Clinical Trials Laboratories Trials Drug Development 78

The Premier Consulting Blog

OCTOBER 30, 2024

The I-TEAM Hub is a laboratory space specifically designed for FDA staff to have hands-on experience with various advanced technologies on which they would advise, e.g., AI/machine learning, 3D printing, etc. To support this, the Innovative Technologies and Advanced Manufacturing Hub (I-TEAM Hub) was created.

FDA 52

FDA Regulations Pharmaceuticals Production 52

The Pharma Data

JUNE 9, 2025

Li, President of Merck Research Laboratories, underscored the importance of this approval for the company’s pediatric infectious disease portfolio. Additional safety data are expected to be collected as ENFLONSIA is introduced into broader clinical use. A New Era in Infant RSV Protection Dr. Dean Y.

FDA Approval 40

FDA Approval FDA Hospitals Clinical Trials 40

Alta Sciences

JULY 18, 2025

We have state-of-the-art, purpose-built laboratories at our locations in the U.S. Following clear processes, in accordance with GLP and current FDA/EMA guidelines—and supported by our unique array of platforms and large list of validated assays —our team ensures the most effective methods for your individual programs.

Assay Development 52

Assay Development Small Molecule Laboratories Regulations 52

The Pharma Data

JUNE 26, 2025

This simplicity in dosing may help streamline clinical workflows and facilitate broader use in outpatient, hospital, and community health settings. Dr. Richard M.

Vaccine 52

Vaccine Hospitals Virus Clinical Trials 52

Drug Target Review

JUNE 19, 2025

His areas of expertise include protein and nucleic acid sample preparation, mass spectrometry, proteomics, glycomics, analytical chemistry, and laboratory equipment sales. Throughout his career, he has accumulated experience in sales and product management within the life science sector.

Analytical Chemistry 52

Analytical Chemistry Engineering Science Government 52

Codon

NOVEMBER 3, 2024

Working at the famed Pasteur Institute, the duo began by figuring out how best to culture mycobacteria — a seemingly simple, but essential first step, given how no one at the time had yet come up with an effective way of growing these bacteria in the laboratory. Many more could emerge as machine learning tools improve.

Vaccine 113

Vaccine Trials Therapies Treatment 113

Alta Sciences

JULY 9, 2025

In her current role, Kaylyn assists PCR scientists with their projects and helps them identify tools and craft custom laboratory solutions to meet sponsors’ needs. ABOUT THE AUTHOR: KAYLN KOENIG Kaylyn Koenig first joined Altasciences in 2019 as a scientist and was promoted to Principal Scientist in 2023.

Therapies 52

Therapies Molecular Biology Science RNA 52

The Pharma Data

JUNE 24, 2025

The goal is to transform laboratory discoveries into clinically relevant therapies that can reach patients faster and more efficiently. Meanwhile, research into neurology and rare diseases continues to be an area of unmet need where innovative science can deliver transformative solutions.

Pharma R&D 40

Pharma R&D Pharmaceutical Companies Pharmaceuticals Science 40

Alta Sciences

JULY 23, 2025

ALTASCIENCES’ FLOW CYTOMETRY SERVICES Our clinical facilities at Altasciences are integrated with state-of-the-art flow cytometry laboratories. We are all pushing the boundaries in terms of technology while acknowledging the importance of guidelines to ensure scientific reliability.

International 52

International Science Drug Development Laboratories 52

Advarra

JULY 3, 2025

Digital Tools: Is your protocol designed for remote care realities, such as remote monitoring, diagnostics, and laboratory logistics? Are they available in the correct language(s)? Are they written to meet patient comprehension levels?

Compliance 52

Compliance Trials Clinical Trials Laboratories 52

Alta Sciences

NOVEMBER 4, 2024

With airlocks around the manufacturing and laboratory areas, staff could safely gown and de-gown. These isolated suites feature containment systems for negative pressure controls to limit exposure, and for monitoring and verifying effectiveness of the containment strategies.

Engineering 52

Engineering Production Compliance Laboratories 52