addgene Blog

JULY 16, 2024

There are several facilities nationwide where you can obtain excellent quality, high titer rAAV ( including Addgene! ), but you can also generate rAAVs in your own lab with standard molecular biology tools and tissue culture experience. Here, we’ll go over the basics of rAAV production.

Molecular Biology 52

Molecular Biology Production 52

Drug Discovery World

JUNE 13, 2024

This free event will feature insight from Thermo Fisher Scientific’s Jonas Buege, Senior Manager, Product Management, as well as Viki Mahen, Scientist III, Molecular Biology.

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DNA Molecular Biology Compliance Production 130

Drug Discovery World

JUNE 6, 2024

This free event will feature insight from Thermo Fisher Scientific’s Jonas Buege, Senior Manager, Product Management, as well as Viki Mahen, Scientist III, Molecular Biology.

DNA 130

DNA Molecular Biology Compliance Production 130

Drug Discovery World

MAY 30, 2024

This free event will feature insight from Thermo Fisher Scientific’s Jonas Buege, Senior Manager, Product Management, as well as Viki Mahen, Scientist III, Molecular Biology.

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DNA Molecular Biology Compliance Production 130

Drug Discovery World

DECEMBER 20, 2023

Lead author Professor Clare Isacke, Professor of Cell Molecular Biology and Dean of Academic and Research Affairs at the ICR, said: “This work has achieved significant insights into breast cancer metastasis to the leptomeninges, which has been relatively unstudied to date.

Molecular Biology 264

Molecular Biology DNA Drugs Treatment 264

SCIENMAG: Medicine & Health

JUNE 13, 2023

A new paper in Molecular Biology and Evolution, published by Oxford University Press, shows that a condition known as Dupuytren’s disease is partly of Neandertal origin. Credit: Hugo Zeberg/ Molecular Biology and Evolution A new […]

Molecular Biology 83

Molecular Biology Disease Research 83

Drug Discovery World

DECEMBER 21, 2022

It covers an article by the same name written for Volume 23, Issue 1 – Winter 2021/22 of DDW.

Molecular Biology 130

Molecular Biology Drugs Science Treatment 130

Drug Discovery World

APRIL 17, 2024

It will be presented by Dylan Mooijman, Head of R&D, Single Cell Discoveries and Darina Šikrová, Researcher, Molecular Biology, Single Cell Discoveries. The event will take place on 25 April 5 PM BST / 6PM CEST / 9AM PST. It will also feature an introduction by Melanie Masuda, Director of Market Development, ScaleBio.

Molecular Biology 130

Molecular Biology RNA Drugs Research 130

Drug Discovery World

APRIL 3, 2024

It will be presented by Dylan Mooijman, Head of R&D, Single Cell Discoveries and Darina Šikrová, Researcher, Molecular Biology, Single Cell Discoveries. The event will take place on 25 April 5 PM BST / 6PM CEST / 9AM PST. It will also feature an introduction by Melanie Masuda, Director of Market Development, ScaleBio.

Molecular Biology 130

Molecular Biology RNA Drugs Research 130

SCIENMAG: Medicine & Health

FEBRUARY 6, 2024

Dr. Wu is an associate professor in the Department of Molecular Biology at the University of Texas Southwestern Medical Center, U.S.A. Evanston, IL—The International Society for Stem Cell Research (ISSCR) is honoring Jun Wu, Ph.D. with the 2024 ISSCR Outstanding Young Investigator Award. Credit: ISSCR Evanston, IL—The […]

Molecular Biology 83

Molecular Biology International Research 83

Drug Discovery World

MARCH 21, 2024

The project will be led by Søren Lykke-Andersen, a Senior Scientist at Aarhus University (AU), working at the Department of Molecular Biology and Genetics.

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RNA Molecular Biology Laboratories Engineering 130

Drug Discovery World

MAY 17, 2023

The study was conducted by researchers at the Universities of Bristol (UK) and Queensland (Australia), and the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK.

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Disease Molecular Biology Laboratories Virus 130

SCIENMAG: Medicine & Health

SEPTEMBER 7, 2023

Details on the findings, which were reported in the September 7 issue of Nature Structural & Molecular Biology [DOI: 10.1038/s41594-023-01085-6], could […]

Molecular Biology 96

Molecular Biology Drugs Research 96

SCIENMAG: Medicine & Health

JULY 4, 2023

The European Molecular Biology Organization (EMBO) has announced today that it will award the lifetime honor of EMBO Membership to Luísa Figueiredo, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM, Lisbon, Portugal), in recognition of the excellence of her research and outstanding achievements in the life sciences.

Molecular Biology 90

Molecular Biology International Science Research 90

Drug Discovery World

JUNE 2, 2023

The Flex robot’s modular hardware and software tools can simplify lab automation, reduce errors, and make reproducible research possible, for the field of molecular biology in particular. “By making lab automation as easy as using a smartphone, the Flex robot democratises access to automation in life sciences research.”

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Molecular Biology Laboratories Science Research 130

Drug Discovery World

OCTOBER 3, 2022

in Chemical Biology. She completed her academic training with a post-doctoral career development fellowship in Protein Engineering at the MRC Laboratory of Molecular Biology in Cambridge, UK. Hammerstein graduated from the University of Oxford with a M.Chem. in Chemistry and D.Phil.

Molecular Biology 244

Molecular Biology Biosimilars Laboratories Doctors 244

Drug Discovery World

DECEMBER 21, 2022

It covers an article by the same name written for Volume 23, Issue 1 – Winter 2021/22 of DDW.

Molecular Biology 130

Molecular Biology Drugs Science Treatment 130

biobide

NOVEMBER 24, 2023

In the realm of molecular biology and toxicology, the terms "genotoxicity" and "mutagenicity" are often used interchangeably, but they refer to distinct concepts with unique implications. Understanding these differences is crucial for assessing the potential risks associated with various substances and environmental factors.

Molecular Biology 64

Molecular Biology 64

Covalent Modifiers

MARCH 30, 2024

Lingyang Kong, Sang-Jun Park Wonpil Im Journal of Molecular Biology , 2024 [link] Molecular modeling and simulation serve an important role in exploring biological functions of proteins at the molecular level, which is complementary to experiments.

Molecular Biology 81

Molecular Biology Drugs 81

Drug Discovery World

FEBRUARY 8, 2024

Dr O’Hara began by recognising the challenges associated with AAV therapeutic development, e.g., how plasmids are difficult to synthesize, amplify, and analyse with standard molecular biology protocols.

Therapies 147

Therapies Bioinformatics Packaging Molecular Biology 147

Broad Institute

DECEMBER 13, 2023

Hung Group, Infectious Disease and Microbiome Program Michael Bogaev Princeton University Molecular Biology (major), B.A., Spanish (minor) Genetic Pertubation Platform (GPP) Mohammed Mutaher Harvard University Human Developmental and Regenerative Biology (major), B.A.,

Molecular Biology 52

Molecular Biology Cell Biology Engineering Science 52

Drug Discovery World

MARCH 12, 2024

In the future, the combination of CAR T-cell therapy with local small molecules, such as BioSenic’s arsenic trioxide, may be a combinatorial strategy to overcome the limitations of each monotherapy.” Richard Hammond, CTO, Sphere Fluidics “The development of mAb-based therapies has rapidly taken off within the last few decades due to advances (..)

Molecular Biology 204

Molecular Biology Small Molecule Therapies FDA Approval 204

addgene Blog

JULY 27, 2023

The Retroviridae (commonly called retrovirus) family — of which HIV is a member — may seem like an unlikely candidate to use as a viral vector, but retroviruses have been developed into some of the most widely used tools in molecular biology. Retroviruses” is an umbrella term which encompasses 1.)

Molecular Biology 69

Molecular Biology 69

Drug Discovery World

OCTOBER 11, 2023

Dr Michael Seiler, Vice President of Commercial Products, Taconic: A trained immunologist, Dr Seiler earned his PhD in cell and molecular biology at the Baylor College of Medicine and worked in the lab of renowned immunologist Dr Albert Bendelac at the University of Chicago.

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Research Molecular Biology RNA Engineering 130

Broad Institute

JULY 17, 2024

As of now, papers describing three of these machine learning tools have been published, in the Journal of Chemical Information and Modeling , Molecular Biology of the Cell , and Chemical Research in Toxicology. Molecular Biology of the Cell. A fourth is in the works. DOI: 10.1021/acs.chemrestox.4c00015. Seal S, et al.

Pharmacokinetics 80

Pharmacokinetics Molecular Biology Drugs FDA 80

Broad Institute

APRIL 22, 2024

Jennifer's research interests are broadly at the intersection of machine learning, applied statistics, molecular biology and science. She has two undergraduate degrees, one in Physics and one in Computer Science, from Queen's University in Canada. Previous Jenn Nava Next Jesse Boehm

Molecular Biology 52

Molecular Biology Engineering Science Research 52

SCIENMAG: Medicine & Health

AUGUST 3, 2023

In a study published today in Cell, one of the most prominent peer-reviewed scientific journals in the field of Biochemistry & Molecular Biology, scientists from the National University of Singapore (NUS) and Imperial College London have discovered a new way by which bacteria transmit their genes, enabling them to evolve much faster than previously (..)

Virus 60

Virus Molecular Biology 60

Drug Discovery World

OCTOBER 3, 2023

Dr O’Hara began by recognising the challenges associated with AAV therapeutic development, e.g., how plasmids are difficult to synthesise, amplify, and analyse with standard molecular biology protocols.

Therapies 130

Therapies Bioinformatics Packaging Molecular Biology 130

Drug Discovery World

OCTOBER 24, 2023

MP : Lithuania is a hub of gene editing, as we not only have the Life Sciences Centre at Vilnius University, but also the European Molecular Biology Laboratory (EMBL). DS: What was the motivation for launching Caszyme and what challenges did you face creating a viable business?

Science 263

Science Molecular Biology Government Regulations 263

Chemical Biology and Drug Design

DECEMBER 6, 2023

However, the pharmacodynamic mechanism and molecular target of SP-FC in the treatment of HS are still unclear. Therefore, this study is intended to explore the mechanism and target of SP-FC in the treatment of HS through network pharmacology combined with in vitro cell and molecular biology experiments.

Molecular Biology 100

Molecular Biology Protein Expression Treatment Regulations 100

Drug Target Review

NOVEMBER 23, 2023

About the author Dr William Schafer Group Leader at MRC Laboratory of Molecular Biology William Schafer is a neuroscientist who has investigated conserved principles by which neurons and neural circuits control behaviour.

Therapies 98

Therapies Molecular Biology Laboratories Government 98

Fierce BioTech

JUNE 6, 2023

Harwell molecular biology spherical nucleic acid rare diseases Adaptive Biotechnologies Resource Type Whitepaper harwell logo.png Tue, 06/06/2023 - 09:31 Content Channel Devices Clinical Data Biotech Content Channel Fierce Biotech Homepage Landing Page Url More Info Byline Sponsored by: Harwell

Science 52

Science Molecular Biology Therapies Government 52

Drug Discovery World

JULY 8, 2022

The development is being overseen by real estate group Prologis, which has recently committed £1.65 million to support public arts and community activities at Cambridge Biomedical Campus. .

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Science Molecular Biology Laboratories Hospitals 130

DrugBank

MAY 15, 2024

But as molecular biology has advanced, so too has our approach to finding new drugs. Advancements in technology and a deeper understanding of molecular biology are beginning to turn the tide. Researchers would sift through natural extracts , hoping to stumble upon a compound that exhibited beneficial effects.

Small Molecule 83

Small Molecule Molecular Biology Drugs Disease 83

Drug Target Review

FEBRUARY 19, 2024

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. Can you tell us about your journey in the field of STEM and the challenges you encountered along the way?

Molecular Biology 110

Molecular Biology Science Protein Expression Production 110

FDA Law Blog: Drug Discovery

MAY 1, 2024

Sarah graduated with a cum laude degree in Cell and Molecular Biology from Towson University, a M.P.H. Sarah’s expertise will contribute to our mission of helping drug and biologic companies navigate the pathways from discovery to commercialization. from Johns Hopkins Bloomberg School of Public Health, and a J.D.

Drug Development 52

Drug Development Compliance Molecular Biology Clinical Trials 52

Codon

JULY 17, 2024

I want to see amateur biology thrive, and while a lot of regulations exist for a reason, I’m unconvinced that molecular biology requires all the crazy expensive equipment that has become associated with it. I mean, how did people do molecular biology fifty or one hundred years ago?

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Laboratories Engineering Molecular Biology Science 104