Science Daily: Pharmacology News
OCTOBER 17, 2024
A new study reveals how the duplication of the salivary amylase gene may not only have helped shape human adaptation to starchy foods, but may have occurred as far back as more than 800,000 years ago, long before the advent of farming.
Conversations in Drug Development Trends
OCTOBER 14, 2024
Autoimmune diseases and bone health conditions are not just medical challenges – they’re personal battles that millions of people fight every day. From the unpredictability of lupus flare-ups to the silent progression of osteoporosis, patients face daily struggles that can significantly impact their quality of life. Fortunately, advances in clinical research are providing hope for better treatments and outcomes.
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Perficient: Drug Development
OCTOBER 16, 2024
Addressing the Talent Shortage While fears of AI-driven job displacement dominate headlines, the real crisis looming is a $8.5 trillion talent shortage projected by 2030. Much like the famous ‘invisible gorilla’ experiment, where viewers focused on counting basketball passes miss a costumed figure walking through the scene, businesses risk overlooking a crucial element: the Employee Experience (EX).
FDA Law Blog: Biosimilars
OCTOBER 13, 2024
By Mark A. Tobolowsky — The Rare Pediatric Disease Priority Review Voucher program has had a bit of a tumultuous history in its 12 short years of existence. Designed to incentivize the development of drugs for pediatric rare diseases where such development may not otherwise have occurred, vouchers may be granted for drugs for serious or life-threatening rare diseases where the serious or life-threatening manifestations primarily affect individuals aged from birth to 18 years.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
BioPharma Drive: Drug Pricing
OCTOBER 16, 2024
The results provide the first clinical evidence of RNA editing, a burgeoning field that's drawn interest from biotechs and pharmaceutical companies alike.
Conversations in Drug Development Trends
OCTOBER 14, 2024
Autoimmune diseases and bone health conditions are not just medical challenges – they’re personal battles that millions of people fight every day. From the unpredictability of lupus flare-ups to the silent progression of osteoporosis, patients face daily struggles that can significantly impact their quality of life. Fortunately, advances in clinical research are providing hope for better treatments and outcomes.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
OCTOBER 17, 2024
THURSDAY, Oct. 17, 2024 -- A national recall of meat and poultry has been expanded to include close to 12 million pounds of products that may have been contaminated with listeria, U.S. health officials announced. In addition, the updated recall.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2024
Vyalev’s clearance is the second victory for AbbVie in Parkinson’s this year, following an April readout for a drug acquired through its Cerevel buyout.
Covalent Modifiers
OCTOBER 15, 2024
Xingyu Ma, Manyi Xu, Fengge Wang, Tingting Hu, Xinyuan Chena and Chong-Jing Zhang Chem. Commun. , 2024 DOI [link] Reversible covalent electrophiles with the advantages of both reversible and covalent interactions receive much attention in the fields of chemical biology and medicinal chemistry. Here, we report two electron-deficient olefins activated by amide and ester, amide-substituted acrylamide and methyl ester-substituted acrylamide, targeting thiols in a reversible covalent manner.
Science Daily: Pharmacology News
OCTOBER 16, 2024
According to new research, men and women rely on different biological systems for pain relief, which could help explain why our most powerful pain medications are often less effective in women.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
OCTOBER 17, 2024
THURSDAY, Oct. 17, 2024 -- Folks who want solid protection during the cold and flu season should get the influenza vaccine now, the U.S. Food and Drug Administration says. The ideal time to get the flu vaccine is by the end of October, the FDA said.
BioPharma Drive: Drug Pricing
OCTOBER 14, 2024
The deal would hand Lundbeck a treatment for a series of rare brain disorders that could, by the company's estimates, become a blockbuster product.
Covalent Modifiers
OCTOBER 12, 2024
Eric M. Merten and John D. Sears and Tina M. Leisner and P. Brian Hardy and Anirban Ghoshal and Mohammad Anwar Hossain and Kesatebrhan Haile Asressu and Peter J. Brown and Edwin G. Tse and Michael A. Stashko and Kelin Li and Jacqueline L. Norris-Drouin and Laura E. Herring and Angie L. Mordant and Thomas S. Webb and Christine A. Mills and Natalie K.
Science Daily: Pharmacology News
OCTOBER 16, 2024
Researchers have engineered bacteria as personalized cancer vaccines that activate the immune system to specifically seek out and destroy cancer cells.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
OCTOBER 16, 2024
WEDNESDAY, Oct. 16, 2024 -- The number of U.S. children who suffer seizures after swallowing prescription medications or illicit drugs has doubled in recent years, a new study finds. Drug poisonings among kids resulting in seizures increased from.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2024
The restructuring, which follows clinical setbacks in Alzheimer’s, Parkinson’s and tremor, will also involve the departure of five senior executives.
Collaborative Drug
OCTOBER 17, 2024
Nobel Prize in Chemistry, Lasker Award for Obesity Drugs, and Advances in Macrophage-Based Drug Delivery. and more.
Science Daily: Pharmacology News
OCTOBER 15, 2024
A recent study found that good physical fitness from childhood to adolescence is linked to better mental health in adolescence. These results are significant and timely, as mental health problems are currently a major societal challenge, affecting up to 25%--30% of young people. These findings suggest that improving physical fitness from childhood can help prevent mental health problems.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
OCTOBER 16, 2024
WEDNESDAY, Oct. 16, 2024 -- Most Americans 50 and older don’t place much trust in health advice generated by artificial intelligence, a new survey finds.About 74% of middle-aged and senior Americans would have very little to no trust in health info.
BioPharma Drive: Drug Pricing
OCTOBER 14, 2024
The agency agreed in court to allow compounding companies to continue producing copycat versions of Lilly’s fast-selling medicines while it reevaluates its recent decision to declare the drugs back in supply.
Covalent Modifiers
OCTOBER 15, 2024
Sang Joon Won, Yuxiang Zhang, Christopher J. Reinhardt,Lauren M. Hargis, Nicole S. MacRae,Kristen E. DeMeester,Evert Njomen,Jarrett R. Remsberg,Bruno Melillo, Benjamin F. Cravatt, Michael A. Erb Molecular Cell, 2024 [link] Pioneer transcription factors (TFs) bind to and open closed chromatin, facilitating engagement by other regulatory factors involved in gene activation or repression.
Science Daily: Pharmacology News
OCTOBER 17, 2024
A new vaccine provides hope for treating and even preventing the highly contagious and difficult-to-treat Clostridioides difficile infection, more commonly known as C. difficile or C. diff. In animal models, this first mRNA-LNP C. difficile vaccine was found to protect against C. difficile first-time infections and relapsing infections by inducing a robust immune response, promote clearance of existing C. diff bacteria from the gut, and even overcome deficits in host immunity to protect animals
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
OCTOBER 18, 2024
FRIDAY, Oct. 18, 2024 -- A global real-world study of the vaccine for respiratory syncytial virus (RSV) finds it offers folks aged 60 and over 80% protection against severe illness and/or hospitalization.With U.S. vaccination rates falling, "I.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2024
The French drugmaker will invest 300 million euros into a new entity that will develop lead isotope-based therapies for cancer under the Orano Med brand.
Covalent Modifiers
OCTOBER 15, 2024
Weizhi Weng, Ping Zhang, and Zhengying Pan Journal of the American Chemical Society 2024 DOI: 10.1021/jacs.4c06459 Naturally, kinases exert their activities in a highly regulated fashion. A number of ingenious approaches have been developed to artificially control kinase activity by external stimuli, such as the incorporation of unnatural amino acids or the fusion of additional protein domains; however, methods that directly modulate endogenous kinases in native cells are lacking.
Science Daily: Pharmacology News
OCTOBER 18, 2024
A species of tropical butterfly with unusually expanded brain structures display a fascinating mosaic pattern of neural expansion linked to a cognitive innovation.
Drugs.com
OCTOBER 17, 2024
THURSDAY, Oct. 17, 2024 -- An off-label clot-busting drug appears to work slightly better in treating stroke patients than an approved medication, a new review finds. The clot-buster tenecteplase is associated with a slightly higher likelihood of.
BioPharma Drive: Drug Pricing
OCTOBER 18, 2024
Detailed data from a Phase 2b/3 study of Merck’s treatment clesrovimab should support the company’s efforts to win approval by the 2025-2026 season.
Covalent Modifiers
OCTOBER 15, 2024
Weizhi Weng, Ping Zhang, and Zhengying Pan Journal of the American Chemical Society 2024 DOI: 10.1021/jacs.4c06459 Naturally, kinases exert their activities in a highly regulated fashion. A number of ingenious approaches have been developed to artificially control kinase activity by external stimuli, such as the incorporation of unnatural amino acids or the fusion of additional protein domains; however, methods that directly modulate endogenous kinases in native cells are lacking.
Science Daily: Pharmacology News
OCTOBER 17, 2024
The more men are concerned about appearing masculine, the less likely they will forgive a co-worker for a transgression such as missing an important meeting, a study has found. What's more, such men are also more likely seek revenge or avoid the transgressor, which contributes to an unhealthy and less effective work environment.
Drugs.com
OCTOBER 18, 2024
FRIDAY, Oct. 18, 2024 -- Intrauterine devices (IUDs) may raise the chances of a breast cancer diagnosis for women who use the hormonal birth control method, but that risk remains low, new research finds.In the study of 150,000 Danish women.
BioPharma Drive: Drug Pricing
OCTOBER 16, 2024
The pharma’s lawsuit focuses on scientific work that helped clear the path for creating mRNA vaccines to fight the COVID-19 pandemic.
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