2008 Cell Biology FDA Approval 
Drug Target Review
SEPTEMBER 19, 2023
In spite of current success and possibility to be a successful cell technology model, the integration of organ-on-chips into drug development process needs more optimisation to be validated for FDA approval. From 3D cell culture to organs-on-chips. Trends in Cell Biology. 2010;328(5986):1662-8. Ingber DE.
Drug Target Review
JANUARY 16, 2025
Macrocycles, by contrast, have a higher degree of cell permeability and are also capable of binding to protein surface sites due to their size and flexibility. 6 Among the well-known FDA-approved macrocyclic drugs are those that treat Hepatitis C, a disease with previously limited therapeutic options.
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