Remove Immune Response Remove Medical Chemistry Remove Pharmaceuticals
article thumbnail

How GPCR-targeting therapies are advancing the fight against inflammatory disease

Drug Target Review

Moreover, GPCRs have a complex pharmacology, with each acting as a kind of signalling hub for an array of downstream signals, in contrast to simpler receptors which are generally responsible for one signal. Stephan holds a PhD in medical chemistry from University of Strasbourg in France.

article thumbnail

Outsmarting immune suppression through GPCR innovation

Drug Target Review

These CCR8+ Tregs are known to suppress immune responses in the tumour microenvironment (TME), allowing cancers to grow unchecked. “DT-7012 Prior to joining Domain, Stephan established and led the Medicinal Chemistry Department at Faust Pharmaceuticals and was a senior scientist at Evotec.