Remove Immune Response Remove Medical Chemistry Remove Treatment
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How GPCR-targeting therapies are advancing the fight against inflammatory disease

Drug Target Review

Moreover, GPCRs have a complex pharmacology, with each acting as a kind of signalling hub for an array of downstream signals, in contrast to simpler receptors which are generally responsible for one signal. Stephan holds a PhD in medical chemistry from University of Strasbourg in France.

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Outsmarting immune suppression through GPCR innovation

Drug Target Review

Immuno-oncology has transformed cancer treatment, but for many patients, tumours remain resistant to even the most advanced immune checkpoint inhibitors. These CCR8+ Tregs are known to suppress immune responses in the tumour microenvironment (TME), allowing cancers to grow unchecked.