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Smaller Pharmacies, Bigger Impact: Inside Manufacturers’ Specialty Networks in 2025

Drug Channels

See The Top 15 Specialty Pharmacies of 2024: How PBMs, Health Systems, and Independents Are Shaping the Market. Today, we dive deeper. Drawing from DCIs new 2025 Economic Report on U.S.

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Beyond the Big Three PBMs: Examining a Potential Trend

Perficient: Drug Development

Among these, pharmacy benefit managers (PBMs) play a crucial role, handling reimbursements and negotiations with drug manufacturers and pharmacies. Three major PBM players – CVS Caremark, Express Scripts, and OptumRx – collectively command a significant 79% market share , orchestrating much of the industry’s dynamics.