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How GPCR-targeting therapies are advancing the fight against inflammatory disease

Drug Target Review

DT-9046 is an orally delivered small molecule that has reached pre-IND studies – making Domain the first company to successfully advance a small molecule candidate targeting PAR2. Stephan holds a PhD in medical chemistry from University of Strasbourg in France.

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Outsmarting immune suppression through GPCR innovation

Drug Target Review

Whether we are working with small molecules or larger biologics, our platform enables a precise design of innovative drug candidates with highly differentiated profiles.” Prior to joining Domain, Stephan established and led the Medicinal Chemistry Department at Faust Pharmaceuticals and was a senior scientist at Evotec.