Alta Sciences

DECEMBER 31, 2024

The issue also features a drug-drug interaction case study, in which the effects of two doses of a sponsors investigational product on the pharmacokinetics of multiple oral doses of clopidogrel, and a single dose of warfarin in healthy adult subjects were evaluated. The Altascientist, Issue 7, pg. The Altascientist, Issue 7, pg.

Therapies 52

Therapies Pharmacokinetics Pharmacogenetics Clinical Trials 52

DrugBank

JULY 14, 2025

Drug-drug interactions (DDI) are a significant concern in clinical trials, where the safe and effective administration of drugs to patients is crucial. The pharmacokinetic and pharmacodynamic properties of each drug and the patient’s individual variability contribute to the potential for interactions.

Clinical Development 52

Clinical Development Pharmacokinetics Drugs Clinical Trials 52

ASPET

APRIL 26, 2024

In this study, we investigated the systemic pharmacokinetics and subsequent CNS distribution of two potent HDACIs, vorinostat and quisinostat, in the murine model. A knowledge of CNS exposure (K p,uu ), time to peak, and duration can inform dosing strategies in preclinical and clinical trials in selected CNS tumors.

Pharmacogenetics 100

Pharmacogenetics Pharmacokinetics Clinical Trials Trials 100