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Involved in various physiological processes, such as vision, taste, smell, immuneresponse and neurotransmission, GPCRs are activated by various molecules including hormones, neurotransmitters and environmental stimuli, which trigger a cascade of cellular events that help regulate bodily functions.
What are the risks of over-reliance on healthy donor material in early-stage research, and how can decision-makers ensure a balanced integration of diseased material to avoid potential gaps when transitioning to clinicaltrials? Healthy cells may also serve as a valuable control in experiments.
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