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G protein-coupled receptors (GPCRs) are a highly validated drug target family – accounting for 30-35 percent of all approved drugs. Despite this, the therapeutic potential of targeting most GPCRs remains untapped, as only 10 percent of GPCRs have been drugged.
There have been several studies that have reported the ability of infectious disease agents to be drug resistant. Studies have shown that targeting some expression gene sites could lead to the production of new drugs as indicated. 7,13 The use of Plants extract is important in drug discovery.
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