Remove Drugs Remove Medical Chemistry Remove Research
article thumbnail

How GPCR-targeting therapies are advancing the fight against inflammatory disease

Drug Target Review

G protein-coupled receptors (GPCRs) are a highly validated drug target family – accounting for 30-35 percent of all approved drugs. Despite this, the therapeutic potential of targeting most GPCRs remains untapped, as only 10 percent of GPCRs have been drugged.

Disease 59
article thumbnail

Addressing increasingly resistant drugs by infectious agents

Drug Target Review

There have been several studies that have reported the ability of infectious disease agents to be drug resistant. 1 Research questions: How are infectious agents able to survive in the vector but infect their host? Studies have shown that targeting some expression gene sites could lead to the production of new drugs as indicated.

Drugs 111