New Drug Approvals

JULY 25, 2025

16] Population pharmacokinetics (PK) of vamorolone was shown to fit to a 1-compartment model with zero-order absorption, with both adult men and young boys showing dose-linearity of PK parameters for the doses examined, and no accumulation of the drug during daily dosing. . September 2016). mg/kg/day suggesting benefit. [15]

FDA 62

FDA FDA Approval Treatment Clinical Trials 62

Drug Target Review

NOVEMBER 1, 2023

2,8-10 However, the number of compounds with satisfying pharmacokinetic parameters (PKD) are limited, with most unable to cross the blood-brain barrier or go sufficiently deep into a malignant tumour. 2016 Jun 23;59(12):5604–21. The Journal of Cell Biology. 2016 Sep;7(1):11248. Frontiers in Medicine. 2018 Jun 13;5.

Clinical Trials 134

Clinical Trials Trials Small Molecule Disease 134

New Drug Approvals

JANUARY 9, 2024

As such, it has been proposed that inhibiting CDK7 would provide a potent means of inhibiting cell cycle progression, which may be especially relevant given that there is compelling evidence from gene knockout studies in mice for lack of an absolute requirement for CDK2, CDK4 and CDK6 for the cell cycle at least in most cell types (M alumbres et al.,

Production 62

Production DNA RNA Regulations 62