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High Throughput Screening (HTS)

Sygnature Discovery

Collaboration with customers and Sygnatures computational chemists ensures quality hit identification using computational chemistry triage, counter screens, and orthogonal assays. Central to our automation is the Echo acoustic dispensing technology, ensuring highly accurate compound delivery.

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Target-directed cancer: protein-ligand interactions  

Drug Target Review

For example, in the screening stage of a project we are trying to find initial starting points for optimisation by our medicinal and computational chemistry colleagues. We often screen using a biochemical assay, but we can conduct cell-based screening as well. We can screen with many different formats and modalities.