Drug Discovery World

SEPTEMBER 2, 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With the launch of an international clinical trial investigating BioNTech’s mRNA lung cancer vaccine announced this week, our news highlights focus on clinical trials, including studies of a monoclonal antibody and small molecule GLP-1 agonist for obesity, and a muscarinic M4 selective ag

Small Molecule 147

Small Molecule Clinical Trials Vaccine Trials 147

Science Daily: Pharmacology News

SEPTEMBER 2, 2024

Securing the world's water supply is one of the greatest challenges of our time. Researchers are now presenting an alternative method for quantifying the global risk of water scarcity. Results indicate higher risks to water supply than previously expected if accounting for the environmental conditions and governability where rain is produced.

Government 130

Government Research 130

Drug Discovery World

SEPTEMBER 2, 2024

NuCana has revealed that the NuTide:323 colorectal cancer study is being discontinued following a pre-planned initial analysis and recommendation from the NuTide:323 Study Steering Committee. The Steering Committee believed that the combination of NUC-3373 with leucovorin, irinotecan and bevacizumab (NUFIRI+bev) was unlikely to achieve the study’s primary objective of superior progression free survival (PFS) compared to the control arm of 5-FU, leucovorin, irinotecan and bevacizumab (FOLFIRI+bev

Trials 147

Trials Treatment Clinical Trials Drugs 147

Science Daily: Pharmacology News

SEPTEMBER 2, 2024

New research has uncovered an extraordinary mechanism of cell division in Corynebacterium matruchotii, one of the most common bacteria living in dental plaque. The filamentous bacterium doesn't just divide, it splits into multiple cells at once, a rare process called multiple fission.

Research 121

Research 121

Advertisement

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

SEPTEMBER 2, 2024

Biopharma ranks amongst the highest scoring sectors for employee wellbeing and comes top for work-life balance and self-care, according to a survey conducted by Great Place To Work. Leveraging their research-based Trust Index Survey, Great Place To Work conducted a UK population study, surveying 2,200 employees across 11 sectors to create The State of Employee Wellbeing in the Workplace Report 2024.

Packaging 147

Packaging Production Research Drugs 147

Drugs.com

SEPTEMBER 2, 2024

MONDAY, Sept. 2, 2024 -- Could a simple blood test help predict a woman’s three-decade risk of heart disease?Yes, claims new research that found women with high levels of three specific blood markers had a greater than threefold increased risk for h.

Disease 111

Disease Research 111

Science Daily: Pharmacology News

SEPTEMBER 2, 2024

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial.

Clinical Trials 110

Clinical Trials Trials Hospitals International 110

Drug Discovery World

SEPTEMBER 2, 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With the launch of an international clinical trial investigating BioNTech’s mRNA lung cancer vaccine announced this week, our news highlights focus on clinical trials, including studies of a monoclonal antibody and small molecule GLP-1 agonist for obesity, and a muscarinic M4 selective ag

Small Molecule 130

Small Molecule Clinical Trials Vaccine International 130

Drugs.com

SEPTEMBER 2, 2024

MONDAY, Sept 2, 2024 -- Endometriosis can be a painful, debilitating condition for many women, but new research suggests even more serious consequences: higher odds for heart attacks or strokes.Endometriosis occurs when uterine tissue that normally.

Research 97

Research 97

Drug Discovery World

SEPTEMBER 2, 2024

The European Commission (EC) has approved Braftovi (encorafenib) in combination with Mektovi (binimetinib) for the treatment of adult patients with advanced non-small cell lung cancer (NSCLC) with a BRAFV600E mutation. The EC decision followw a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) issued on 25 July. The US Food and Drug Administration (FDA) approved the combination treatment for adults with BRAFV600E mutant metastatic NSCLC in October 2023.

Treatment 130

Treatment FDA Approval Laboratories Trials 130

Advertisement

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

SEPTEMBER 2, 2024

MONDAY, Sept. 2, 2024 -- Hospitals see more admissions for heart attacks in the days after cold weather sets in, new research shows."Individuals may be particularly vulnerable to acute cardiac events during periods of cold stress," said study lead.

Hospitals 80

Hospitals Research 80

Science Daily: Pharmacology News

SEPTEMBER 2, 2024

New research suggests that alternative splicing may have an even greater influence on biology than just by creating new protein isoforms. The study shows that the biggest impact of alternative splicing may come via its role in regulating gene expression levels.

Regulations 76

Regulations Research 76

Drugs.com

SEPTEMBER 2, 2024

MONDAY, Sept. 2, 2024 -- If you're lucky enough to survive a battle with the bloodstream infection sepsis, risks of a recurrence that sends you back to hospital within a month remain high, new data shows.In a study involving over 7,100 patients.

Hospitals 79

Hospitals 79

On Medicine

SEPTEMBER 2, 2024

As of 1st of September 2024, the BMC Blog Network is closed for new contributions. If you would like to write a blog about your research, please visit the Research Communities or get in touch with the team. The Springer Nature Research Communities are a digital community and blog platform that connects the global research community and wider audiences with each other and provides opportunities to discover and explore the latest research.

Research 57

Research 57

Advertisement

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Perficient: Drug Development

SEPTEMBER 2, 2024

Excited to announce the launch of our new blog series: UX in Universal Design: Physical Disabilities in Health Systems. This series will dive deep into the critical role that usability and user experience (UX) play in creating healthcare environments that are not just accessible, but truly inclusive for individuals with physical disabilities. Why This Series Matters Healthcare is a fundamental right, yet many individuals with physical disabilities encounter barriers that prevent them from access

Compliance 52

Compliance Hospitals Production 52

Quanticate

SEPTEMBER 2, 2024

Clinical research serves as the foundation for advancing medical knowledge, improving patient care, and ensuring the safety and efficacy of new investigational products. As a result, clinical trials must be performed to the highest degree of scientific and ethical standards, for results to be recognised as credible and the trial deemed as successful.

Clinical Trials 52

Clinical Trials Clinical Research Trials Production 52

Perficient: Drug Development

SEPTEMBER 2, 2024

UX in Universal Design , where we focus on the importance of designing health systems that cater to individuals with physical disabilities. In this installment, we explore why addressing the needs of people with physical disabilities is crucial in healthcare environments, and how Universal Design principles can lead to more inclusive, accessible, and effective health systems.

Compliance 52

Compliance Treatment Hospitals 52

Zobio

SEPTEMBER 2, 2024

In person From September 9 to 12, Welmoet de Winter, one of our scientists, will be attending the DiPIA conference in Uppsala, Sweden. DiPIA, or Developments in Protein Interaction Analysis, is a global scientific conference hosted by Cytiva. This event brings together industry peers to share best practices, research, and new applications in the field.

Research 40

Research Drugs 40

thought leadership

SEPTEMBER 2, 2024

Navigate the complexities of EU GMP compliance with ProPharma’s expert guidance. Learn essential strategies for ensuring quality and safety in pharmaceutical manufacturing.

Compliance 40

Compliance Pharmaceuticals 40

FDA Law Blog: Biosimilars

SEPTEMBER 2, 2024

FDA 64

FDA 64

Drug Discovery World

SEPTEMBER 2, 2024

In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In recent years, adeno-associated virus (AAV) vectors have been launched and are considered one of the main platforms for gene therapy.

Virus 130

Virus DNA Clinical Trials Engineering 130

Drug Discovery World

SEPTEMBER 2, 2024

Traditional hybridoma technology has long struggled with inefficiencies, especially in producing rabbit monoclonal antibodies. Join DDW on 9 September 3PM BST to find out how Fujifilm Wako has surmounted these challenges by integrating DNA immunisation with their proprietary single B-cell cloning technique, paving the way for next-generation antibody production.

Production 147

Production DNA Immune Response Pharmaceuticals 147