New Drug Approvals

JUNE 5, 2025

nM) and cell based assays ( EC 50 =89 nM). nM) and cell based assays ( EC 50 =89 nM). Gamcemetinib CAS 1887069-10-4 CC-99677 , OS2IR8TV1O Molecular Weight 469.94 Gamcemetinib CAS 1887069-10-4 CC-99677 , OS2IR8TV1O Molecular Weight 469.94 Gamcemetinib is extracted from patent WO2020236636, compound 1.

Cell Based Assays 52

Cell Based Assays Clinical Pharmacology Pharmacokinetics Trials 52

BMG Labtech

JULY 2, 2025

In measuring cell viability, membrane integrity is a key indicator, as only viable cells with intact membranes are counted as living. Next to cell viability assays, cell-based assays can also be employed to analyse other cellular events like cytotoxicity, reactive oxygen species (ROS) production or cell metabolism.

Cell Based Assays 52

Cell Based Assays Production Cell Biology 52

DrugBank

FEBRUARY 12, 2025

Key techniques include high-throughput screening (HTS), cell-based assays, and animal models. Cell-Based Assays In vitro, drug efficacy, and toxicity testing in cell cultures provide valuable preclinical data.

Cell Based Assays 52

Cell Based Assays Drugs Pharmacokinetics Disease 52

Molecular Design

JUNE 8, 2023

I would argue that the L2021 study has absolutely no relevance whatsoever to the selection of compounds for development since the team will have data available that enables them to rule out the vast majority of the project compounds for nomination.

Cell Based Assays 62

Cell Based Assays Small Molecule Drugs Marketing 62

The Pharma Data

OCTOBER 15, 2020

ASLAN003 is a highly selective and potent inhibitor of human DHODH (IC 50 = 35 nM) and has been shown to be more than 30 times more potent at inhibiting the DHODH enzyme in cell free and cell-based assays than the first generation inhibitor teriflunomide.

Pharmaceuticals 40

Pharmaceuticals Cell Based Assays Clinical Development Treatment 40

Elrig

APRIL 29, 2024

Janne’s passion for the topic of ethics and the future of AI has led her to attend conferences and events to build her knowledge as an attendee and be invited to panels and fireside chats to discuss. From small start-ups through to big pharma, Janne’s experience covers it all.

Bioinformatics 59

Bioinformatics Drugs Molecular Biology Cell Based Assays 59

BMG Labtech

OCTOBER 30, 2023

In this blog, we highlight some of the solutions available for researchers to tackle atherosclerotic vascular disease: from fundamental research rooted in ischemia-reperfusion studies and cell-based assays to drug discovery efforts and the early detection of drug-related side effects. What is atherosclerotic vascular disease?

Disease 52

Disease Cell Based Assays Research Drugs 52